KEGG   PATHWAY: ahf00053
Entry
ahf00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Arachis hypogaea (peanut)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ahf00053  Ascorbate and aldarate metabolism
ahf00053

Module
ahf_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:ahf00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Arachis hypogaea (peanut) [GN:ahf]
Gene
112709782  UDP-glucose 6-dehydrogenase 3 [KO:K00012] [EC:1.1.1.22]
112734145  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
112750255  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
112791983  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
112716472  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
112797843  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
112722570  UDP-glucose 6-dehydrogenase 3 [KO:K00012] [EC:1.1.1.22]
112782724  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
112801640  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
112744548  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
114927234  UDP-sugar pyrophosphorylase 1 [KO:K12447] [EC:2.7.7.64]
112706017  UDP-sugar pyrophosphorylase 1 [KO:K12447] [EC:2.7.7.64]
112764737  UDP-sugar pyrophosphorylase 1 [KO:K12447] [EC:2.7.7.64]
112751435  glucuronokinase 1 [KO:K16190] [EC:2.7.1.43]
112723889  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
112801916  glucuronokinase 1 [KO:K16190] [EC:2.7.1.43]
112709988  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
112732338  inositol oxygenase 2 [KO:K00469] [EC:1.13.99.1]
112732601  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
112711190  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
112711194  inositol oxygenase 5-like [KO:K00469] [EC:1.13.99.1]
112790684  inositol oxygenase 2 [KO:K00469] [EC:1.13.99.1]
112751307  inositol oxygenase 2 [KO:K00469] [EC:1.13.99.1]
112751309  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
112701562  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
112776910  inositol oxygenase 5-like [KO:K00469] [EC:1.13.99.1]
112778657  inositol oxygenase 5-like [KO:K00469] [EC:1.13.99.1]
112778658  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
112778660  inositol oxygenase 5-like [KO:K00469] [EC:1.13.99.1]
112738032  inositol oxygenase 2 isoform X1 [KO:K00469] [EC:1.13.99.1]
112779482  inositol oxygenase 1 isoform X1 [KO:K00469] [EC:1.13.99.1]
112704118  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
112763142  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
112802046  inositol oxygenase 4 [KO:K00469] [EC:1.13.99.1]
112802047  inositol oxygenase 2 [KO:K00469] [EC:1.13.99.1]
112765725  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
112748273  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112748305  aldo-keto reductase family 4 member C10 [KO:K00002] [EC:1.1.1.2]
112748321  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112748327  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112748336  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112697292  aldose reductase [KO:K00002] [EC:1.1.1.2]
112755192  aldose reductase [KO:K00002] [EC:1.1.1.2]
112796908  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112796910  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112743521  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
112743522  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
112743524  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112727795  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112727799  NADPH-dependent aldo-keto reductase, chloroplastic isoform X1 [KO:K00002] [EC:1.1.1.2]
112727801  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112727802  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
112695261  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
112734285  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
112754172  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
112755425  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
112755430  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
112755578  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
112755579  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
112726583  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
112695425  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
112758272  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
112790099  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
112733694  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
112791627  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
112701936  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
112720253  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
112766070  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
112796012  inositol-phosphate phosphatase [KO:K10047] [EC:3.1.3.25 3.1.3.93]
112722831  inositol-phosphate phosphatase isoform X1 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
112741308  inositol-phosphate phosphatase [KO:K10047] [EC:3.1.3.25 3.1.3.93]
112706277  inositol-phosphate phosphatase isoform X1 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
112771437  bifunctional phosphatase IMPL2, chloroplastic isoform X1 [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
112703118  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
112703639  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
112765607  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
112728671  L-galactose dehydrogenase isoform X1 [KO:K17744] [EC:1.1.1.316]
112791338  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
112745243  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
112727599  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
112789476  UDP-glucuronate 4-epimerase 2 [KO:K08679] [EC:5.1.3.6]
112803764  UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
112805869  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
112749593  UDP-glucuronate 4-epimerase 5 [KO:K08679] [EC:5.1.3.6]
112792646  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
112752793  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
112699270  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
112795687  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
112736244  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
112755260  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
112737402  UDP-glucuronate 4-epimerase 2 [KO:K08679] [EC:5.1.3.6]
112721876  UDP-glucuronate 4-epimerase 5 [KO:K08679] [EC:5.1.3.6]
112723482  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
112740990  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
112800884  UDP-glucuronate 4-epimerase 5 [KO:K08679] [EC:5.1.3.6]
112728252  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
112728860  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
112732608  monodehydroascorbate reductase, chloroplastic/mitochondrial isoform X1 [KO:K08232] [EC:1.6.5.4]
112790853  monodehydroascorbate reductase, chloroplastic/mitochondrial isoform X1 [KO:K08232] [EC:1.6.5.4]
112696669  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
112697310  monodehydroascorbate reductase 4, peroxisomal [KO:K08232] [EC:1.6.5.4]
112754484  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
112755216  monodehydroascorbate reductase 4, peroxisomal isoform X1 [KO:K08232] [EC:1.6.5.4]
112797562  monodehydroascorbate reductase, seedling isozyme [KO:K08232] [EC:1.6.5.4]
112758770  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
112744255  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
112786625  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
112708373  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
112789081  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
112747725  L-ascorbate peroxidase 3-like isoform X1 [KO:K00434] [EC:1.11.1.11]
112771587  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
112772858  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
112736565  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
112737011  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
112706052  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
112800332  L-ascorbate peroxidase 3-like isoform X1 [KO:K00434] [EC:1.11.1.11]
112764605  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
112707898  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
112770022  probable glutathione S-transferase DHAR2, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
112733706  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
112712312  glutathione S-transferase DHAR2 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
112791636  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
112795103  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
112776849  glutathione S-transferase DHAR2 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
112789707  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112734156  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112734158  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112734159  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112791994  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112791995  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112791996  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112795565  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
112796630  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112796633  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112796634  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112702168  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
112720309  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112740846  LOW QUALITY PROTEIN: L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
112741915  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112741916  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112741917  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
112764247  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
112788835  aldehyde dehydrogenase family 3 member F1 isoform X2 [KO:K00128] [EC:1.2.1.3]
112802492  aldehyde dehydrogenase family 2 member B7, mitochondrial isoform X1 [KO:K00128] [EC:1.2.1.3]
112770600  aldehyde dehydrogenase family 3 member F1 isoform X1 [KO:K00128] [EC:1.2.1.3]
112789616  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
112733037  aldehyde dehydrogenase family 3 member H1 isoform X1 [KO:K00128] [EC:1.2.1.3]
112748899  uncharacterized protein LOC112748899 isoform X1 [KO:K00128] [EC:1.2.1.3]
112695582  aldehyde dehydrogenase family 2 member B4, mitochondrial [KO:K00128] [EC:1.2.1.3]
112733931  aldehyde dehydrogenase family 2 member B7, mitochondrial [KO:K00128] [EC:1.2.1.3]
112791071  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
112750770  aldehyde dehydrogenase family 2 member B7, mitochondrial isoform X1 [KO:K00128] [EC:1.2.1.3]
112791810  aldehyde dehydrogenase family 2 member B7, mitochondrial [KO:K00128] [EC:1.2.1.3]
112773076  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
112773183  aldehyde dehydrogenase family 3 member I1, chloroplastic [KO:K00128] [EC:1.2.1.3]
112717712  aldehyde dehydrogenase family 2 member C4-like [KO:K00128] [EC:1.2.1.3]
112736727  aldehyde dehydrogenase family 3 member F1 isoform X1 [KO:K00128] [EC:1.2.1.3]
112720319  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
112722365  aldehyde dehydrogenase family 2 member B4, mitochondrial [KO:K00128] [EC:1.2.1.3]
112705758  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
112706053  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
112706654  aldehyde dehydrogenase family 3 member F1 isoform X1 [KO:K00128] [EC:1.2.1.3]
112764215  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
112765057  aldehyde dehydrogenase family 3 member H1 isoform X1 [KO:K00128] [EC:1.2.1.3]
112707970  aldehyde dehydrogenase family 3 member I1, chloroplastic-like [KO:K00128] [EC:1.2.1.3]
112790524  aldehyde dehydrogenase family 7 member A1 isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
112738351  aldehyde dehydrogenase family 7 member A1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
ahf00020  Citrate cycle (TCA cycle)
ahf00040  Pentose and glucuronate interconversions
ahf00051  Fructose and mannose metabolism
ahf00520  Amino sugar and nucleotide sugar metabolism
ahf00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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