KEGG   PATHWAY: aip00053
Entry
aip00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Arachis ipaensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
aip00053  Ascorbate and aldarate metabolism
aip00053

Module
aip_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:aip00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Arachis ipaensis [GN:aip]
Gene
107643688  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
107635385  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
107623187  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
107634299  UDP-glucose 6-dehydrogenase 3 [KO:K00012] [EC:1.1.1.22]
107631835  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
107606001  UDP-sugar pyrophosphorylase 1 [KO:K12447] [EC:2.7.7.64]
107644551  glucuronokinase 1 [KO:K16190] [EC:2.7.1.43]
107628483  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
107615784  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
107630625  inositol oxygenase 2 [KO:K00469] [EC:1.13.99.1]
107634346  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
107644461  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
107644462  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
107632508  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
107607125  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
107616834  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
107607828  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
107619399  inositol oxygenase 1 [KO:K00469] [EC:1.13.99.1]
110266908  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
107625601  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
107639405  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
107625599  NADPH-dependent aldo-keto reductase, chloroplastic isoform X1 [KO:K00002] [EC:1.1.1.2]
107625598  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
107639407  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
107605189  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
107648068  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
107624247  probable L-gulonolactone oxidase 6 isoform X2 [KO:K00103] [EC:1.1.3.8]
107605190  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
107645815  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
107633751  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
107608900  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
107624932  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
107638701  inositol-phosphate phosphatase [KO:K10047] [EC:3.1.3.25 3.1.3.93]
107636682  inositol-phosphate phosphatase isoform X1 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
107609158  bifunctional phosphatase IMPL2, chloroplastic isoform X1 [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
107613726  bifunctional phosphatase IMPL2, chloroplastic isoform X1 [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
107626271  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
107625443  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
107638438  UDP-glucuronate 4-epimerase 6 isoform X1 [KO:K08679] [EC:5.1.3.6]
107629431  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
107627806  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
107647605  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
107629739  UDP-glucuronate 4-epimerase 2 [KO:K08679] [EC:5.1.3.6]
107641640  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
107630630  UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
107643020  LOW QUALITY PROTEIN: UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
107626404  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
107635140  monodehydroascorbate reductase-like [KO:K08232] [EC:1.6.5.4]
107648266  monodehydroascorbate reductase-like [KO:K08232] [EC:1.6.5.4]
107633439  LOW QUALITY PROTEIN: monodehydroascorbate reductase 5, mitochondrial [KO:K08232] [EC:1.6.5.4]
107605336  monodehydroascorbate reductase 4, peroxisomal isoform X1 [KO:K08232] [EC:1.6.5.4]
107641638  L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
107611695  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
107629166  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
107628775  L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
107612004  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
107606045  probable L-ascorbate peroxidase 6, chloroplastic [KO:K00434] [EC:1.11.1.11]
107611072  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
107618632  glutathione S-transferase DHAR2 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
107627590  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107634769  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107636273  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107609914  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
107633938  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107637689  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107616629  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107634770  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107638335  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
110271475  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
107625292  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
107629027  aldehyde dehydrogenase family 3 member F1 isoform X3 [KO:K00128] [EC:1.2.1.3]
107642833  methylmalonate semialdehyde dehydrogenase [acylating] isoform X1 [KO:K00128] [EC:1.2.1.3]
107644014  aldehyde dehydrogenase family 2 member B7, mitochondrial isoform X2 [KO:K00128] [EC:1.2.1.3]
107609401  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
107630921  aldehyde dehydrogenase family 3 member H1 isoform X2 [KO:K00128] [EC:1.2.1.3]
107611917  aldehyde dehydrogenase family 3 member I1, chloroplastic-like [KO:K00128] [EC:1.2.1.3]
107631463  aldehyde dehydrogenase family 2 member B7, mitochondrial isoform X1 [KO:K00128] [EC:1.2.1.3]
107606046  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
107632337  aldehyde dehydrogenase family 2 member B4, mitochondrial [KO:K00128] [EC:1.2.1.3]
107630450  aldehyde dehydrogenase family 7 member A1 isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
aip00020  Citrate cycle (TCA cycle)
aip00040  Pentose and glucuronate interconversions
aip00051  Fructose and mannose metabolism
aip00520  Amino sugar and nucleotide sugar metabolism
aip00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

DBGET integrated database retrieval system