KEGG   PATHWAY: amm00230
Entry
amm00230                    Pathway                                
Name
Purine metabolism - Amycolatopsis mediterranei S699
Class
Metabolism; Nucleotide metabolism
Pathway map
amm00230  Purine metabolism
amm00230

Module
amm_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:amm00230]
amm_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:amm00230]
amm_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:amm00230]
amm_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:amm00230]
amm_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:amm00230]
amm_M00546  Purine degradation, xanthine => urea [PATH:amm00230]
amm_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:amm00230]
amm_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:amm00230]
Other DBs
GO: 0006163 0042278
Organism
Amycolatopsis mediterranei S699 [GN:amm]
Gene
AMES_0080  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
AMES_8108  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
AMES_4689  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
AMES_8898  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
AMES_8949  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
AMES_0804  purN; phosphoribosylglycinamide formyltransferase 1 [KO:K11175] [EC:2.1.2.2]
AMES_8910  purL; phosphoribosylformylglycinamidine synthase [KO:K23269] [EC:6.3.5.3]
AMES_8914  purL; phosphoribosylformylglycinamidine synthase [KO:K23264] [EC:6.3.5.3]
AMES_8913  purL; phosphoribosylformylglycinamidine synthase [KO:K23265] [EC:6.3.5.3 3.5.1.2]
AMES_8897  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
AMES_0988  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
AMES_0989  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
AMES_2164  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
AMES_8923  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
AMES_8930  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
AMES_0805  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
AMES_5232  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
AMES_7245  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
AMES_9053  nucleotidase [KO:K01081] [EC:3.1.3.5]
AMES_7700  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AMES_3407  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AMES_8380  nagD; NagD protein [KO:K02566] [EC:3.1.3.5]
AMES_0905  punA; purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
AMES_2924  yfiH; multi-copper oxidoreductase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
AMES_8620  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
AMES_0769  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
AMES_0772  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
AMES_6615  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
AMES_7585  nucleoside triphosphatase [KO:K01519] [EC:3.6.1.66]
AMES_3676  carbon-monoxide dehydrogenase large subunit [KO:K11177] [EC:1.17.1.4]
AMES_3007  carbon-monoxide dehydrogenase large subunit [KO:K11177] [EC:1.17.1.4]
AMES_3600  carbon-monoxide dehydrogenase large subunit [KO:K11177] [EC:1.17.1.4]
AMES_5681  carbon-monoxide dehydrogenase medium subunit [KO:K11178] [EC:1.17.1.4]
AMES_3678  carbon-monoxide dehydrogenase medium subunit [KO:K11178] [EC:1.17.1.4]
AMES_3008  carbon-monoxide dehydrogenase medium subunit [KO:K11178] [EC:1.17.1.4]
AMES_3601  carbon-monoxide dehydrogenase medium subunit [KO:K11178] [EC:1.17.1.4]
AMES_5682  carbon-monoxide dehydrogenase small subunit [KO:K13483]
AMES_3679  carbon-monoxide dehydrogenase small subunit [KO:K13483]
AMES_3602  carbon-monoxide dehydrogenase small subunit [KO:K13483]
AMES_0780  guaA; GMP synthase (glutamine-hydrolysing) [KO:K01951] [EC:6.3.5.2]
AMES_7950  guaB; IMP dehydrogenase [KO:K26110] [EC:1.7.1.7]
AMES_4531  guaD; deaminase [KO:K01487] [EC:3.5.4.3]
AMES_2727  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
AMES_2367  nrdA; ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
AMES_2850  nrdA; ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
AMES_8364  nrdB; ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
AMES_2849  nrdB; ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
AMES_6499  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
AMES_2829  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
AMES_5230  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
AMES_0461  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
AMES_2945  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
AMES_8069  ppx; Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
AMES_3315  RelA/SpoT domain-containing protein [KO:K07816] [EC:2.7.6.5]
AMES_0261  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
AMES_1561  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
AMES_8961  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
AMES_2169  adenosine kinase [KO:K00856] [EC:2.7.1.20]
AMES_4614  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
AMES_2969  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
AMES_0860  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
AMES_0698  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
AMES_2129  phosphohydrolase [KO:K03651] [EC:3.1.4.53]
AMES_5263  HIT family hydrolase [KO:K19710] [EC:2.7.7.53]
AMES_2816  cysC; adenylylsulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
AMES_6561  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
AMES_6560  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
AMES_2817  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
AMES_1910  urate oxidase [KO:K00365] [EC:1.7.3.3]
AMES_1912  transthyretin [KO:K07127] [EC:3.5.2.17]
AMES_1913  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
AMES_5934  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
AMES_1915  allB; L-hydantoinase/allantoinase [KO:K01466] [EC:3.5.2.5]
AMES_1916  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
AMES_8319  ureC; urease alpha subunit [KO:K01428] [EC:3.5.1.5]
AMES_8320  ureB; urease beta subunit [KO:K01429] [EC:3.5.1.5]
AMES_8321  ureA; urease gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
amm00030  Pentose phosphate pathway
amm00220  Arginine biosynthesis
amm00250  Alanine, aspartate and glutamate metabolism
amm00260  Glycine, serine and threonine metabolism
amm00340  Histidine metabolism
amm00630  Glyoxylate and dicarboxylate metabolism
amm00730  Thiamine metabolism
amm00740  Riboflavin metabolism
amm00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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