KEGG   PATHWAY: amou00564
Entry
amou00564                   Pathway                                
Name
Glycerophospholipid metabolism - Anopheles moucheti
Class
Metabolism; Lipid metabolism
Pathway map
amou00564  Glycerophospholipid metabolism
amou00564

Module
amou_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:amou00564]
amou_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:amou00564]
Other DBs
GO: 0006650
Organism
Anopheles moucheti [GN:amou]
Gene
128305759  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic isoform X1 [KO:K00006] [EC:1.1.1.8]
128310087  glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
128299815  glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
128299290  glycerol-3-phosphate acyltransferase 3 isoform X1 [KO:K13506] [EC:2.3.1.15]
128298470  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [KO:K13509] [EC:2.3.1.51]
128304700  1-acyl-sn-glycerol-3-phosphate acyltransferase beta-like [KO:K13509] [EC:2.3.1.51]
128300200  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
128305956  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
128305532  putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]
128305713  phospholipid phosphatase 1-like [KO:K01080] [EC:3.1.3.4]
128300203  phosphatidate phosphatase LPIN3 [KO:K15728] [EC:3.1.3.4]
128301837  phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
128298451  diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
128299661  diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
128303642  diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
128305845  diacylglycerol kinase 1 [KO:K00901] [EC:2.7.1.107]
128306417  eye-specific diacylglycerol kinase [KO:K00901] [EC:2.7.1.107]
128309448  cholinephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
128301038  phospholipase D2 [KO:K01115] [EC:3.1.4.4]
128306954  5'-3' exonuclease PLD3-like [KO:K16860] [EC:3.1.4.4]
128298392  uncharacterized protein LOC128298392 [KO:K01047] [EC:3.1.1.4]
128299793  group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
128309400  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
128301440  group 3 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
128301885  85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
128306931  lysophosphatidylcholine acyltransferase-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
128306990  lysophosphatidylcholine acyltransferase-like isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
128301605  lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
128301873  phospholipase A2 group XV-like [KO:K06129] [EC:3.1.1.5]
128303528  acyl-protein thioesterase 1 [KO:K06130] [EC:3.1.1.5]
128306924  neuropathy target esterase sws isoform X1 [KO:K14676] [EC:3.1.1.5]
128305040  glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
128299530  choline O-acetyltransferase isoform X1 [KO:K00623] [EC:2.3.1.6]
128299460  acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
128306505  LOW QUALITY PROTEIN: acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
128300265  choline/ethanolamine kinase isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
128309881  choline-phosphate cytidylyltransferase B-like [KO:K00968] [EC:2.7.7.15]
128301109  ethanolaminephosphotransferase 1 isoform X1 [KO:K00993] [EC:2.7.8.1]
128302180  ethanolaminephosphotransferase 1 isoform X1 [KO:K00993] [EC:2.7.8.1]
128306791  ethanolamine kinase [KO:K00894] [EC:2.7.1.82]
128300651  ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
128307074  alanine--glyoxylate aminotransferase 2-like [KO:K14286] [EC:4.2.3.2]
128305530  phosphatidate cytidylyltransferase, photoreceptor-specific [KO:K00981] [EC:2.7.7.41]
128308144  phosphatidylserine synthase [KO:K08729] [EC:2.7.8.-]
128309550  phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
128305516  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
128306907  probable cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
128302251  tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
128304304  acyl-CoA:lysophosphatidylglycerol acyltransferase 1-like [KO:K13514] [EC:2.3.1.-]
128296685  CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
128303279  lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
amou00010  Glycolysis / Gluconeogenesis
amou00260  Glycine, serine and threonine metabolism
amou00561  Glycerolipid metabolism
amou00562  Inositol phosphate metabolism
amou00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
amou00565  Ether lipid metabolism
amou00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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