KEGG   PATHWAY: atri04626
Entry
atri04626                   Pathway                                
Name
Plant-pathogen interaction - Amaranthus tricolor (tampala)
Description
Plants lack animal-like adaptive immunity mechanisms, and therefore have evolved a specific system with multiple layers against invading pathogens. The primary response includes the perception of pathogens by cell-surface pattern-recognition receptors (PRRs) and is referred to as PAMP-triggered immunity (PTI). Activation of FLS2 and EFR triggers MAPK signaling pathway that activates defense genes for antimictobial compounds. The increase in the cytosolic Ca2+ concentration is also a regulator for production of reactive oxygen species and localized programmed cell death/hypersensitive response. The secondary response is called effector-triggered immunity (ETI). Pathogens can acquire the ability to suppress PTI by directly injecting effector proteins into the plant cell through secretion systems. In addition, pathogens can manipulate plant hormone signaling pathways to evade host immune responses using coronatine toxin. Some plants possess specific intracellular surveillance proteins (R proteins) to monitor the presence of pathogen virulence proteins. This ETI occurs with localized programmed cell death to arrest pathogen growth, resulting in cultivar-specific disease resistance.
Class
Organismal Systems; Environmental adaptation
Pathway map
atri04626  Plant-pathogen interaction
atri04626

Organism
Amaranthus tricolor (tampala) [GN:atri]
Gene
130818271  calcium-dependent protein kinase 33-like [KO:K13412] [EC:2.7.11.1]
130804740  calcium-dependent protein kinase 13-like [KO:K13412] [EC:2.7.11.1]
130818928  calcium-dependent protein kinase 17-like [KO:K13412] [EC:2.7.11.1]
130805679  calcium-dependent protein kinase 26-like [KO:K13412] [EC:2.7.11.1]
130820681  calcium-dependent protein kinase 24-like [KO:K13412] [EC:2.7.11.1]
130823670  calcium-dependent protein kinase 28-like isoform X1 [KO:K13412] [EC:2.7.11.1]
130796787  calcium-dependent protein kinase 8-like [KO:K13412] [EC:2.7.11.1]
130797304  calcium-dependent protein kinase 12-like isoform X1 [KO:K13412] [EC:2.7.11.1]
130797330  calcium-dependent protein kinase 1-like [KO:K13412] [EC:2.7.11.1]
130797495  calcium-dependent protein kinase 29 isoform X1 [KO:K13412] [EC:2.7.11.1]
130826252  calcium-dependent protein kinase 20-like [KO:K13412] [EC:2.7.11.1]
130797891  calcium-dependent protein kinase 10-like [KO:K13412] [EC:2.7.11.1]
130810446  calcium-dependent protein kinase 11 [KO:K13412] [EC:2.7.11.1]
130799730  calcium-dependent protein kinase 1-like [KO:K13412] [EC:2.7.11.1]
130800033  calcium-dependent protein kinase 13-like isoform X1 [KO:K13412] [EC:2.7.11.1]
130800358  calcium-dependent protein kinase 10-like [KO:K13412] [EC:2.7.11.1]
130813314  calcium-dependent protein kinase 32-like [KO:K13412] [EC:2.7.11.1]
130828860  calcium-dependent protein kinase 33 [KO:K13412] [EC:2.7.11.1]
130828888  calcium-dependent protein kinase 17 isoform X1 [KO:K13412] [EC:2.7.11.1]
130814318  calcium-dependent protein kinase 26-like [KO:K13412] [EC:2.7.11.1]
130801575  calcium-dependent protein kinase 1-like isoform X1 [KO:K13412] [EC:2.7.11.1]
130814861  calcium-dependent protein kinase 2-like [KO:K13412] [EC:2.7.11.1]
130817282  calcium-dependent protein kinase 1-like [KO:K13412] [EC:2.7.11.1]
130804023  calcium-dependent protein kinase 24-like [KO:K13412] [EC:2.7.11.1]
130804471  calcium-dependent protein kinase 20-like isoform X1 [KO:K13412] [EC:2.7.11.1]
130817713  calcium-dependent protein kinase SK5-like isoform X1 [KO:K13412] [EC:2.7.11.1]
130820385  CDPK-related kinase 5 [KO:K13412] [EC:2.7.11.1]
130827535  CDPK-related kinase 1-like [KO:K13412] [EC:2.7.11.1]
130810203  CDPK-related kinase 3-like [KO:K13412] [EC:2.7.11.1]
130826098  CDPK-related kinase 7-like [KO:K13412] [EC:2.7.11.1]
130823703  respiratory burst oxidase homolog protein E [KO:K13447] [EC:1.6.3.- 1.11.1.-]
130798378  respiratory burst oxidase homolog protein A-like isoform X1 [KO:K13447] [EC:1.6.3.- 1.11.1.-]
130828795  respiratory burst oxidase homolog protein B-like [KO:K13447] [EC:1.6.3.- 1.11.1.-]
130801963  respiratory burst oxidase homolog protein A-like [KO:K13447] [EC:1.6.3.- 1.11.1.-]
130817352  respiratory burst oxidase homolog protein B [KO:K13447] [EC:1.6.3.- 1.11.1.-]
130818041  probable cyclic nucleotide-gated ion channel 14 [KO:K05391]
130805496  cyclic nucleotide-gated ion channel 18 [KO:K05391]
130805977  protein CNGC15b [KO:K05391]
130824525  cyclic nucleotide-gated ion channel 17-like isoform X1 [KO:K05391]
130825329  cyclic nucleotide-gated ion channel 1 [KO:K05391]
130809606  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
130800500  putative cyclic nucleotide-gated ion channel 8 isoform X1 [KO:K05391]
130814217  probable cyclic nucleotide-gated ion channel 16 [KO:K05391]
130801865  cyclic nucleotide-gated ion channel 2-like isoform X1 [KO:K05391]
130814710  cyclic nucleotide-gated ion channel 17-like isoform X1 [KO:K05391]
130815463  probable cyclic nucleotide-gated ion channel 20, chloroplastic [KO:K05391]
130804195  putative cyclic nucleotide-gated ion channel 8 [KO:K05391]
130804292  cyclic nucleotide-gated ion channel 2-like isoform X1 [KO:K05391]
130804484  probable cyclic nucleotide-gated ion channel 5 isoform X1 [KO:K05391]
130807297  cyclic nucleotide-gated ion channel 4 [KO:K05391]
130805426  calmodulin-7 isoform X1 [KO:K02183]
130806877  calmodulin-7 [KO:K02183]
130809101  probable calcium-binding protein CML45 [KO:K02183]
130825277  calcium-binding protein CP1 [KO:K02183]
130826072  calmodulin [KO:K02183]
130799991  calmodulin-2/4 [KO:K02183]
130828264  calmodulin isoform X1 [KO:K02183]
130819717  calmodulin-like protein 3 [KO:K13448]
130820357  calmodulin-like protein 30 [KO:K13448]
130820944  caltractin-like isoform X1 [KO:K13448]
130821042  probable calcium-binding protein CML15 [KO:K13448]
130821544  LOW QUALITY PROTEIN: probable calcium-binding protein CML18 [KO:K13448]
130806972  probable calcium-binding protein CML13 [KO:K13448]
130807427  probable calcium-binding protein CML15 [KO:K13448]
130823572  probable calcium-binding protein CML18 [KO:K13448]
130808775  probable calcium-binding protein CML41 [KO:K13448]
130825382  probable calcium-binding protein CML13 [KO:K13448]
130809435  probable calcium-binding protein CML43 [KO:K13448]
130810004  probable calcium-binding protein CML44 [KO:K13448]
130826000  probable calcium-binding protein CML36 [KO:K13448]
130826120  calcium-binding protein CBP-like [KO:K13448]
130826121  calcium-binding protein CBP-like [KO:K13448]
130810517  calcium-binding allergen Ole e 8-like [KO:K13448]
130826636  probable calcium-binding protein CML36 [KO:K13448]
130812584  probable calcium-binding protein CML48 isoform X1 [KO:K13448]
130800217  calmodulin-like protein 3 [KO:K13448]
130800436  probable calcium-binding protein CML15 [KO:K13448]
130813058  probable calcium-binding protein CML44 [KO:K13448]
130813511  calcium-binding protein CBP-like [KO:K13448]
130813521  calcium-binding protein CBP-like [KO:K13448]
130814275  caltractin [KO:K13448]
130802127  probable calcium-binding protein CML13 [KO:K13448]
130802655  polcalcin Che a 3 [KO:K13448]
130803269  probable calcium-binding protein CML18 [KO:K13448]
130803628  probable calcium-binding protein CML25 [KO:K13448]
130803892  polcalcin Che a 3-like [KO:K13448]
130804108  probable calcium-binding protein CML13 [KO:K13448]
130823662  putative nitric oxide synthase [KO:K13427] [EC:1.14.13.39]
130799498  mitogen-activated protein kinase homolog MMK2-like [KO:K20600] [EC:2.7.11.24]
130811351  mitogen-activated protein kinase homolog MMK2 isoform X1 [KO:K20600] [EC:2.7.11.24]
130824180  LRR receptor-like serine/threonine-protein kinase FLS2 [KO:K13420] [EC:2.7.11.1]
130814507  LRR receptor-like serine/threonine-protein kinase FLS2 [KO:K13420] [EC:2.7.11.1]
130810588  BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1-like [KO:K13416] [EC:2.7.10.1 2.7.11.1]
130811108  BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1-like [KO:K13416] [EC:2.7.10.1 2.7.11.1]
130798162  elongation factor Tu, chloroplastic-like [KO:K02358]
130800232  elongation factor Tu, chloroplastic-like [KO:K02358]
130804154  elongation factor Tu, mitochondrial-like [KO:K02358]
130811142  mitogen-activated protein kinase kinase kinase 1-like [KO:K13414] [EC:2.7.11.25]
130802691  mitogen-activated protein kinase kinase kinase 1-like isoform X1 [KO:K13414] [EC:2.7.11.25]
130814208  mitogen-activated protein kinase kinase 6 [KO:K04368] [EC:2.7.12.2]
130814840  mitogen-activated protein kinase kinase 5-like [KO:K13413] [EC:2.7.12.2]
130805509  mitogen-activated protein kinase 3-like [KO:K20536] [EC:2.7.11.24]
130806019  mitogen-activated protein kinase 3 [KO:K20536] [EC:2.7.11.24]
130825108  mitogen-activated protein kinase homolog MMK1-like [KO:K14512] [EC:2.7.11.24]
130825546  mitogen-activated protein kinase homolog MMK1 [KO:K14512] [EC:2.7.11.24]
130827803  probable WRKY transcription factor 33 [KO:K13424]
130812877  probable WRKY transcription factor 25 [KO:K13424]
130814159  probable WRKY transcription factor 33 [KO:K13424]
130811366  WRKY transcription factor 22 [KO:K13425]
130799679  WRKY transcription factor 22-like [KO:K13425]
130801746  WRKY transcription factor 22-like isoform X1 [KO:K13426]
130812606  glycerol kinase [KO:K00864] [EC:2.7.1.30]
130820861  pathogenesis-related protein 1-like [KO:K13449]
130806420  pathogenesis-related protein 1B-like [KO:K13449]
130821566  pathogenesis-related protein PRB1-3-like [KO:K13449]
130822865  pathogenesis-related protein 1-like [KO:K13449]
130823780  pathogenesis-related protein PR-1-like [KO:K13449]
130825679  pathogenesis-related protein PR-1 type-like [KO:K13449]
130813177  pathogenesis-related protein 1A-like [KO:K13449]
130813212  pathogenesis-related protein PR-1 type-like [KO:K13449]
130813223  pathogenesis-related protein 1A-like [KO:K13449]
130804618  pto-interacting protein 1 [KO:K13436] [EC:2.7.11.1]
130825872  PTI1-like tyrosine-protein kinase 1 isoform X1 [KO:K13436] [EC:2.7.11.1]
130800521  pto-interacting protein 1-like isoform X1 [KO:K13436] [EC:2.7.11.1]
130804053  PTI1-like tyrosine-protein kinase 3 [KO:K13436] [EC:2.7.11.1]
130804072  pto-interacting protein 1-like [KO:K13436] [EC:2.7.11.1]
130825495  RPM1-interacting protein 4-like isoform X1 [KO:K13456]
130813069  RPM1-interacting protein 4-like [KO:K13456]
130797348  putative disease resistance RPP13-like protein 3 [KO:K13457]
130797805  disease resistance protein RPM1-like [KO:K13457]
130815276  disease resistance protein RPM1-like [KO:K13457]
130825396  cysteine and histidine-rich domain-containing protein RAR1 [KO:K13458]
130806242  protein SGT1 homolog B-like [KO:K12795]
130805879  heat shock protein 90-6, mitochondrial [KO:K09487]
130821081  heat shock protein 90-5, chloroplastic [KO:K09487]
130810196  endoplasmin homolog [KO:K09487]
130798961  endoplasmin homolog [KO:K09487]
130806561  heat shock protein 83-like [KO:K04079]
130808031  heat shock cognate protein 80 [KO:K04079]
130808033  heat shock cognate protein 80-like [KO:K04079]
130825886  heat shock protein 83 [KO:K04079]
130806603  disease resistance protein At4g27190-like isoform X1 [KO:K13459]
130807822  disease resistance protein SUMM2-like [KO:K13459]
130807828  disease resistance protein SUMM2-like [KO:K13459]
130807860  disease resistance protein SUMM2-like [KO:K13459]
130807948  disease resistance protein SUMM2-like [KO:K13459]
130807949  disease resistance protein SUMM2-like [KO:K13459]
130809165  disease resistance protein SUMM2-like isoform X1 [KO:K13459]
130825127  probable disease resistance protein At4g27220 [KO:K13459]
130809481  disease resistance protein At4g27190-like [KO:K13459]
130826049  disease resistance protein At4g27190-like isoform X1 [KO:K13459]
130815744  probable disease resistance protein At1g61300 [KO:K13459]
130815969  LOW QUALITY PROTEIN: disease resistance protein RPS2-like [KO:K13459]
130820588  serine/threonine-protein kinase PBS1-like [KO:K13430] [EC:2.7.11.1]
130823729  probable serine/threonine-protein kinase PBL7 isoform X1 [KO:K13430] [EC:2.7.11.1]
130807911  serine/threonine-protein kinase PBS1-like [KO:K13430] [EC:2.7.11.1]
130800328  protein EDS1L-like [KO:K18875]
130824226  cysteine protease RD19A-like [KO:K01373] [EC:3.4.22.41]
130811529  cysteine protease RD19A-like [KO:K01373] [EC:3.4.22.41]
130815666  probable cysteine protease RD19D [KO:K01373] [EC:3.4.22.41]
130804686  3-ketoacyl-CoA synthase 19-like [KO:K15397] [EC:2.3.1.199]
130806481  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
130823401  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
130807007  3-ketoacyl-CoA synthase 5-like [KO:K15397] [EC:2.3.1.199]
130807008  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
130807009  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
130807476  3-ketoacyl-CoA synthase 5-like [KO:K15397] [EC:2.3.1.199]
130823961  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
130824038  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
130798021  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
130798254  3-ketoacyl-CoA synthase 10-like [KO:K15397] [EC:2.3.1.199]
130810998  3-ketoacyl-CoA synthase 1 [KO:K15397] [EC:2.3.1.199]
130812906  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
130827816  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
130813257  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
130828782  3-ketoacyl-CoA synthase 7-like [KO:K15397] [EC:2.3.1.199]
130828881  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
130801173  3-ketoacyl-CoA synthase 10 [KO:K15397] [EC:2.3.1.199]
130814177  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
130801599  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
130802298  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
130814880  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
130802398  3-ketoacyl-CoA synthase 19-like [KO:K15397] [EC:2.3.1.199]
130803272  3-ketoacyl-CoA synthase 17-like [KO:K15397] [EC:2.3.1.199]
130804296  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
130806073  WRKY transcription factor 1-like [KO:K18834]
130805406  receptor-like protein EIX2 [KO:K13466]
130805853  receptor-like protein EIX2 [KO:K13466]
130800044  chitin elicitor receptor kinase 1-like [KO:K13429]
130814175  lysM domain receptor-like kinase 3 isoform X1 [KO:K13429]
130804230  chitin elicitor receptor kinase 1-like [KO:K13429]
Compound
C00027  Hydrogen peroxide
C00076  Calcium cation
C00533  Nitric oxide
C00704  Superoxide
C16844  Hydroxyl radical
Reference
PMID:18206360
  Authors
Zipfel C
  Title
Pattern-recognition receptors in plant innate immunity.
  Journal
Curr Opin Immunol 20:10-6 (2008)
DOI:10.1016/j.coi.2007.11.003
Reference
PMID:19748302
  Authors
Chinchilla D, Shan L, He P, de Vries S, Kemmerling B
  Title
One for all: the receptor-associated kinase BAK1.
  Journal
Trends Plant Sci 14:535-41 (2009)
DOI:10.1016/j.tplants.2009.08.002
Reference
PMID:19423812
  Authors
Boller T, He SY
  Title
Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogens.
  Journal
Science 324:742-4 (2009)
DOI:10.1126/science.1171647
Reference
PMID:19794842
  Authors
Ma W, Smigel A, Verma R, Berkowitz GA
  Title
Cyclic nucleotide gated channels and related signaling components in plant innate immunity.
  Journal
Plant Signal Behav 4:277-82 (2009)
DOI:10.4161/psb.4.4.8103
Reference
PMID:11875555
  Authors
Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J
  Title
MAP kinase signalling cascade in Arabidopsis innate immunity.
  Journal
Nature 415:977-83 (2002)
DOI:10.1038/415977a
Reference
PMID:15922649
  Authors
Zipfel C, Felix G
  Title
Plants and animals: a different taste for microbes?
  Journal
Curr Opin Plant Biol 8:353-60 (2005)
DOI:10.1016/j.pbi.2005.05.004
Reference
PMID:17451411
  Authors
He P, Shan L, Sheen J
  Title
Elicitation and suppression of microbe-associated molecular pattern-triggered immunity in plant-microbe interactions.
  Journal
Cell Microbiol 9:1385-96 (2007)
DOI:10.1111/j.1462-5822.2007.00944.x
Reference
PMID:17876517
  Authors
de Wit PJ
  Title
How plants recognize pathogens and defend themselves.
  Journal
Cell Mol Life Sci 64:2726-32 (2007)
DOI:10.1007/s00018-007-7284-7
Reference
PMID:16497589
  Authors
Chisholm ST, Coaker G, Day B, Staskawicz BJ
  Title
Host-microbe interactions: shaping the evolution of the plant immune response.
  Journal
Cell 124:803-14 (2006)
DOI:10.1016/j.cell.2006.02.008
Reference
PMID:16677430
  Authors
McHale L, Tan X, Koehl P, Michelmore RW
  Title
Plant NBS-LRR proteins: adaptable guards.
  Journal
Genome Biol 7:212 (2006)
DOI:10.1186/gb-2006-7-4-212
Reference
PMID:11459065
  Authors
Dangl JL, Jones JD
  Title
Plant pathogens and integrated defence responses to infection.
  Journal
Nature 411:826-33 (2001)
DOI:10.1038/35081161
Reference
PMID:17108957
  Authors
Jones JD, Dangl JL
  Title
The plant immune system.
  Journal
Nature 444:323-9 (2006)
DOI:10.1038/nature05286
Reference
PMID:16697674
  Authors
da Cunha L, McFall AJ, Mackey D
  Title
Innate immunity in plants: a continuum of layered defenses.
  Journal
Microbes Infect 8:1372-81 (2006)
DOI:10.1016/j.micinf.2005.12.018
Reference
PMID:15862106
  Authors
Mudgett MB
  Title
New insights to the function of phytopathogenic bacterial type III effectors in plants.
  Journal
Annu Rev Plant Biol 56:509-31 (2005)
DOI:10.1146/annurev.arplant.56.032604.144218
Reference
PMID:17714518
  Authors
Ma W, Berkowitz GA
  Title
The grateful dead: calcium and cell death in plant innate immunity.
  Journal
Cell Microbiol 9:2571-85 (2007)
DOI:10.1111/j.1462-5822.2007.01031.x
Reference
PMID:14711430
  Authors
Schulze-Lefert P
  Title
Plant immunity: the origami of receptor activation.
  Journal
Curr Biol 14:R22-4 (2004)
DOI:10.1016/j.cub.2003.12.017
Reference
PMID:9868361
  Authors
Van der Biezen EA, Jones JD
  Title
Plant disease-resistance proteins and the gene-for-gene concept.
  Journal
Trends Biochem Sci 23:454-6 (1998)
DOI:10.1016/S0968-0004(98)01311-5
Reference
PMID:16936700
  Authors
Abramovitch RB, Anderson JC, Martin GB
  Title
Bacterial elicitation and evasion of plant innate immunity.
  Journal
Nat Rev Mol Cell Biol 7:601-11 (2006)
DOI:10.1038/nrm1984
Related
pathway
atri04144  Endocytosis
KO pathway
ko04626   
LinkDB

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