KEGG   PATHWAY: aus00630
Entry
aus00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Austwickia sp. Fred_18-Q3-R57-64_BATAC.85v2
Class
Metabolism; Carbohydrate metabolism
Pathway map
aus00630  Glyoxylate and dicarboxylate metabolism
aus00630

Module
aus_M00621  Glycine cleavage system [PATH:aus00630]
Other DBs
GO: 0046487 0043648
Organism
Austwickia sp. Fred_18-Q3-R57-64_BATAC.85v2 [GN:aus]
Gene
IPK37_03465  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
IPK37_13055  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
IPK37_07855  malate synthase G [KO:K01638] [EC:2.3.3.9]
IPK37_02370  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
IPK37_03265  helix-turn-helix domain-containing protein [KO:K01647] [EC:2.3.3.1]
IPK37_05245  citrate synthase [KO:K01647] [EC:2.3.3.1]
IPK37_06230  citrate synthase [KO:K01647] [EC:2.3.3.1]
IPK37_12160  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
IPK37_18730  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
IPK37_01615  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
IPK37_05150  thiolase family protein [KO:K00626] [EC:2.3.1.9]
IPK37_08455  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
IPK37_09670  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
IPK37_13805  3-oxoacyl-ACP reductase FabG [KO:K00023] [EC:1.1.1.36]
IPK37_16815  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
IPK37_01620  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
IPK37_01675  protein meaA [KO:K14447] [EC:5.4.99.63]
IPK37_14060  MaoC family dehydratase [KO:K14449] [EC:4.2.1.148]
IPK37_13860  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
IPK37_02175  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
IPK37_02115  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
IPK37_02290  acyl-CoA mutase large subunit family protein [KO:K01848] [EC:5.4.99.2]
IPK37_15475  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
IPK37_05400  catalase [KO:K03781] [EC:1.11.1.6]
IPK37_10070  catalase [KO:K03781] [EC:1.11.1.6]
IPK37_16645  catalase [KO:K03781] [EC:1.11.1.6]
IPK37_10320  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
IPK37_07255  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
IPK37_18430  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
IPK37_18465  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
IPK37_11005  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
IPK37_17155  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
IPK37_18370  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
IPK37_14050  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
IPK37_18385  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
IPK37_17130  gcvH; glycine cleavage system protein GcvH [KO:K02437]
IPK37_06100  garR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
IPK37_02795  glycerate kinase [KO:K00865] [EC:2.7.1.165]
IPK37_19155  glycerate kinase [KO:K00865] [EC:2.7.1.165]
IPK37_03670  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
IPK37_01925  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
IPK37_11815  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
IPK37_11835  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
IPK37_11810  4Fe-4S dicluster domain-containing protein [KO:K00124]
IPK37_11080  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
aus00010  Glycolysis / Gluconeogenesis
aus00020  Citrate cycle (TCA cycle)
aus00030  Pentose phosphate pathway
aus00053  Ascorbate and aldarate metabolism
aus00071  Fatty acid degradation
aus00230  Purine metabolism
aus00250  Alanine, aspartate and glutamate metabolism
aus00260  Glycine, serine and threonine metabolism
aus00620  Pyruvate metabolism
aus00710  Carbon fixation by Calvin cycle
aus00750  Vitamin B6 metabolism
aus00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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