KEGG   PATHWAY: bct00230
Entry
bct00230                    Pathway                                
Name
Purine metabolism - Burkholderia cepacia GG4
Class
Metabolism; Nucleotide metabolism
Pathway map
bct00230  Purine metabolism
bct00230

Module
bct_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bct00230]
bct_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bct00230]
bct_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bct00230]
bct_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bct00230]
bct_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bct00230]
bct_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bct00230]
bct_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bct00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia cepacia GG4 [GN:bct]
Gene
GEM_1177  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
GEM_2630  Phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
GEM_0637  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
GEM_4796  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
GEM_1115  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
GEM_0920  PurN protein [KO:K11175] [EC:2.1.2.2]
GEM_1087  phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
GEM_1513  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
GEM_2764  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
GEM_0810  Phosphoribosylaminoimidazole Carboxylase, Atpase Subunit [KO:K01589] [EC:6.3.4.18]
GEM_0809  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
GEM_0808  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
GEM_2855  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
GEM_2832  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
GEM_0657  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
GEM_5369  stationary-phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
GEM_1603  stationary-phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
GEM_3912  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
GEM_1634  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
GEM_2930  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
GEM_1449  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
GEM_1611  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
GEM_2531  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
GEM_2697  FAD-binding molybdopterin dehydrogenase [KO:K13481] [EC:1.17.1.4]
GEM_2696  xanthine dehydrogenase, molybdenum binding subunit apoprotein / xanthine oxidase [KO:K13482] [EC:1.17.1.4]
GEM_4182  (2Fe-2S)-binding domain protein [KO:K13483]
GEM_0066  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
GEM_1451  GMP synthase, large subunit [KO:K01951] [EC:6.3.5.2]
GEM_2252  putative amidotransferase [KO:K01951] [EC:6.3.5.2]
GEM_2502  guanine deaminase [KO:K01487] [EC:3.5.4.3]
GEM_2528  Guanylate kinase [KO:K00942] [EC:2.7.4.8]
GEM_2925  Ribonucleotide reductase of class Ia (aerobic),alpha subunit [KO:K00525] [EC:1.17.4.1]
GEM_2924  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
GEM_3127  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
GEM_2526  (p)ppGpp synthetase I SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
GEM_2146  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
GEM_1959  GTP pyrophosphokinase ppGpp synthetase I [KO:K00951] [EC:2.7.6.5]
GEM_1625  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
GEM_2921  PfkB domain protein [KO:K00856] [EC:2.7.1.20]
GEM_4883  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
GEM_2501  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
GEM_0535  2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
GEM_0882  adenylate kinase [KO:K00939] [EC:2.7.4.3]
GEM_2260  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
GEM_2656  bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
GEM_1235  bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
GEM_0957  translation elongation factor Tu [KO:K00956] [EC:2.7.7.4]
GEM_0956  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
GEM_1236  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
GEM_1467  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
GEM_2601  putative transthyretin-like protein [KO:K07127] [EC:3.5.2.17]
GEM_2602  transthyretin family protein [KO:K07127] [EC:3.5.2.17]
GEM_2605  Pucl protein [KO:K13485] [EC:4.1.1.97]
GEM_1462  urate oxidase [KO:K13485] [EC:4.1.1.97]
GEM_1460  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
GEM_4595  putative Asp/Glu/Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
GEM_1461  urate catabolism protein [KO:K16842] [EC:3.5.2.5]
GEM_1463  allantoicase [KO:K01477] [EC:3.5.3.4]
GEM_2874  allantoicase [KO:K01477] [EC:3.5.3.4]
GEM_5758  allantoin catabolism protein [KO:K14977] [EC:3.5.3.26]
GEM_1464  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
GEM_2873  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
GEM_5701  5-carboxymethyl-2-hydroxymuconate Delta-isomerase [KO:K16856] [EC:4.3.2.3]
GEM_2623  UreC protein [KO:K01428] [EC:3.5.1.5]
GEM_2622  urease subunit beta [KO:K01429] [EC:3.5.1.5]
GEM_2621  urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bct00030  Pentose phosphate pathway
bct00220  Arginine biosynthesis
bct00250  Alanine, aspartate and glutamate metabolism
bct00260  Glycine, serine and threonine metabolism
bct00340  Histidine metabolism
bct00630  Glyoxylate and dicarboxylate metabolism
bct00730  Thiamine metabolism
bct00740  Riboflavin metabolism
bct00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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