KEGG   PATHWAY: bmaz00230
Entry
bmaz00230                   Pathway                                
Name
Purine metabolism - Burkholderia mallei NCTC 10247
Class
Metabolism; Nucleotide metabolism
Pathway map
bmaz00230  Purine metabolism
bmaz00230

Module
bmaz_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bmaz00230]
bmaz_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bmaz00230]
bmaz_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bmaz00230]
bmaz_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bmaz00230]
bmaz_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bmaz00230]
bmaz_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bmaz00230]
bmaz_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bmaz00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia mallei NCTC 10247 [GN:bmaz]
Gene
BM44_2583  NUDIX domain protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BM44_1163  phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III family protein [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BM44_416  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BM44_3227  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BM44_2650  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BM44_1119  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BM44_2682  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
BM44_1896  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BM44_1045  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BM44_2927  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
BM44_2928  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
BM44_2929  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BM44_691  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BM44_769  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BM44_396  phosphoribosyl transferase domain protein [KO:K00759] [EC:2.4.2.7]
BM44_1979  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BM44_2010  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BM44_101  phosphoribosyl transferase domain protein [KO:K00760] [EC:2.4.2.8]
BM44_1828  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BM44_1987  nucleoside diphosphate kinase family protein [KO:K00940] [EC:2.7.4.6]
BM44_1249  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
BM44_1307  xdhA; xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
BM44_1308  xdhB; xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BM44_1830  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
BM44_370  peptidase C26 family protein [KO:K01951] [EC:6.3.5.2]
BM44_2823  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
BM44_1252  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
BM44_96  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
BM44_3735  ribonucleotide reductase, barrel domain protein [KO:K00525] [EC:1.17.4.1]
BM44_95  ribonucleotide reductase, small chain family protein [KO:K00526] [EC:1.17.4.1]
BM44_1489  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
BM44_539  dgt; dGTPase family protein [KO:K01129] [EC:3.1.5.1]
BM44_1254  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BM44_2449  ppx/GppA phosphatase family protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BM44_2125  RelA/SpoT family protein [KO:K00951] [EC:2.7.6.5]
BM44_825  response regulator [KO:K01768] [EC:4.6.1.1]
BM44_2001  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BM44_91  pfkB carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
BM44_3387  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BM44_2821  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BM44_167  cpdB; 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BM44_1086  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
BM44_2526  calcineurin-like phosphoesterase family protein [KO:K03651] [EC:3.1.4.53]
BM44_1349  apaH; apaH [KO:K01525] [EC:3.6.1.41]
BM44_1496  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BM44_1721  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BM44_3519  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BM44_1518  cysN; sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
BM44_1517  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BM44_1738  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BM44_1843  uraD; OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
BM44_1841  asp/Glu/Hydantoin racemase family protein [KO:K16841] [EC:5.1.99.3]
BM44_1842  polysaccharide deacetylase family protein [KO:K16842] [EC:3.5.2.5]
BM44_1844  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BM44_673  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BM44_1846  ureidoglycolate hydrolase family protein [KO:K01483] [EC:4.3.2.3]
BM44_675  ureidoglycolate hydrolase family protein [KO:K01483] [EC:4.3.2.3]
BM44_3333  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
BM44_1170  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
BM44_1171  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BM44_1172  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
BM44_2167  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bmaz00030  Pentose phosphate pathway
bmaz00220  Arginine biosynthesis
bmaz00250  Alanine, aspartate and glutamate metabolism
bmaz00260  Glycine, serine and threonine metabolism
bmaz00340  Histidine metabolism
bmaz00630  Glyoxylate and dicarboxylate metabolism
bmaz00730  Thiamine metabolism
bmaz00740  Riboflavin metabolism
bmaz00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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