KEGG   PATHWAY: bum00630
Entry
bum00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia sp. PAMC 26561
Class
Metabolism; Carbohydrate metabolism
Pathway map
bum00630  Glyoxylate and dicarboxylate metabolism
bum00630

Module
bum_M00012  Glyoxylate cycle [PATH:bum00630]
bum_M00621  Glycine cleavage system [PATH:bum00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia sp. PAMC 26561 [GN:bum]
Gene
AXG89_11775  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
AXG89_19185  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
AXG89_15415  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
AXG89_05490  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
AXG89_15385  malate synthase G [KO:K01638] [EC:2.3.3.9]
AXG89_19960  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
AXG89_40010  citrate synthase [KO:K01647] [EC:2.3.3.1]
AXG89_20000  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
AXG89_19935  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
AXG89_28045  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
AXG89_32275  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
AXG89_22840  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
AXG89_24275  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AXG89_14725  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AXG89_18710  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AXG89_13165  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AXG89_14100  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AXG89_14130  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AXG89_06625  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AXG89_28415  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AXG89_14125  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
AXG89_08290  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
AXG89_08285  glcE; glycolate oxidase [KO:K11472] [EC:1.1.99.14]
AXG89_08280  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
AXG89_34090  caspase [KO:K03781] [EC:1.11.1.6]
AXG89_35200  catalase [KO:K03781] [EC:1.11.1.6]
AXG89_28845  catalase [KO:K03781] [EC:1.11.1.6]
AXG89_18235  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
AXG89_08255  catalase [KO:K03781] [EC:1.11.1.6]
AXG89_23845  catalase [KO:K03781] [EC:1.11.1.6]
AXG89_39510  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
AXG89_17905  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
AXG89_06560  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
AXG89_01155  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
AXG89_13870  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
AXG89_41055  hypothetical protein [KO:K01091] [EC:3.1.3.18]
AXG89_01110  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
AXG89_03655  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
AXG89_35975  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
AXG89_11245  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AXG89_02995  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AXG89_19750  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AXG89_05470  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
AXG89_37595  glycine dehydrogenase [KO:K00282] [EC:1.4.4.2]
AXG89_37590  glycine dehydrogenase [KO:K00283] [EC:1.4.4.2]
AXG89_05460  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
AXG89_17475  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
AXG89_11310  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
AXG89_14830  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
AXG89_05465  glycine cleavage system protein H [KO:K02437]
AXG89_12535  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
AXG89_12530  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
AXG89_15860  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
AXG89_13075  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
AXG89_12805  glycerate kinase [KO:K00865] [EC:2.7.1.165]
AXG89_13805  aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
AXG89_38910  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
AXG89_18875  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
AXG89_08565  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
AXG89_36570  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
AXG89_01580  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
AXG89_01575  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
AXG89_01570  formate dehydrogenase [KO:K00124]
AXG89_01565  formate dehydrogenase [KO:K00127]
AXG89_32005  hypothetical protein [KO:K01432] [EC:3.5.1.9]
AXG89_18855  kynurenine formamidase [KO:K07130] [EC:3.5.1.9]
AXG89_07410  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
AXG89_19800  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
AXG89_22165  amiF; formamidase [KO:K01455] [EC:3.5.1.49]
AXG89_09415  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
AXG89_35845  oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bum00010  Glycolysis / Gluconeogenesis
bum00020  Citrate cycle (TCA cycle)
bum00030  Pentose phosphate pathway
bum00053  Ascorbate and aldarate metabolism
bum00071  Fatty acid degradation
bum00230  Purine metabolism
bum00250  Alanine, aspartate and glutamate metabolism
bum00260  Glycine, serine and threonine metabolism
bum00620  Pyruvate metabolism
bum00710  Carbon fixation by Calvin cycle
bum00750  Vitamin B6 metabolism
bum00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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