KEGG   PATHWAY: bum00230
Entry
bum00230                    Pathway                                
Name
Purine metabolism - Burkholderia sp. PAMC 26561
Class
Metabolism; Nucleotide metabolism
Pathway map
bum00230  Purine metabolism
bum00230

Module
bum_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bum00230]
bum_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bum00230]
bum_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bum00230]
bum_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bum00230]
bum_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bum00230]
bum_M00546  Purine degradation, xanthine => urea [PATH:bum00230]
bum_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bum00230]
bum_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bum00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia sp. PAMC 26561 [GN:bum]
Gene
AXG89_00220  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
AXG89_01800  phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
AXG89_07300  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
AXG89_20100  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
AXG89_10990  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
AXG89_09345  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
AXG89_10845  phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
AXG89_13120  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
AXG89_08415  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
AXG89_08985  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
AXG89_08980  N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
AXG89_08975  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
AXG89_08610  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
AXG89_08095  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
AXG89_07395  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
AXG89_07850  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
AXG89_14290  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AXG89_14740  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AXG89_35325  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
AXG89_14140  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
AXG89_38745  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
AXG89_03290  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
AXG89_12070  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
AXG89_14255  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
AXG89_10025  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
AXG89_39995  FAD-binding molybdopterin dehydrogenase [KO:K13481] [EC:1.17.1.4]
AXG89_10205  FAD-binding molybdopterin dehydrogenase [KO:K13481] [EC:1.17.1.4]
AXG89_39990  aldehyde oxidase [KO:K13482] [EC:1.17.1.4]
AXG89_10200  aldehyde oxidase [KO:K13482] [EC:1.17.1.4]
AXG89_35030  dehydrogenase [KO:K11177] [EC:1.17.1.4]
AXG89_23530  hypothetical protein [KO:K11177] [EC:1.17.1.4]
AXG89_29155  hypothetical protein [KO:K11177] [EC:1.17.1.4]
AXG89_18290  acylaldehyde oxidase [KO:K11177] [EC:1.17.1.4]
AXG89_35035  molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
AXG89_22950  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
AXG89_18285  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
AXG89_29730  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
AXG89_35040  aldehyde oxidoreductase [KO:K13483]
AXG89_22955  hypothetical protein [KO:K13483]
AXG89_23520  (2Fe-2S)-binding protein [KO:K13483]
AXG89_29165  (2Fe-2S)-binding protein [KO:K13483]
AXG89_18280  (2Fe-2S)-binding protein [KO:K13483]
AXG89_29725  hypothetical protein [KO:K13483]
AXG89_12080  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
AXG89_05700  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
AXG89_29920  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
AXG89_20885  guanine deaminase [KO:K01487] [EC:3.5.4.3]
AXG89_10180  guanine deaminase [KO:K01487] [EC:3.5.4.3]
AXG89_10045  guanylate kinase [KO:K00942] [EC:2.7.4.8]
AXG89_03265  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
AXG89_17395  ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
AXG89_03250  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
AXG89_04125  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
AXG89_10055  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
AXG89_00760  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
AXG89_15110  GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
AXG89_14185  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
AXG89_03235  sugar kinase [KO:K00856] [EC:2.7.1.20]
AXG89_20290  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
AXG89_10190  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
AXG89_02790  adenylate kinase [KO:K00939] [EC:2.7.4.3]
AXG89_35355  metallophosphatase [KO:K03651] [EC:3.1.4.53]
AXG89_16120  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
AXG89_16740  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
AXG89_02450  bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
AXG89_16205  adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
AXG89_09570  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
AXG89_09565  sulfate adenylyltransferase [KO:K00957] [EC:2.7.7.4]
AXG89_36750  FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
AXG89_12255  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
AXG89_12235  OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
AXG89_12225  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
AXG89_12230  allantoinase [KO:K16842] [EC:3.5.2.5]
AXG89_12240  allantoicase [KO:K01477] [EC:3.5.3.4]
AXG89_12245  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
AXG89_19565  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
AXG89_01755  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
AXG89_01750  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
AXG89_01745  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
AXG89_05370  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bum00030  Pentose phosphate pathway
bum00220  Arginine biosynthesis
bum00250  Alanine, aspartate and glutamate metabolism
bum00260  Glycine, serine and threonine metabolism
bum00340  Histidine metabolism
bum00630  Glyoxylate and dicarboxylate metabolism
bum00730  Thiamine metabolism
bum00740  Riboflavin metabolism
bum00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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