KEGG   PATHWAY: cam00053
Entry
cam00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Cicer arietinum (chickpea)
Class
Metabolism; Carbohydrate metabolism
Pathway map
cam00053  Ascorbate and aldarate metabolism
cam00053

Module
cam_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:cam00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Cicer arietinum (chickpea) [GN:cam]
Gene
101506476  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
101497812  UDP-glucose 6-dehydrogenase 2 [KO:K00012] [EC:1.1.1.22]
101506820  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
101490955  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
101505137  UDP-sugar pyrophospharylase [KO:K12447] [EC:2.7.7.64]
101503341  glucuronokinase 1 [KO:K16190] [EC:2.7.1.43]
101493267  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
101492445  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
101495650  aldo-keto reductase family 4 member C8-like [KO:K00002] [EC:1.1.1.2]
101510508  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
101504247  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
101488690  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
101499451  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
101508626  aldose reductase [KO:K00002] [EC:1.1.1.2]
101498426  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
101505780  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
101495962  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
101507144  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
101497510  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
101501356  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
101510212  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
101497835  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
101496687  inositol-phosphate phosphatase-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
101502853  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
101495571  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
101498593  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
101500778  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
101501100  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
101501565  UDP-glucuronate 4-epimerase 2-like [KO:K08679] [EC:5.1.3.6]
101500840  UDP-glucuronate 4-epimerase 5 [KO:K08679] [EC:5.1.3.6]
101489756  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
101503692  probable monodehydroascorbate reductase, cytoplasmic isoform 2 [KO:K08232] [EC:1.6.5.4]
101489296  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
101515028  monodehydroascorbate reductase, chloroplastic [KO:K08232] [EC:1.6.5.4]
101497868  peroxidase; putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
101497640  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
101496561  L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
101511999  peroxidase; probable L-ascorbate peroxidase 6, chloroplastic [KO:K00434] [EC:1.11.1.11]
101507560  L-ascorbate peroxidase 3, peroxisomal-like [KO:K00434] [EC:1.11.1.11]
101496317  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
101503639  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
101511136  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
101514709  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
101514053  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
101495562  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
101490532  aldehyde dehydrogenase family 2 member B7, mitochondrial [KO:K00128] [EC:1.2.1.3]
101491914  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
101492709  aldehyde dehydrogenase family 2 member B7, mitochondrial [KO:K00128] [EC:1.2.1.3]
101497113  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
101505038  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
101515558  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
101510937  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
101511680  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
101511819  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
101513733  aldehyde dehydrogenase family 7 member A1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
cam00020  Citrate cycle (TCA cycle)
cam00040  Pentose and glucuronate interconversions
cam00051  Fructose and mannose metabolism
cam00520  Amino sugar and nucleotide sugar metabolism
cam00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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