KEGG   PATHWAY: ceh00630
Entry
ceh00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Celeribacter ethanolicus
Class
Metabolism; Carbohydrate metabolism
Pathway map
ceh00630  Glyoxylate and dicarboxylate metabolism
ceh00630

Module
ceh_M00373  Ethylmalonyl pathway [PATH:ceh00630]
ceh_M00621  Glycine cleavage system [PATH:ceh00630]
ceh_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:ceh00630]
Other DBs
GO: 0046487 0043648
Organism
Celeribacter ethanolicus [GN:ceh]
Gene
CEW89_01060  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
CEW89_10240  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
CEW89_07685  malate synthase G [KO:K01638] [EC:2.3.3.9]
CEW89_10115  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
CEW89_06920  type II citrate synthase [KO:K01647] [EC:2.3.3.1]
CEW89_06650  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
CEW89_06645  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
CEW89_10990  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CEW89_05630  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CEW89_18495  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CEW89_17085  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CEW89_10995  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
CEW89_09200  (R)-hydratase [KO:K17865] [EC:4.2.1.55]
CEW89_10025  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
CEW89_18165  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
CEW89_10030  protein meaA [KO:K14447] [EC:5.4.99.63]
CEW89_14850  acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
CEW89_10085  hypothetical protein [KO:K14449] [EC:4.2.1.148]
CEW89_10920  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
CEW89_10100  CoA ester lyase [KO:K14451] [EC:3.1.2.30]
CEW89_19210  acetyl/propionyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
CEW89_19180  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
CEW89_19225  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
CEW89_16250  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
CEW89_16255  2-hydroxy-acid oxidase [KO:K11472] [EC:1.1.99.14]
CEW89_16260  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
CEW89_09840  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
CEW89_16530  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
CEW89_07560  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
CEW89_19395  phosphatase [KO:K01091] [EC:3.1.3.18]
CEW89_15275  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
CEW89_09390  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
CEW89_08275  aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
CEW89_06600  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CEW89_08025  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CEW89_08035  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CEW89_04105  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CEW89_15810  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CEW89_18410  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CEW89_16620  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
CEW89_16610  gcvT; glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
CEW89_17230  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
CEW89_17315  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
CEW89_10160  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CEW89_06780  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CEW89_05910  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CEW89_08800  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CEW89_16615  gcvH; glycine cleavage system protein H [KO:K02437]
CEW89_07165  glycerate kinase [KO:K11529] [EC:2.7.1.165]
CEW89_01445  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
CEW89_17225  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
CEW89_17215  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
CEW89_17210  formate dehydrogenase [KO:K00124]
CEW89_17205  formate dehydrogenase subunit gamma [KO:K00127]
CEW89_07870  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
CEW89_15760  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
CEW89_17300  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
CEW89_04955  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ceh00010  Glycolysis / Gluconeogenesis
ceh00020  Citrate cycle (TCA cycle)
ceh00030  Pentose phosphate pathway
ceh00053  Ascorbate and aldarate metabolism
ceh00071  Fatty acid degradation
ceh00230  Purine metabolism
ceh00250  Alanine, aspartate and glutamate metabolism
ceh00260  Glycine, serine and threonine metabolism
ceh00620  Pyruvate metabolism
ceh00710  Carbon fixation by Calvin cycle
ceh00750  Vitamin B6 metabolism
ceh00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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