KEGG   PATHWAY: dct00053
Entry
dct00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Dendrobium catenatum
Class
Metabolism; Carbohydrate metabolism
Pathway map
dct00053  Ascorbate and aldarate metabolism
dct00053

Module
dct_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:dct00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Dendrobium catenatum [GN:dct]
Gene
110114093  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
110097781  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
110114106  UDP-sugar pyrophosphorylase [KO:K12447] [EC:2.7.7.64]
110109625  glucuronokinase 1 [KO:K16190] [EC:2.7.1.43]
110092758  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
110114175  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
110114164  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
110114165  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
110115211  NADPH-dependent aldo-keto reductase, chloroplastic [KO:K00002] [EC:1.1.1.2]
110093981  aldo-keto reductase family 4 member C10-like isoform X2 [KO:K00002] [EC:1.1.1.2]
114579930  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
110113778  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
110098544  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
110110035  GDP-mannose 3,5-epimerase 1 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
110100274  GDP-L-galactose phosphorylase 2 [KO:K14190] [EC:2.7.7.69]
110110074  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
110116602  GDP-L-galactose phosphorylase 1 isoform X1 [KO:K14190] [EC:2.7.7.69]
110108213  inositol monophosphatase 3 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
110107577  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
110113925  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
110114488  L-galactono-1,4-lactone dehydrogenase 2, mitochondrial isoform X1 [KO:K00225] [EC:1.3.2.3]
110114519  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
110099687  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
110111804  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
110095139  UDP-glucuronate 4-epimerase 4-like [KO:K08679] [EC:5.1.3.6]
110108841  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
110092922  monodehydroascorbate reductase 3, cytosolic-like [KO:K08232] [EC:1.6.5.4]
110103032  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
110092726  monodehydroascorbate reductase 3, cytosolic [KO:K08232] [EC:1.6.5.4]
110116718  monodehydroascorbate reductase 4, peroxisomal isoform X1 [KO:K08232] [EC:1.6.5.4]
110094846  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
110097560  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
110107707  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
110101121  L-ascorbate peroxidase, cytosolic isoform X1 [KO:K00434] [EC:1.11.1.11]
110102819  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
110105563  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
110094742  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
110109026  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
110109027  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
110113582  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
110102783  L-ascorbate oxidase-like isoform X1 [KO:K00423] [EC:1.10.3.3]
110108951  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
110108968  aldehyde dehydrogenase family 3 member F1 isoform X1 [KO:K00128] [EC:1.2.1.3]
110093212  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
110114830  aldehyde dehydrogenase family 2 member B7, mitochondrial [KO:K00128] [EC:1.2.1.3]
110095358  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
110104263  aldehyde dehydrogenase family 3 member H1 isoform X1 [KO:K00128] [EC:1.2.1.3]
110096635  aldehyde dehydrogenase family 7 member B4 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
dct00020  Citrate cycle (TCA cycle)
dct00040  Pentose and glucuronate interconversions
dct00051  Fructose and mannose metabolism
dct00520  Amino sugar and nucleotide sugar metabolism
dct00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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