KEGG   PATHWAY: eci00630
Entry
eci00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli O18:K1:H7 UTI89 (UPEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
eci00630  Glyoxylate and dicarboxylate metabolism
eci00630

Module
eci_M00012  Glyoxylate cycle [PATH:eci00630]
eci_M00621  Glycine cleavage system [PATH:eci00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli O18:K1:H7 UTI89 (UPEC) [GN:eci]
Gene
UTI89_C4574  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
UTI89_C4659  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
UTI89_C3392  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
UTI89_C4573  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
UTI89_C3667  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
UTI89_C0715  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
UTI89_C0364  prpC; putative citrate synthase [KO:K01659] [EC:2.3.3.5]
UTI89_C1547  acnA; aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
UTI89_C0131  acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
UTI89_C2506  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
UTI89_C3247  yqeF; probable acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
UTI89_C3303  putative conserved protein [KO:K01847] [EC:5.4.99.2]
UTI89_C3394  glcD; glycolate oxidase subunit D [KO:K00104] [EC:1.1.99.14]
UTI89_C1925  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
UTI89_C1154  ycdW; putative dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
UTI89_C4093  yiaE; putative dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
UTI89_C3883  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
UTI89_C4459  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
UTI89_C2870  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
UTI89_C3288  gcvP; decarboxylating glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
UTI89_C3290  gcvT; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
UTI89_C4633  subunit of 2-oxoglutarate dehydrogenase [KO:K00382] [EC:1.8.1.4]
UTI89_C0129  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
UTI89_C3289  gcvH; Glycine cleavage system H protein [KO:K02437]
UTI89_C0536  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
UTI89_C5032  gclA; putative glycoxylate carboligase GclA [KO:K01608] [EC:4.1.1.47]
UTI89_C0537  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
UTI89_C5031  gclR; putative regulatory protein GclR [KO:K01816] [EC:5.3.1.22]
UTI89_C5030  ghbD; putative 3-hydroxyisobutyrate dehydrogenase GhbD [KO:K00042] [EC:1.1.1.60]
UTI89_C0538  ybbQ; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
UTI89_C3556  yhaE; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
UTI89_C0542  ybbZ; glycerate kinase 1 [KO:K00865] [EC:2.7.1.165]
UTI89_C3555  yhaD; glycerate kinase 2 [KO:K00865] [EC:2.7.1.165]
UTI89_C5029  gclK; putative glycerate kinase GclK [KO:K00865] [EC:2.7.1.165]
UTI89_C1637  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
UTI89_C3170  fucO; lactaldehyde reductase [KO:K00048] [EC:1.1.1.77]
UTI89_C3497  ttdA; L(+)-tartrate dehydratase alpha subunit [KO:K03779] [EC:4.2.1.32]
UTI89_C3498  ttdB; L-tartrate dehydratase subunit B [KO:K03780] [EC:4.2.1.32]
UTI89_C2053  eda; 2-keto-3-deoxygluconate 6-phosphate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
UTI89_C4480  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
UTI89_C4479  fdoI; formate dehydrogenase-O, cytochrome B556 (FDO) subunit [KO:K00127]
UTI89_C1428  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
UTI89_C2705  putative enzyme [KO:K01577] [EC:4.1.1.8]
UTI89_C2706  yfdW; formyl-coenzyme A transferase monomer [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
eci00010  Glycolysis / Gluconeogenesis
eci00020  Citrate cycle (TCA cycle)
eci00030  Pentose phosphate pathway
eci00053  Ascorbate and aldarate metabolism
eci00071  Fatty acid degradation
eci00230  Purine metabolism
eci00250  Alanine, aspartate and glutamate metabolism
eci00260  Glycine, serine and threonine metabolism
eci00620  Pyruvate metabolism
eci00710  Carbon fixation by Calvin cycle
eci00750  Vitamin B6 metabolism
eci00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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