KEGG   PATHWAY: eih00240
Entry
eih00240                    Pathway                                
Name
Pyrimidine metabolism - Escherichia coli O18:K1:H7 IHE3034 (ExPEC)
Class
Metabolism; Nucleotide metabolism
Pathway map
eih00240  Pyrimidine metabolism
eih00240

Module
eih_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:eih00240]
eih_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:eih00240]
eih_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:eih00240]
eih_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:eih00240]
eih_M00939  Pyrimidine degradation, uracil => 3-hydroxypropanoate [PATH:eih00240]
Other DBs
GO: 0006220 0006213
Organism
Escherichia coli O18:K1:H7 IHE3034 (ExPEC) [GN:eih]
Gene
ECOK1_0026  rihC; nonspecific ribonucleoside hydrolase RihC [KO:K12700] [EC:3.2.2.-]
ECOK1_0030  carA; carbamoyl-phosphate synthase, small subunit [KO:K01956] [EC:6.3.5.5]
ECOK1_0031  carB; carbamoyl-phosphate synthase, large subunit [KO:K01955] [EC:6.3.5.5]
ECOK1_0172  pyrH; UMP kinase [KO:K09903] [EC:2.7.4.22]
ECOK1_0333  codA; cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
ECOK1_0370  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ECOK1_0462  ushA; UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ECOK1_0518  [KO:K06952] [EC:3.1.3.89]
ECOK1_0654  [KO:K01250] [EC:3.2.2.-]
ECOK1_0675  nagD; nagD protein [KO:K02566] [EC:3.1.3.5]
ECOK1_0977  cmk; cytidylate kinase [KO:K00945] [EC:2.7.4.25]
ECOK1_1005  pyrD; dihydroorotate oxidase [KO:K00254] [EC:1.3.5.2]
ECOK1_1059  [KO:K09024] [EC:1.5.1.-]
ECOK1_1060  [KO:K09019] [EC:1.1.1.-]
ECOK1_1061  [KO:K09023] [EC:3.5.1.-]
ECOK1_1062  [KO:K09021]
ECOK1_1063  [KO:K09020] [EC:3.5.1.110]
ECOK1_1064  [KO:K09018] [EC:1.14.99.46]
ECOK1_1170  pyrC; dihydroorotase, homodimeric type [KO:K01465] [EC:3.5.2.3]
ECOK1_1205  tmk; thymidylate kinase [KO:K00943] [EC:2.7.4.9]
ECOK1_1393  tdk; thymidine kinase [KO:K00857] [EC:2.7.1.21]
ECOK1_1497  pyrF; orotidine 5'-phosphate decarboxylase [KO:K01591] [EC:4.1.1.23]
ECOK1_1692  [KO:K16066] [EC:1.1.1.381 1.1.1.-]
ECOK1_1880  nudG; CTP pyrophosphohydrolase [KO:K08320] [EC:3.6.1.65]
ECOK1_2295  dcd; deoxycytidine triphosphate deaminase [KO:K01494] [EC:3.5.4.13]
ECOK1_2296  udk; uridine kinase [KO:K00876] [EC:2.7.1.48]
ECOK1_2373  cdd; cytidine deaminase [KO:K01489] [EC:3.5.4.5]
ECOK1_2376  [KO:K17722] [EC:1.3.1.1]
ECOK1_2377  [KO:K17723] [EC:1.3.1.1]
ECOK1_2394  [KO:K10213] [EC:3.2.2.8]
ECOK1_2397  [KO:K16329] [EC:4.2.1.70]
ECOK1_2398  [KO:K16328] [EC:2.7.1.83]
ECOK1_2469  nrdA; ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
ECOK1_2470  nrdB; ribonucleoside-diphosphate reductase, beta subunit [KO:K00526] [EC:1.17.4.1]
ECOK1_2524  yfbR; 5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
ECOK1_2794  upp; uracil phosphoribosyltransferase [KO:K00761] [EC:2.4.2.9]
ECOK1_2866  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ECOK1_3018  [KO:K06952] [EC:3.1.3.89]
ECOK1_3043  nrdE; ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
ECOK1_3044  nrdF; ribonucleoside-diphosphate reductase, beta subunit [KO:K00526] [EC:1.17.4.1]
ECOK1_3123  surE; multifunctional protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ECOK1_3154  pyrG; CTP synthase [KO:K01937] [EC:6.3.4.2]
ECOK1_3155  [KO:K04765] [EC:3.6.1.9]
ECOK1_3171  [KO:K06966] [EC:3.2.2.10 3.2.2.-]
ECOK1_3231  thyA; thymidylate synthase [KO:K00560] [EC:2.1.1.45]
ECOK1_3259  hydA; dihydropyrimidinase [KO:K01464] [EC:3.5.2.2]
ECOK1_3515  [KO:K07043] [EC:3.6.1.-]
ECOK1_3660  maf; septum formation protein Maf [KO:K06287] [EC:3.6.1.-]
ECOK1_4081  dut; dUTP diphosphatase [KO:K01520] [EC:3.6.1.23]
ECOK1_4083  pyrE; orotate phosphoribosyltransferase [KO:K00762] [EC:2.4.2.10]
ECOK1_4296  udp; uridine phosphorylase [KO:K00757] [EC:2.4.2.3]
ECOK1_4733  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ECOK1_4754  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
ECOK1_4761  pyrI; aspartate carbamoyltransferase, regulatory subunit [KO:K00610]
ECOK1_4762  pyrB; aspartate carbamoyltransferase, catalytic subunit [KO:K00609] [EC:2.1.3.2]
ECOK1_4885  yjjG; 5-nucleotidase YjjG [KO:K08723] [EC:3.1.3.-]
ECOK1_4890  [KO:K06952] [EC:3.1.3.89]
ECOK1_4948  deoA; thymidine phosphorylase [KO:K00758] [EC:2.4.2.4]
Compound
C00015  UDP
C00039  DNA
C00046  RNA
C00055  CMP
C00063  CTP
C00064  L-Glutamine
C00075  UTP
C00086  Urea
C00099  beta-Alanine
C00105  UMP
C00106  Uracil
C00112  CDP
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00169  Carbamoyl phosphate
C00178  Thymine
C00214  Thymidine
C00222  3-Oxopropanoate
C00239  dCMP
C00295  Orotate
C00299  Uridine
C00337  (S)-Dihydroorotate
C00363  dTDP
C00364  dTMP
C00365  dUMP
C00380  Cytosine
C00383  Malonate
C00429  5,6-Dihydrouracil
C00438  N-Carbamoyl-L-aspartate
C00458  dCTP
C00459  dTTP
C00460  dUTP
C00475  Cytidine
C00526  Deoxyuridine
C00672  2-Deoxy-D-ribose 1-phosphate
C00705  dCDP
C00813  Barbiturate
C00881  Deoxycytidine
C00941  3',5'-Cyclic CMP
C01013  3-Hydroxypropanoate
C01103  Orotidine 5'-phosphate
C01168  Pseudouridine 5'-phosphate
C01205  (R)-3-Amino-2-methylpropanoate
C01346  dUDP
C01368  3'-UMP
C01563  Carbamate
C02067  Pseudouridine
C02170  Methylmalonate
C02354  2',3'-Cyclic CMP
C02355  2',3'-Cyclic UMP
C02376  5-Methylcytosine
C02642  3-Ureidopropionate
C03997  5-Hydroxymethyldeoxycytidylate
C05281  5-Methylbarbiturate
C05822  3'-CMP
C06198  P1,P4-Bis(5'-uridyl) tetraphosphate
C11038  2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
C11039  2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
C15607  3-Oxo-3-ureidopropanoate
C20231  (Z)-3-Ureidoacrylate peracid
C20249  (Z)-3-Peroxyaminoacrylate
C20253  Aminoacrylate
C20254  Ureidoacrylate
C20846  3-Oxo-3-ureidoisobutyrate
C21028  (R)-5,6-Dihydrothymine
C21029  (R)-3-Ureidoisobutyrate
C22509  3',5'-Cyclic UMP
Related
pathway
eih00030  Pentose phosphate pathway
eih00220  Arginine biosynthesis
eih00250  Alanine, aspartate and glutamate metabolism
eih00280  Valine, leucine and isoleucine degradation
eih00410  beta-Alanine metabolism
KO pathway
ko00240   

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