KEGG   PATHWAY: ell00630
Entry
ell00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli W
Class
Metabolism; Carbohydrate metabolism
Pathway map
ell00630  Glyoxylate and dicarboxylate metabolism
ell00630

Module
ell_M00012  Glyoxylate cycle [PATH:ell00630]
ell_M00621  Glycine cleavage system [PATH:ell00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli W [GN:ell]
Gene
WFL_21265  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
WFL_21565  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
WFL_15835  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
WFL_21260  aceB; malate synthase [KO:K01638] [EC:2.3.3.9]
WFL_17135  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
WFL_03780  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
WFL_02020  prpC; methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
WFL_06675  acnA; aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
WFL_00565  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
WFL_15075  yqeF; putative acyltransferase [KO:K00626] [EC:2.3.1.9]
WFL_15485  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
WFL_15855  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
WFL_15850  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
WFL_15845  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
WFL_09320  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
WFL_05565  ghrA; bifunctional glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
WFL_18680  ghrB; bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
WFL_17780  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
WFL_20335  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
WFL_13600  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
WFL_15420  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
WFL_15430  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
WFL_00555  lpd; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
WFL_15425  gcvH; glycine cleavage system protein H [KO:K02437]
WFL_02870  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
WFL_02875  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
WFL_02880  glxR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
WFL_16600  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
WFL_16595  garK; glycerate kinase I [KO:K00865] [EC:2.7.1.165]
WFL_02900  glxK; glycerate kinase II [KO:K00865] [EC:2.7.1.165]
WFL_07545  aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
WFL_14700  fucO; L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
WFL_16260  ttdA; tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
WFL_16265  ttdB; L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
WFL_09675  dmlA; tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
WFL_09930  eda; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
WFL_20475  fdoG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
WFL_20480  formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
WFL_20470  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
WFL_20465  fdoI; formate dehydrogenase-O subunit gamma [KO:K00127]
WFL_06460  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
WFL_12785  oxc; putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
WFL_12790  frc; formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ell00010  Glycolysis / Gluconeogenesis
ell00020  Citrate cycle (TCA cycle)
ell00030  Pentose phosphate pathway
ell00053  Ascorbate and aldarate metabolism
ell00071  Fatty acid degradation
ell00230  Purine metabolism
ell00250  Alanine, aspartate and glutamate metabolism
ell00260  Glycine, serine and threonine metabolism
ell00620  Pyruvate metabolism
ell00710  Carbon fixation by Calvin cycle
ell00750  Vitamin B6 metabolism
ell00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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