KEGG   PATHWAY: ggr00230
Entry
ggr00230                    Pathway                                
Name
Purine metabolism - Gemmatimonas groenlandica
Class
Metabolism; Nucleotide metabolism
Pathway map
ggr00230  Purine metabolism
ggr00230

Module
ggr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ggr00230]
ggr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ggr00230]
ggr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ggr00230]
ggr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ggr00230]
ggr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ggr00230]
ggr_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ggr00230]
Other DBs
GO: 0006163 0042278
Organism
Gemmatimonas groenlandica [GN:ggr]
Gene
HKW67_15845  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HKW67_07105  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
HKW67_20955  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
HKW67_05805  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
HKW67_08310  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
HKW67_05325  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
HKW67_02320  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
HKW67_07985  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
HKW67_05330  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
HKW67_05340  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
HKW67_05335  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
HKW67_06950  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
HKW67_03130  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
HKW67_03135  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
HKW67_05355  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HKW67_05360  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HKW67_07990  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
HKW67_06000  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
HKW67_22170  hypothetical protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
HKW67_06020  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HKW67_02620  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
HKW67_07330  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
HKW67_06325  laccase domain-containing protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
HKW67_07360  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
HKW67_02215  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
HKW67_05830  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HKW67_22145  yjjX; inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
HKW67_06220  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
HKW67_13790  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
HKW67_13785  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
HKW67_13780  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
HKW67_05285  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
HKW67_05600  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
HKW67_10150  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
HKW67_09940  R2-like ligand-binding oxidase [KO:K00526] [EC:1.17.4.1]
HKW67_04565  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
HKW67_02535  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HKW67_02390  FHA domain-containing protein [KO:K01768] [EC:4.6.1.1]
HKW67_10360  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
HKW67_02615  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
HKW67_02605  hypothetical protein [KO:K08693] [EC:3.1.4.16 3.1.3.6 3.1.3.5]
HKW67_10410  adenylate kinase [KO:K00939] [EC:2.7.4.3]
HKW67_07115  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
HKW67_09655  hypothetical protein [KO:K07127] [EC:3.5.2.17]
HKW67_09665  hypothetical protein [KO:K07127] [EC:3.5.2.17]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ggr00030  Pentose phosphate pathway
ggr00220  Arginine biosynthesis
ggr00250  Alanine, aspartate and glutamate metabolism
ggr00260  Glycine, serine and threonine metabolism
ggr00340  Histidine metabolism
ggr00630  Glyoxylate and dicarboxylate metabolism
ggr00730  Thiamine metabolism
ggr00740  Riboflavin metabolism
ggr00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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