KEGG   PATHWAY: ham00230
Entry
ham00230                    Pathway                                
Name
Purine metabolism - Halomonas sp. R57-5
Class
Metabolism; Nucleotide metabolism
Pathway map
ham00230  Purine metabolism
ham00230

Module
ham_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ham00230]
ham_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ham00230]
ham_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ham00230]
ham_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ham00230]
ham_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ham00230]
ham_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ham00230]
ham_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:ham00230]
Other DBs
GO: 0006163 0042278
Organism
Halomonas sp. R57-5 [GN:ham]
Gene
HALO3060  Nucleoside diphosphate pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HALO3262  ADP-ribose diphosphatase [KO:K08312] [EC:3.6.1.-]
HALO3575  Phosphopentomutase-Phosphodeoxyribomutase [KO:K01839] [EC:5.4.2.7]
HALO3182  Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
HALO3188  Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
HALO4085  Phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
HALO1531  Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
HALO2208  Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
HALO1734  Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
HALO2222  Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
HALO1057  Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
HALO2223  Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
HALO1672  Phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
HALO1671  Phosphoribosylaminoimidazole carboxylase, core [KO:K01588] [EC:5.4.99.18]
HALO1072  Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HALO3350  Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HALO2634  Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
HALO2235  Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
HALO1267  5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HALO3261  Putative hydrolase [KO:K20881] [EC:3.1.3.-]
HALO3576  Purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
HALO0958  Multi-copper polyphenol oxidoreductase, laccase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
HALO2250  Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
HALO3797  Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
HALO3937  Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HALO4535  Non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
HALO2236  Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
HALO2283  Xanthine dehydrogenase [KO:K13481] [EC:1.17.1.4]
HALO2282  Xanthine dehydrogenase/oxidase [KO:K13482] [EC:1.17.1.4]
HALO0182  Molybdopterin binding aldehyde oxidase and xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
HALO0181  Putative oxidoreductase [KO:K11178] [EC:1.17.1.4]
HALO0180  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
HALO3590  GMP synthase subunit A [KO:K01951] [EC:6.3.5.2]
HALO3796  GMP synthase [KO:K01951] [EC:6.3.5.2]
HALO2280  Guanine deaminase [KO:K01487] [EC:3.5.4.3]
HALO0024  Guanylate kinase-GMP kinase [KO:K00942] [EC:2.7.4.8]
HALO2873  Ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
HALO4428  Ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
HALO2872  Ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HALO4174  Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
HALO0026  Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
HALO4047  Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HALO2844  GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
HALO2993  Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
HALO2556  LOG family protein ygdH [KO:K06966] [EC:3.2.2.10 3.2.2.-]
HALO2279  Adenine deaminase [KO:K21053] [EC:3.5.4.2]
HALO1079  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
HALO2843  Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
HALO3058  3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
HALO2092  3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
HALO1286  Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
HALO3056  Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
HALO3057  Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
HALO1127  5-hydroxyisourate hydrolase 2 [KO:K07127] [EC:3.5.2.17]
HALO1126  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
HALO1145  Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
HALO1146  Chitin deacetylase 1 [KO:K16842] [EC:3.5.2.5]
HALO0661  Amidase, hydantoinase/carbamoylase family [KO:K02083] [EC:3.5.3.9]
HALO1153  Putative uncharacterized protein [KO:K14977] [EC:3.5.3.26]
HALO1154  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
HALO0291  Urease subunit alpha-Urea amidohydrolase subunit alpha [KO:K01428] [EC:3.5.1.5]
HALO0290  Urease subunit beta-Urea amidohydrolase subunit beta [KO:K01429] [EC:3.5.1.5]
HALO0289  Urease subunit gamma [KO:K01430] [EC:3.5.1.5]
HALO3322  Gamma-glutamyltranspeptidase [KO:K22602] [EC:3.5.1.126]
HALO3768  Gamma-glutamyltranspeptidase [KO:K22602] [EC:3.5.1.126]
HALO2709  Carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ham00030  Pentose phosphate pathway
ham00220  Arginine biosynthesis
ham00250  Alanine, aspartate and glutamate metabolism
ham00260  Glycine, serine and threonine metabolism
ham00340  Histidine metabolism
ham00630  Glyoxylate and dicarboxylate metabolism
ham00730  Thiamine metabolism
ham00740  Riboflavin metabolism
ham00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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