KEGG   PATHWAY: hrj00830
Entry
hrj00830                    Pathway                                
Name
Retinol metabolism - Haliotis rubra (blacklip abalone)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
hrj00830  Retinol metabolism
hrj00830

Other DBs
GO: 0006776
Organism
Haliotis rubra (blacklip abalone) [GN:hrj]
Gene
124284641  beta,beta-carotene 15,15'-dioxygenase-like [KO:K00515] [EC:1.13.11.63]
124284642  beta,beta-carotene 15,15'-dioxygenase-like [KO:K00515] [EC:1.13.11.63]
124284668  beta,beta-carotene 15,15'-dioxygenase-like [KO:K00515] [EC:1.13.11.63]
124274827  beta,beta-carotene 15,15'-dioxygenase-like [KO:K00515] [EC:1.13.11.63]
124291761  alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
124254246  dehydrogenase/reductase SDR family member 4-like isoform X1 [KO:K11147] [EC:1.1.-.-]
124290118  retinol dehydrogenase 11-like [KO:K11153] [EC:1.1.1.300]
124267212  LOW QUALITY PROTEIN: retinol dehydrogenase 12-like [KO:K11153] [EC:1.1.1.300]
124290430  LOW QUALITY PROTEIN: retinol dehydrogenase 12-like [KO:K11153] [EC:1.1.1.300]
124285180  retinol dehydrogenase 13-like [KO:K11153] [EC:1.1.1.300]
124267075  retinol dehydrogenase 14-like [KO:K11153] [EC:1.1.1.300]
124278162  retinol dehydrogenase 7-like isoform X1 [KO:K11154] [EC:1.1.1.-]
124278167  retinol dehydrogenase 7-like [KO:K11154] [EC:1.1.1.-]
124278168  retinol dehydrogenase 7-like [KO:K11154] [EC:1.1.1.-]
124281125  dehydrogenase/reductase SDR family member 9-like isoform X1 [KO:K11154] [EC:1.1.1.-]
124289002  short-chain dehydrogenase/reductase family 16C member 6-like [KO:K15734] [EC:1.1.1.105]
124280962  short-chain dehydrogenase/reductase 3-like [KO:K15734] [EC:1.1.1.105]
124269994  epidermal retinol dehydrogenase 2-like [KO:K15734] [EC:1.1.1.105]
124269995  epidermal retinol dehydrogenase 2-like [KO:K15734] [EC:1.1.1.105]
124278165  retinol dehydrogenase 7-like [KO:K13369] [EC:1.1.1.62 1.1.1.105 1.1.1.239]
124262929  diacylglycerol O-acyltransferase 1-like isoform X1 [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
124262196  patatin-like phospholipase domain-containing protein 4 [KO:K11157] [EC:3.1.1.-]
124288920  LOW QUALITY PROTEIN: retinal dehydrogenase 2-like [KO:K07249] [EC:1.2.1.36]
124289007  retinal dehydrogenase 2-like isoform X1 [KO:K07249] [EC:1.2.1.36]
124288919  LOW QUALITY PROTEIN: aldehyde dehydrogenase, mitochondrial-like [KO:K07249] [EC:1.2.1.36]
124267589  cytochrome P450 26B1-like [KO:K07437] [EC:1.14.14.-]
124261138  cytochrome P450 26A1-like [KO:K07437] [EC:1.14.14.-]
124274374  cytochrome P450 26B1-like [KO:K07437] [EC:1.14.14.-]
124274375  cytochrome P450 26B1-like [KO:K07437] [EC:1.14.14.-]
124274379  cytochrome P450 26B1-like [KO:K07437] [EC:1.14.14.-]
124274380  cytochrome P450 26B1-like [KO:K07437] [EC:1.14.14.-]
124281921  cytochrome P450 26B1-like [KO:K12664] [EC:1.14.14.-]
124276990  cytochrome P450 1A1-like [KO:K07408] [EC:1.14.14.1]
124268175  cytochrome P450 1A1-like [KO:K07408] [EC:1.14.14.1]
124282406  cytochrome P450 1A1-like [KO:K07408] [EC:1.14.14.1]
124291019  cytochrome P450 2C23-like [KO:K07413] [EC:1.14.14.1]
124281202  cytochrome P450 2C23-like [KO:K07413] [EC:1.14.14.1]
124262364  cytochrome P450 18a1-like [KO:K07413] [EC:1.14.14.1]
124286777  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124286779  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124286783  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124286795  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124286802  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124286806  cytochrome P450 3A13-like [KO:K07424] [EC:1.14.14.1]
124286809  cytochrome P450 3A4-like [KO:K07424] [EC:1.14.14.1]
124263719  cytochrome P450 3A5-like isoform X1 [KO:K07424] [EC:1.14.14.1]
124264464  cytochrome P450 3A13-like [KO:K07424] [EC:1.14.14.1]
124264465  cytochrome P450 3A13-like [KO:K07424] [EC:1.14.14.1]
124264466  cytochrome P450 3A8-like [KO:K07424] [EC:1.14.14.1]
124264470  cytochrome P450 3A13-like [KO:K07424] [EC:1.14.14.1]
124264471  cytochrome P450 3A4-like [KO:K07424] [EC:1.14.14.1]
124265082  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124253624  cytochrome P450 3A41-like [KO:K07424] [EC:1.14.14.1]
124253866  cytochrome P450 3A12-like [KO:K07424] [EC:1.14.14.1]
124265814  cytochrome P450 3A11-like [KO:K07424] [EC:1.14.14.1]
124278061  cytochrome P450 3A6-like [KO:K07424] [EC:1.14.14.1]
124278062  cytochrome P450 3A41-like [KO:K07424] [EC:1.14.14.1]
124278084  cytochrome P450 3A11-like [KO:K07424] [EC:1.14.14.1]
124278086  cytochrome P450 3A8-like [KO:K07424] [EC:1.14.14.1]
124278495  LOW QUALITY PROTEIN: cytochrome P450 3A19-like [KO:K07424] [EC:1.14.14.1]
124279834  cytochrome P450 3A24-like [KO:K07424] [EC:1.14.14.1]
124280060  cytochrome P450 3A11-like [KO:K07424] [EC:1.14.14.1]
124255864  cytochrome P450 3A28-like [KO:K07424] [EC:1.14.14.1]
124255889  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124291272  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124256900  cytochrome P450 3A41-like [KO:K07424] [EC:1.14.14.1]
124280961  cytochrome P450 3A19-like [KO:K07424] [EC:1.14.14.1]
124269548  cytochrome P450 3A41-like [KO:K07424] [EC:1.14.14.1]
124282708  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124282768  cytochrome P450 3A5-like [KO:K07424] [EC:1.14.14.1]
124282769  cytochrome P450 3A24-like [KO:K07424] [EC:1.14.14.1]
124282777  cytochrome P450 3A29-like isoform X1 [KO:K07424] [EC:1.14.14.1]
124282778  cytochrome P450 3A5-like [KO:K07424] [EC:1.14.14.1]
124282779  cytochrome P450 3A5-like [KO:K07424] [EC:1.14.14.1]
124282887  cytochrome P450 3A8-like [KO:K07424] [EC:1.14.14.1]
124271109  cytochrome P450 3A24-like [KO:K07424] [EC:1.14.14.1]
124271110  cytochrome P450 3A24-like [KO:K07424] [EC:1.14.14.1]
124282890  cytochrome P450 3A6-like [KO:K07424] [EC:1.14.14.1]
124272227  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124272229  cytochrome P450 3A29-like [KO:K07424] [EC:1.14.14.1]
124283644  cytochrome P450 3A8-like [KO:K07424] [EC:1.14.14.1]
124283767  cytochrome P450 3A19-like isoform X1 [KO:K07424] [EC:1.14.14.1]
124284397  cytochrome P450 3A8-like [KO:K07424] [EC:1.14.14.1]
124274142  cytochrome P450 3A21-like [KO:K07424] [EC:1.14.14.1]
124254159  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
124254160  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
124254161  UDP-glucuronosyltransferase 1-2-like [KO:K00699] [EC:2.4.1.17]
124254162  LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2A2-like [KO:K00699] [EC:2.4.1.17]
124254167  UDP-glucuronosyltransferase 2B7-like [KO:K00699] [EC:2.4.1.17]
124254171  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
124254182  UDP-glucuronosyltransferase 1A1-like [KO:K00699] [EC:2.4.1.17]
124254190  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
124266450  UDP-glucuronosyltransferase 2B31-like [KO:K00699] [EC:2.4.1.17]
124266844  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
124292152  2-hydroxyacylsphingosine 1-beta-galactosyltransferase-like [KO:K00699] [EC:2.4.1.17]
124272475  UDP-glucuronosyltransferase 2B17-like [KO:K00699] [EC:2.4.1.17]
124272887  UDP-glucuronosyltransferase 1-2-like [KO:K00699] [EC:2.4.1.17]
124254166  all-trans-retinol 13,14-reductase-like [KO:K09516] [EC:1.3.99.23]
124292172  cytochrome P450 27C1-like [KO:K17951] [EC:1.14.19.53]
Compound
C00376  Retinal
C00473  Retinol
C00777  Retinoate
C00778  Rhodopsin
C00899  11-cis-Retinol
C02075  Retinyl ester
C02094  beta-Carotene
C02110  11-cis-Retinal
C02588  Retinyl palmitate
C03455  11-cis-Retinyl palmitate
C05914  Bathorhodopsin
C05915  Lumirhodopsin
C05916  Metarhodopsin
C05917  Iodopsin
C11061  all-trans-Retinoyl-beta-glucuronide
C15492  all-trans-13,14-Dihydroretinol
C15493  9-cis-Retinoic acid
C16677  all-trans-4-Hydroxyretinoic acid
C16678  all-trans-4-Oxoretinoic acid
C16679  all-trans-18-Hydroxyretinoic acid
C16680  all-trans-5,6-Epoxyretinoic acid
C16681  9-cis-Retinal
C16682  9-cis-Retinol
C16683  4-Oxoretinol
C21797  all-trans-3,4-Didehydroretinol
Reference
PMID:16968212
  Authors
Travis GH, Golczak M, Moise AR, Palczewski K.
  Title
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
  Journal
Annu Rev Pharmacol Toxicol 47:469-512 (2007)
DOI:10.1146/annurev.pharmtox.47.120505.105225
Reference
PMID:17618621
  Authors
Muniz A, Villazana-Espinoza ET, Hatch AL, Trevino SG, Allen DM, Tsin AT.
  Title
A novel cone visual cycle in the cone-dominated retina.
  Journal
Exp Eye Res 85:175-84 (2007)
DOI:10.1016/j.exer.2007.05.003
Reference
PMID:11093772
  Authors
Marill J, Cresteil T, Lanotte M, Chabot GG.
  Title
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
  Journal
Mol Pharmacol 58:1341-8 (2000)
DOI:10.1124/mol.58.6.1341
Reference
PMID:17893666
  Authors
Nezzar H, Chiambaretta F, Marceau G, Blanchon L, Faye B, Dechelotte P, Rigal D, Sapin V.
  Title
Molecular and metabolic retinoid pathways in the human ocular surface.
  Journal
Mol Vis 13:1641-50 (2007)
Reference
PMID:16688755
  Authors
Blomhoff R, Blomhoff HK.
  Title
Overview of retinoid metabolism and function.
  Journal
J Neurobiol 66:606-30 (2006)
DOI:10.1002/neu.20242
Reference
PMID:16428379
  Authors
Liden M, Eriksson U.
  Title
Understanding retinol metabolism: structure and function of retinol dehydrogenases.
  Journal
J Biol Chem 281:13001-4 (2006)
DOI:10.1074/jbc.R500027200
KO pathway
ko00830   
LinkDB

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