KEGG   PATHWAY: kom00330
Entry
kom00330                    Pathway                                
Name
Arginine and proline metabolism - Klebsiella michiganensis M1
Class
Metabolism; Amino acid metabolism
Pathway map
kom00330  Arginine and proline metabolism
kom00330

Module
kom_M00015  Proline biosynthesis, glutamate => proline [PATH:kom00330]
kom_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:kom00330]
kom_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:kom00330]
kom_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:kom00330]
kom_M00970  Proline degradation, proline => glutamate [PATH:kom00330]
Other DBs
GO: 0006525 0006560
Organism
Klebsiella michiganensis M1 [GN:kom]
Gene
HR38_19145  creatinine amidohydrolase [KO:K01470] [EC:3.5.2.10]
HR38_03125  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
HR38_27865  creatininase [KO:K08688] [EC:3.5.3.3]
HR38_01005  arginine decarboxylase [KO:K01585] [EC:4.1.1.19]
HR38_01000  agmatinase [KO:K01480] [EC:3.5.3.11]
HR38_01140  ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
HR38_09840  spermidine synthase [KO:K00797] [EC:2.5.1.16]
HR38_09835  S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
HR38_01800  putrescine--2-oxoglutarate aminotransferase [KO:K09251] [EC:2.6.1.82]
HR38_18080  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
HR38_19835  spermidine acetyltransferase [KO:K00657] [EC:2.3.1.57]
HR38_26315  agmatinase [KO:K12255] [EC:3.5.3.7]
HR38_12465  amidase [KO:K01426] [EC:3.5.1.4]
HR38_08570  acetamidase [KO:K01426] [EC:3.5.1.4]
HR38_18830  amidase [KO:K01426] [EC:3.5.1.4]
HR38_16435  arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
HR38_16430  acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
HR38_16440  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
HR38_16450  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
HR38_15455  gamma-glutamylputrescine synthetase [KO:K09470] [EC:6.3.1.11]
HR38_15435  gamma-glutamylputrescine oxidoreductase [KO:K09471] [EC:1.4.3.-]
HR38_15440  aldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
HR38_15450  gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
HR38_00690  arginase [KO:K01476] [EC:3.5.3.1]
HR38_11150  pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
HR38_19375  pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
HR38_15540  putA; transcriptional regulator [KO:K13821] [EC:1.5.5.2 1.2.1.88]
HR38_10820  gamma-glutamyl kinase [KO:K00931] [EC:2.7.2.11]
HR38_10815  gamma-glutamyl phosphate reductase [KO:K00147] [EC:1.2.1.41]
HR38_23395  proline iminopeptidase [KO:K01259] [EC:3.4.11.5]
HR38_16985  aspartate aminotransferase [KO:K00812] [EC:2.6.1.1]
HR38_14885  aspartate aminotransferase [KO:K00812] [EC:2.6.1.1]
HR38_14620  aromatic amino acid aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
kom00020  Citrate cycle (TCA cycle)
kom00220  Arginine biosynthesis
kom00250  Alanine, aspartate and glutamate metabolism
kom00260  Glycine, serine and threonine metabolism
kom00270  Cysteine and methionine metabolism
kom00310  Lysine degradation
kom00410  beta-Alanine metabolism
kom00470  D-Amino acid metabolism
kom00480  Glutathione metabolism
kom00630  Glyoxylate and dicarboxylate metabolism
kom00650  Butanoate metabolism
kom00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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