KEGG   PATHWAY: kpas02024
Entry
kpas02024                   Pathway                                
Name
Quorum sensing - Klebsiella pasteurii
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
kpas02024  Quorum sensing
kpas02024

Other DBs
GO: 0009372
Organism
Klebsiella pasteurii [GN:kpas]
Gene
LUW96_00585  luxS; S-ribosylhomocysteine lyase [KO:K07173] [EC:4.4.1.21]
LUW96_09020  hfq; RNA chaperone Hfq [KO:K03666]
LUW96_18700  anthranilate synthase component 1 [KO:K01657] [EC:4.1.3.27]
LUW96_25725  glycosyltransferase family 2 protein [KO:K12990] [EC:2.4.1.-]
LUW96_15550  aroG; 3-deoxy-7-phosphoheptulonate synthase AroG [KO:K01626] [EC:2.5.1.54]
LUW96_21795  3-deoxy-7-phosphoheptulonate synthase [KO:K01626] [EC:2.5.1.54]
LUW96_23495  aroH; 3-deoxy-7-phosphoheptulonate synthase AroH [KO:K01626] [EC:2.5.1.54]
LUW96_00070  aroF; 3-deoxy-7-phosphoheptulonate synthase AroF [KO:K01626] [EC:2.5.1.54]
LUW96_21805  isochorismatase family protein [KO:K20261] [EC:3.3.2.15]
LUW96_21810  anthranilate synthase family protein [KO:K13063] [EC:2.6.1.86]
LUW96_02890  qseC; two-component system sensor histidine kinase QseC [KO:K07645] [EC:2.7.13.3]
LUW96_02885  qseB; two-component system response regulator QseB [KO:K07666]
LUW96_28145  HAMP domain-containing histidine kinase [KO:K07711] [EC:2.7.13.3]
LUW96_28135  glrR; two-component system response regulator GlrR [KO:K07715]
LUW96_15210  kdpE; two-component system response regulator KdpE [KO:K07667]
LUW96_12525  MASE1 domain-containing protein [KO:K20263] [EC:2.7.13.3]
LUW96_12530  response regulator transcription factor [KO:K20264]
LUW96_24745  sdiA; transcriptional regulator SdiA [KO:K07782]
LUW96_25875  LuxR family transcriptional regulator [KO:K07782]
LUW96_03190  lsrB; autoinducer 2 ABC transporter substrate-binding protein LsrB [KO:K10555]
LUW96_03200  lsrC; autoinducer 2 ABC transporter permease LsrC [KO:K10556]
LUW96_03195  autoinducer 2 import system permease LsrD [KO:K10557]
LUW96_03205  lsrA; autoinducer 2 ABC transporter ATP-binding protein LsrA [KO:K10558]
LUW96_03215  lsrK; autoinducer-2 kinase [KO:K11216] [EC:2.7.1.189]
LUW96_03210  lsrR; transcriptional regulator LsrR [KO:K11531]
LUW96_03185  lsrF; 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase [KO:K08321] [EC:2.3.1.245]
LUW96_03180  lsrG; (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase [KO:K11530] [EC:5.3.1.32]
LUW96_20255  ABC transporter substrate-binding protein [KO:K02055]
LUW96_20270  ABC transporter permease [KO:K02053]
LUW96_20265  ABC transporter permease [KO:K02054]
LUW96_20260  ABC transporter ATP-binding protein [KO:K02052]
LUW96_12470  ABC transporter substrate-binding protein [KO:K01999]
LUW96_14120  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
LUW96_26100  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
LUW96_04880  livK; high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK [KO:K01999]
LUW96_04890  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
LUW96_12465  branched-chain amino acid ABC transporter permease [KO:K01997]
LUW96_14140  branched-chain amino acid ABC transporter permease [KO:K01997]
LUW96_26095  branched-chain amino acid ABC transporter permease [KO:K01997]
LUW96_04875  livH; high-affinity branched-chain amino acid ABC transporter permease LivH [KO:K01997]
LUW96_12460  branched-chain amino acid ABC transporter permease [KO:K01998]
LUW96_14135  ABC transporter ATP-binding protein [KO:K01998]
LUW96_04870  livM; branched chain amino acid ABC transporter permease LivM [KO:K01998]
LUW96_12455  ABC transporter ATP-binding protein [KO:K01995]
LUW96_14130  ABC transporter ATP-binding protein [KO:K01995]
LUW96_26085  ATP-binding cassette domain-containing protein [KO:K01995]
LUW96_04865  livG; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG [KO:K01995]
LUW96_12450  ABC transporter ATP-binding protein [KO:K01996]
LUW96_14125  ABC transporter ATP-binding protein [KO:K01996]
LUW96_26080  ABC transporter ATP-binding protein [KO:K01996]
LUW96_04860  livF; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF [KO:K01996]
LUW96_17445  pectate lyase [KO:K01728] [EC:4.2.2.2]
LUW96_24780  rcsA; transcriptional regulator RcsA [KO:K07781]
LUW96_24175  fadD; long-chain-fatty-acid--CoA ligase FadD [KO:K01897] [EC:6.2.1.3]
LUW96_04505  crp; cAMP-activated global transcriptional regulator CRP [KO:K10914]
LUW96_07465  Crp/Fnr family transcriptional regulator [KO:K10914]
LUW96_08425  zur; zinc uptake transcriptional repressor Zur [KO:K09823]
LUW96_18775  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
LUW96_12825  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
LUW96_20330  DMT family transporter [KO:K09936]
LUW96_20770  DMT family transporter [KO:K09936]
LUW96_20775  DMT family transporter [KO:K09936]
LUW96_20030  efflux transporter outer membrane subunit [KO:K18139]
LUW96_06230  efflux transporter outer membrane subunit [KO:K18139]
LUW96_17040  ABC transporter substrate-binding protein [KO:K15580]
LUW96_19350  peptide ABC transporter substrate-binding protein [KO:K15580]
LUW96_23650  oppA; oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580]
LUW96_23645  oppB; oligopeptide ABC transporter permease OppB [KO:K15581]
LUW96_23640  oppC; oligopeptide ABC transporter permease OppC [KO:K15582]
LUW96_23635  ABC transporter ATP-binding protein [KO:K15583]
LUW96_23630  oppF; murein tripeptide/oligopeptide ABC transporter ATP-binding protein OppF [KO:K10823]
LUW96_14420  ABC transporter substrate-binding protein [KO:K02035]
LUW96_20615  TIGR04028 family ABC transporter substrate-binding protein [KO:K02035]
LUW96_21370  ABC transporter substrate-binding protein [KO:K02035]
LUW96_23050  ABC transporter substrate-binding protein [KO:K02035]
LUW96_25845  ABC transporter substrate-binding protein [KO:K02035]
LUW96_25990  ABC transporter substrate-binding protein [KO:K02035]
LUW96_14425  ABC transporter permease [KO:K02033]
LUW96_20610  ABC transporter permease [KO:K02033]
LUW96_21365  ABC transporter permease [KO:K02033]
LUW96_23055  ABC transporter permease [KO:K02033]
LUW96_25865  ABC transporter permease [KO:K02033]
LUW96_25985  ABC transporter permease [KO:K02033]
LUW96_14430  ABC transporter permease [KO:K02034]
LUW96_20605  ABC transporter permease [KO:K02034]
LUW96_21360  ABC transporter permease [KO:K02034]
LUW96_23060  ABC transporter permease [KO:K02034]
LUW96_25860  ABC transporter permease [KO:K02034]
LUW96_25980  ABC transporter permease [KO:K02034]
LUW96_14440  ABC transporter ATP-binding protein [KO:K02031]
LUW96_20600  ABC transporter ATP-binding protein [KO:K02031 K02032]
LUW96_21355  ABC transporter ATP-binding protein [KO:K02031]
LUW96_23065  ABC transporter ATP-binding protein [KO:K02031]
LUW96_25855  ABC transporter ATP-binding protein [KO:K02031]
LUW96_25975  ABC transporter ATP-binding protein [KO:K02031]
LUW96_14435  ABC transporter ATP-binding protein [KO:K02032]
LUW96_21350  ABC transporter ATP-binding protein [KO:K02032]
LUW96_23070  ATP-binding cassette domain-containing protein [KO:K02032]
LUW96_25850  ABC transporter ATP-binding protein [KO:K02032]
LUW96_25970  ABC transporter ATP-binding protein [KO:K02032]
LUW96_06540  yidC; membrane protein insertase YidC [KO:K03217]
LUW96_07940  secE; preprotein translocase subunit SecE [KO:K03073]
LUW96_03675  secG; preprotein translocase subunit SecG [KO:K03075]
LUW96_04270  secY; preprotein translocase subunit SecY [KO:K03076]
LUW96_12780  yajC; preprotein translocase subunit YajC [KO:K03210]
LUW96_11240  secA; preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
LUW96_04925  ftsY; signal recognition particle-docking protein FtsY [KO:K03110]
LUW96_05755  secB; protein-export chaperone SecB [KO:K03071]
LUW96_00120  ffh; signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
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Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
PMID:17376080
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
PMID:21622734
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
PMID:21504831
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
PMID:16513747
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
PMID:20514483
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
PMID:26579084
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
PMID:18851841
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
PMID:25714717
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
DOI:10.1128/mBio.02569-14
Reference
PMID:25824838
  Authors
Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
  Journal
Infect Immun 83:2430-42 (2015)
DOI:10.1128/IAI.00240-15
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Related
pathway
kpas00405  Phenazine biosynthesis
kpas02040  Flagellar assembly
KO pathway
ko02024   
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