Entry
Name
Pyrimidine metabolism - Klebsiella pneumoniae subsp. rhinoscleromatis SB3432
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
Ortholog table
Module
kpr_M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:kpr00240 ]
Other DBs
Organism
Klebsiella pneumoniae subsp. rhinoscleromatis SB3432 [GN:
kpr ]
Gene
KPR_0964 carB; highly similar to carbamoyl-phosphate synthase large chain from Salmonella typhimurium (sp [KO:K01955 ] [EC:6.3.5.5 ]
KPR_0963 carA; highly similar to carbamoyl-phosphate synthase small chain from Escherichia coli strain SMS-3-5 - SECEC (tr [KO:K01956 ] [EC:6.3.5.5 ]
KPR_0634 pyrB; highly similar to aspartate carbamoyltransferase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00609 ] [EC:2.1.3.2 ]
KPR_0633 pyrI; highly similar to aspartate carbamoyltransferase regulatory chain from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00610 ]
KPR_3407 unnamed protein product; highly similar to putative dihydroorotase from Escherichia coli (tr [KO:K01465 ] [EC:3.5.2.3 ]
KPR_2120 pyrC; highly similar to dihydroorotase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K01465 ] [EC:3.5.2.3 ]
KPR_0613 unnamed protein product; highly similar to putative amidohydrolase from Enterobacter sp. strain 638 (tr [KO:K01465 ] [EC:3.5.2.3 ]
KPR_1658 pyrD; highly similar to dihydroorotate dehydrogenase from Klebsiella pneumoniae strain 342 (sp [KO:K00254 ] [EC:1.3.5.2 ]
KPR_4930 pyrE; highly similar to orotate phosphoribosyltransferase from Klebsiella pneumoniae strain 342 (sp [KO:K00762 ] [EC:2.4.2.10 ]
KPR_2329 pyrF; highly similar to orotidine 5'-phosphate decarboxylase from Klebsiella pneumoniae strain 342 (sp [KO:K01591 ] [EC:4.1.1.23 ]
KPR_1115 pyrH; highly similar to uridylate kinase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K09903 ] [EC:2.7.4.22 ]
KPR_1428 ndk; highly similar to nucleoside diphosphate kinase from Klebsiella pneumoniae strain 342 (sp [KO:K00940 ] [EC:2.7.4.6 ]
KPR_4134 mazG; highly similar to MazG family protein from Escherichia coli strain SMS-3-5 - SECEC (tr [KO:K04765 ] [EC:3.6.1.9 ]
KPR_4842 yhdE; highly similar to Maf-like protein YhdE from Salmonella typhimurium (sp [KO:K06287 ] [EC:3.6.1.-]
KPR_4718 ygjP; highly similar to putative uncharacterized protein YgjP from Escherichia coli strain UTI89 - UPEC (tr [KO:K07043 ] [EC:3.6.1.-]
KPR_4133 pyrG; highly similar to CTP synthase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K01937 ] [EC:6.3.4.2 ]
KPR_3641 cmk; highly similar to cytidylate kinase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00945 ] [EC:2.7.4.25 ]
KPR_2256 unnamed protein product; highly similar to pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase from Escherichia coli 83972 (tr [KO:K08320 ] [EC:3.6.1.65 ]
KPR_3883 nagD; highly similar to N-acetylglucosamine metabolism from Escherichia coli strain UTI89 - UPEC (tr [KO:K02566 ] [EC:3.1.3.5 ]
KPR_0908 yjjG; highly similar to putative uncharacterized protein YjjG from Escherichia coli O6 (tr [KO:K08723 ] [EC:3.1.3.-]
KPR_0277 udp; highly similar to uridine phosphorylase from Klebsiella aerogenes (sp [KO:K00757 ] [EC:2.4.2.3 ]
KPR_4389 unnamed protein product; highly similar to UPF0345 protein KPK_4351 from Klebsiella pneumoniae strain 342 (sp [KO:K09913 ] [EC:2.4.2.1 2.4.2.2 ]
KPR_1883 upp; highly similar to uracil phosphoribosyltransferase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00761 ] [EC:2.4.2.9 ]
KPR_0583 cpdB; highly similar to putative 2',3'-cyclic-nucleotide 2'-phosphodiesterase from Salmonella enterica (tr [KO:K01119 ] [EC:3.1.4.16 3.1.3.6 ]
KPR_2943 rihA; highly similar to pyrimidine-specific ribonucleoside hydrolase RihA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K01250 ] [EC:3.2.2.-]
KPR_0958 rihC; highly similar to non-specific ribonucleoside hydrolase RihC from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K12700 ] [EC:3.2.2.-]
KPR_4147 ygdH; highly similar to putative uncharacterized protein YgdH from Escherichia coli strain UTI89 - UPEC (tr [KO:K06966 ] [EC:3.2.2.10 3.2.2.-]
KPR_1509 cdd; highly similar to cytidine deaminase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K01489 ] [EC:3.5.4.5 ]
KPR_0719 unnamed protein product; highly similar to N-isopropylammelide isopropylaminohydrolase from Escherichia coli strain ATCC 8739 - DSM 1576 - Crooks (tr [KO:K01485 ] [EC:3.5.4.1 3.5.4.21 ]
KPR_0622 nrdD; highly similar to putative anaerobic ribonucleoside triphosphate reductase; [Salmonella paratyphi C (tr [KO:K21636 ] [EC:1.1.98.6 ]
KPR_2071 nrdA; highly similar to ribonucleoside-diphosphate reductase 1 subunit alpha from Salmonella typhimurium (sp [KO:K00525 ] [EC:1.17.4.1 ]
KPR_1283 nrdE; highly similar to ribonucleoside-diphosphate reductase from Escherichia coli O150:H5 strain SE15 (tr [KO:K00525 ] [EC:1.17.4.1 ]
KPR_2070 nrdB; highly similar to ribonucleotide-diphosphate reductase beta subunit from Escherichia coli O1:K1 - APEC (tr [KO:K00526 ] [EC:1.17.4.1 ]
KPR_1282 nrdF; highly similar to ribonucleoside-diphosphate reductase 2 subunit beta from Salmonella typhimurium (sp [KO:K00526 ] [EC:1.17.4.1 ]
KPR_2024 unnamed protein product; highly similar to UPF0207 protein KPN78578_26370 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K08722 ] [EC:3.1.3.89 ]
KPR_2136 tmk; highly similar to thymidylate kinase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00943 ] [EC:2.7.4.9 ]
KPR_4933 dut; highly similar to deoxyuridine 5'-triphosphate nucleotidohydrolase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K01520 ] [EC:3.6.1.23 ]
KPR_0916 deoA; highly similar to thymidine phosphorylase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00758 ] [EC:2.4.2.4 ]
KPR_3119 tdk; highly similar to thymidine kinase from Escherichia coli strain UTI89 - UPEC (tr [KO:K00857 ] [EC:2.7.1.21 ]
KPR_1797 thyA; highly similar to thymidylate synthase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00560 ] [EC:2.1.1.45 ]
KPR_3617 unnamed protein product; similar to putative amidase, hydantoinase-carbamoylase family from Polaromonas naphthalenivorans (tr [KO:K06016 ] [EC:3.5.1.6 3.5.1.87 ]
KPR_3485 rutA; highly similar to putative monooxygenase RutA from Escherichia coli strain K12 (sp [KO:K09018 ] [EC:1.14.99.46 ]
KPR_3490 rutF; highly similar to predicted oxidoreductase, flavin:NADH component from Escherichia coli O1:K1 - APEC (tr [KO:K09024 ] [EC:1.5.1.-]
KPR_3486 unnamed protein product; highly similar to peroxyureidoacrylate-ureidoacrylate amidohydrolase RutB from Klebsiella variicola (sp [KO:K09020 ] [EC:3.5.1.110 ]
KPR_3487 rutC; highly similar to pyrimidine utilization protein C from Escherichia coli O44:H18 strain 042 - EAEC (tr [KO:K09021 ]
KPR_3488 rutD; similar to pyrimidine utilization protein RutD from Escherichia coli strain K12 (sp [KO:K09023 ] [EC:3.5.1.-]
KPR_2473 ydfG; highly similar to NADP-dependent L-serine-L-allo-threonine dehydrogenase YdfG from Escherichia coli O6 (sp [KO:K16066 ] [EC:1.1.1.381 1.1.1.-]
KPR_3489 rutE; highly similar to putative NADH dehydrogenase-NAD(P)H nitroreductase KPN78578_10080 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K09019 ] [EC:1.1.1.-]
Compound
C00119 5-Phospho-alpha-D-ribose 1-diphosphate
C00438 N-Carbamoyl-L-aspartate
C00672 2-Deoxy-D-ribose 1-phosphate
C01168 Pseudouridine 5'-phosphate
C01205 (R)-3-Amino-2-methylpropanoate
C03997 5-Hydroxymethyldeoxycytidylate
C06198 P1,P4-Bis(5'-uridyl) tetraphosphate
C11038 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
C11039 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
C15607 3-Oxo-3-ureidopropanoate
C20231 (Z)-3-Ureidoacrylate peracid
C20249 (Z)-3-Peroxyaminoacrylate
C20846 3-Oxo-3-ureidoisobutyrate
C21029 (R)-3-Ureidoisobutyrate
Related pathway
kpr00250 Alanine, aspartate and glutamate metabolism
kpr00280 Valine, leucine and isoleucine degradation
KO pathway
LinkDB
All DBs