KEGG   PATHWAY: lang00053
Entry
lang00053                   Pathway                                
Name
Ascorbate and aldarate metabolism - Lupinus angustifolius (narrow-leaved blue lupine)
Class
Metabolism; Carbohydrate metabolism
Pathway map
lang00053  Ascorbate and aldarate metabolism
lang00053

Module
lang_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:lang00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Lupinus angustifolius (narrow-leaved blue lupine) [GN:lang]
Gene
109347372  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
109357061  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
109333455  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
109341380  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
109353755  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
109360671  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
109356948  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
109349530  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
109354730  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
109344323  UDP-sugar pyrophosphorylase 1 [KO:K12447] [EC:2.7.7.64]
109347257  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
109351091  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
109358081  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
109333731  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
109352391  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
109338107  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
109360811  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
109351477  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
109330986  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
109359420  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
109359521  aldose reductase-like [KO:K00002] [EC:1.1.1.2]
109352754  aldose reductase-like [KO:K00002] [EC:1.1.1.2]
109337326  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
109337324  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
109357115  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
109344618  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
109351734  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
109354284  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
109336358  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
109330267  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
109361102  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
109338702  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
109334908  inositol-phosphate phosphatase-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
109362898  inositol-phosphate phosphatase-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
109327793  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
109331942  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
109336341  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
109344108  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
109350406  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
109362822  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
109327878  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
109331317  UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
109348922  UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
109350023  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
109346694  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
109360343  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
109355211  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
109362741  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
109336207  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
109354873  monodehydroascorbate reductase 4, peroxisomal-like [KO:K08232] [EC:1.6.5.4]
109337387  monodehydroascorbate reductase 5, mitochondrial [KO:K08232] [EC:1.6.5.4]
109348332  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
109334795  monodehydroascorbate reductase-like [KO:K08232] [EC:1.6.5.4]
109347278  monodehydroascorbate reductase 4, peroxisomal [KO:K08232] [EC:1.6.5.4]
109363606  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
109348741  probable L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
109328226  probable L-ascorbate peroxidase 6, chloroplastic [KO:K00434] [EC:1.11.1.11]
109351626  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
109328584  probable L-ascorbate peroxidase 6, chloroplastic [KO:K00434] [EC:1.11.1.11]
109355353  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
109325078  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
109332963  L-ascorbate peroxidase 3, peroxisomal-like [KO:K00434] [EC:1.11.1.11]
109343738  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
109353210  L-ascorbate peroxidase 3, peroxisomal-like [KO:K00434] [EC:1.11.1.11]
109344314  probable L-ascorbate peroxidase 6, chloroplastic [KO:K00434] [EC:1.11.1.11]
109355503  L-ascorbate peroxidase 3, peroxisomal-like [KO:K00434] [EC:1.11.1.11]
109335897  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
109345126  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
109354486  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
109359087  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
109330592  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
109331691  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
109349587  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
109332114  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
109344964  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
109331912  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
109349522  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
109344096  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
109344097  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
109327179  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
109327180  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
109333428  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
109360260  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
109332944  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
109343374  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
109350163  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
109357703  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
109337765  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
109331610  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
109351565  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
109362731  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
109326919  aldehyde dehydrogenase family 7 member A1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
lang00020  Citrate cycle (TCA cycle)
lang00040  Pentose and glucuronate interconversions
lang00051  Fructose and mannose metabolism
lang00520  Amino sugar and nucleotide sugar metabolism
lang00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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