KEGG   PATHWAY: lmd00630
Entry
lmd00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Leisingera methylohalidivorans
Class
Metabolism; Carbohydrate metabolism
Pathway map
lmd00630  Glyoxylate and dicarboxylate metabolism
lmd00630

Module
lmd_M00373  Ethylmalonyl pathway [PATH:lmd00630]
lmd_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:lmd00630]
Other DBs
GO: 0046487 0043648
Organism
Leisingera methylohalidivorans [GN:lmd]
Gene
METH_07710  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
METH_12200  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
METH_23135  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
METH_12390  malate synthase [KO:K01638] [EC:2.3.3.9]
METH_03295  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
METH_08955  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
METH_08010  aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
METH_18370  succinyl-CoA synthetase subunit alpha [KO:K08692] [EC:6.2.1.9]
METH_18375  sucC; malate--CoA ligase subunit beta [KO:K14067] [EC:6.2.1.9]
METH_03175  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
METH_21075  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
METH_19140  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
METH_07180  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
METH_03170  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
METH_04850  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
METH_03410  crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
METH_05130  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
METH_03400  protein meaA [KO:K14447] [EC:5.4.99.63]
METH_00815  acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
METH_03330  MaoC family dehydratase [KO:K14449] [EC:4.2.1.148]
METH_18390  Malyl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
METH_02340  Malyl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
METH_03315  (3S)-malyl-CoA thiolesterase [KO:K14451] [EC:3.1.2.30]
METH_06150  acetyl-CoA carboxylase [KO:K01965] [EC:6.4.1.3]
METH_06110  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
METH_06170  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
METH_15355  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
METH_15350  2-hydroxy-acid oxidase [KO:K11472] [EC:1.1.99.14]
METH_15345  2-hydroxy-acid oxidase [KO:K11473] [EC:1.1.99.14]
METH_03915  2-hydroxyacid dehydrogenase [KO:K00015] [EC:1.1.1.26]
METH_01690  hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
METH_14040  2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
METH_01240  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
METH_12225  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
METH_13240  phosphatase [KO:K01091] [EC:3.1.3.18]
METH_23280  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
METH_03570  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
METH_03670  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
METH_06515  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
METH_06525  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
METH_16555  glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
METH_08080  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
METH_14055  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
METH_18430  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
METH_07080  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
METH_18355  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
METH_14670  hypothetical protein [KO:K00605] [EC:2.1.2.10]
METH_14625  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
METH_18405  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
METH_18460  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
METH_03255  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
METH_14605  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
METH_21160  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
METH_09160  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
METH_14630  glycine cleavage system protein H [KO:K02437]
METH_14050  glycine cleavage system protein H [KO:K02437]
METH_18395  hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
METH_16230  ketohydroxyglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
METH_14855  ketohydroxyglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
METH_01490  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
METH_17645  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
METH_01480  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
METH_18080  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
METH_18085  NADH-quinone oxidoreductase subunit F [KO:K22515] [EC:1.17.1.9]
METH_01475  formate dehydrogenase subunit beta [KO:K00124]
METH_01470  ATP synthase subunit E [KO:K00127]
METH_15320  esterase [KO:K01432] [EC:3.5.1.9]
METH_21710  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
lmd00010  Glycolysis / Gluconeogenesis
lmd00020  Citrate cycle (TCA cycle)
lmd00030  Pentose phosphate pathway
lmd00053  Ascorbate and aldarate metabolism
lmd00071  Fatty acid degradation
lmd00230  Purine metabolism
lmd00250  Alanine, aspartate and glutamate metabolism
lmd00260  Glycine, serine and threonine metabolism
lmd00620  Pyruvate metabolism
lmd00710  Carbon fixation by Calvin cycle
lmd00750  Vitamin B6 metabolism
lmd00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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