KEGG   PATHWAY: mgad00230
Entry
mgad00230                   Pathway                                
Name
Purine metabolism - Mycolicibacterium gadium
Class
Metabolism; Nucleotide metabolism
Pathway map
mgad00230  Purine metabolism
mgad00230

Module
mgad_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mgad00230]
mgad_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mgad00230]
mgad_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mgad00230]
mgad_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mgad00230]
mgad_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mgad00230]
Other DBs
GO: 0006163 0042278
Organism
Mycolicibacterium gadium [GN:mgad]
Gene
MGAD_20280  pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
MGAD_31070  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MGAD_35740  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MGAD_36120  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
MGAD_32860  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MGAD_47870  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
MGAD_35820  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
MGAD_35920  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
MGAD_35910  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MGAD_35710  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
MGAD_25360  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
MGAD_25350  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MGAD_36010  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MGAD_36060  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MGAD_32850  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MGAD_13600  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MGAD_17360  haloacid dehalogenase [KO:K02566] [EC:3.1.3.5]
MGAD_25820  punA; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
MGAD_04780  laccase domain protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MGAD_26440  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
MGAD_38270  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MGAD_26570  putative oxidoreductase [KO:K00088] [EC:1.1.1.205]
MGAD_26580  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
MGAD_00610  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MGAD_55820  rdgB; non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
MGAD_09140  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
MGAD_26520  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
MGAD_07660  inosine 5-monophosphate dehydrogenase [KO:K26110] [EC:1.7.1.7]
MGAD_12540  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MGAD_19030  nrdE; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
MGAD_18910  nrdF2; ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MGAD_21570  R2-like ligand binding oxidase [KO:K00526] [EC:1.17.4.1]
MGAD_01850  dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
MGAD_13590  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MGAD_30960  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MGAD_49220  hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MGAD_52130  hypothetical protein [KO:K07816] [EC:2.7.6.5]
MGAD_04220  hypothetical protein [KO:K01768] [EC:4.6.1.1]
MGAD_05150  cya; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MGAD_18720  cyclase [KO:K01768] [EC:4.6.1.1]
MGAD_26700  hypothetical protein [KO:K01768] [EC:4.6.1.1]
MGAD_33740  hypothetical protein [KO:K01768] [EC:4.6.1.1]
MGAD_38450  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MGAD_50760  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MGAD_54550  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MGAD_55550  hypothetical protein [KO:K01768] [EC:4.6.1.1]
MGAD_55990  putative adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MGAD_47790  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
MGAD_04320  adenosine kinase [KO:K00856] [EC:2.7.1.20]
MGAD_25920  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MGAD_27550  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
MGAD_31010  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
MGAD_13950  diadenosine polyphosphate hydrolase [KO:K19710] [EC:2.7.7.53]
MGAD_54980  cysNC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
MGAD_54970  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
MGAD_38320  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
MGAD_35110  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
MGAD_35100  allantoinase [KO:K16842] [EC:3.5.2.5]
MGAD_35090  alc; putative allantoicase [KO:K01477] [EC:3.5.3.4]
MGAD_07750  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
MGAD_07740  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
MGAD_07730  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
MGAD_22410  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mgad00030  Pentose phosphate pathway
mgad00220  Arginine biosynthesis
mgad00250  Alanine, aspartate and glutamate metabolism
mgad00260  Glycine, serine and threonine metabolism
mgad00340  Histidine metabolism
mgad00630  Glyoxylate and dicarboxylate metabolism
mgad00730  Thiamine metabolism
mgad00740  Riboflavin metabolism
mgad00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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