KEGG   PATHWAY: msho00630
Entry
msho00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium shottsii
Class
Metabolism; Carbohydrate metabolism
Pathway map
msho00630  Glyoxylate and dicarboxylate metabolism
msho00630

Module
msho_M00012  Glyoxylate cycle [PATH:msho00630]
msho_M00621  Glycine cleavage system [PATH:msho00630]
msho_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:msho00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium shottsii [GN:msho]
Gene
MSHO_25370  aceA_1; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MSHO_42290  aceA_2; isocitrate lyase 2 [KO:K01637] [EC:4.1.3.1]
MSHO_11030  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
MSHO_40510  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MSHO_15840  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MSHO_56940  gltA2; citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
MSHO_56970  citA; putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MSHO_58940  citrate synthase [KO:K01647] [EC:2.3.3.1]
MSHO_35260  acn; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
MSHO_57330  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_61640  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_00130  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_00630  fadA4; putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_01680  fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_03520  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_05060  fadA5; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_05270  fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_18830  fadA2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_22700  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_40970  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MSHO_00640  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MSHO_60610  accA3; acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MSHO_60560  accD5; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MSHO_60570  hypothetical protein [KO:K27095]
MSHO_47520  accD6; putative propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MSHO_35460  mutA; putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MSHO_35470  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
MSHO_58140  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
MSHO_58150  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
MSHO_48230  dehydrogenase [KO:K00104] [EC:1.1.99.14]
MSHO_16060  oxidoreductase [KO:K00104] [EC:1.1.99.14]
MSHO_51080  srpA; catalase-related peroxidase [KO:K03781] [EC:1.11.1.6]
MSHO_10400  katA; catalase [KO:K03781] [EC:1.11.1.6]
MSHO_47160  hypothetical protein [KO:K01091] [EC:3.1.3.18]
MSHO_41360  glnA3; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
MSHO_46930  glnA1; glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
MSHO_47000  glnA2; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
MSHO_01480  glyA1; serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
MSHO_12440  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
MSHO_12470  gcvP_1; glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MSHO_40400  gcvP_2; putative glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
MSHO_12460  gcvT_1; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MSHO_46700  gcvT_2; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
MSHO_25300  lpd; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MSHO_12450  gcvH_1; glycine cleavage system H protein [KO:K02437]
MSHO_40350  gcvH_2; glycine cleavage system H protein [KO:K02437]
MSHO_46620  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MSHO_15880  kgd; multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MSHO_44800  cupin [KO:K01569] [EC:4.1.1.2]
MSHO_10620  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
MSHO_10610  4Fe-4S ferredoxin [KO:K00124]
MSHO_54920  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
MSHO_13680  oxcA; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
msho00010  Glycolysis / Gluconeogenesis
msho00020  Citrate cycle (TCA cycle)
msho00030  Pentose phosphate pathway
msho00053  Ascorbate and aldarate metabolism
msho00071  Fatty acid degradation
msho00230  Purine metabolism
msho00250  Alanine, aspartate and glutamate metabolism
msho00260  Glycine, serine and threonine metabolism
msho00620  Pyruvate metabolism
msho00710  Carbon fixation by Calvin cycle
msho00750  Vitamin B6 metabolism
msho00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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