KEGG   PATHWAY: mtd00230
Entry
mtd00230                    Pathway                                
Name
Purine metabolism - Mycobacterium tuberculosis UT205
Class
Metabolism; Nucleotide metabolism
Pathway map
mtd00230  Purine metabolism
mtd00230

Module
mtd_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mtd00230]
mtd_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mtd00230]
mtd_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mtd00230]
mtd_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mtd00230]
mtd_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mtd00230]
Other DBs
GO: 0006163 0042278
Organism
Mycobacterium tuberculosis UT205 [GN:mtd]
Gene
UDA_3068c  pgmA; pgmA [KO:K01835] [EC:5.4.2.2]
UDA_1017c  prsA; prsA [KO:K00948] [EC:2.7.6.1]
UDA_0808  purF; purF [KO:K00764] [EC:2.4.2.14]
UDA_0772  purD; purD [KO:K01945] [EC:6.3.4.13]
UDA_0956  purN; purN [KO:K11175] [EC:2.1.2.2]
UDA_0389  purT; purT [KO:K08289] [EC:6.3.1.21]
UDA_0803  purL; purL [KO:K23269] [EC:6.3.5.3]
UDA_0787A  unnamed protein product [KO:K23264] [EC:6.3.5.3]
UDA_0788  purQ; purQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
UDA_0809  purM; purM [KO:K01933] [EC:6.3.3.1]
UDA_3276c  purK; purK [KO:K01589] [EC:6.3.4.18]
UDA_3275c  purE; purE [KO:K01588] [EC:5.4.99.18]
UDA_0780  purC; purC [KO:K01923] [EC:6.3.2.6]
UDA_0777  purB; purB [KO:K01756] [EC:4.3.2.2]
UDA_0957  purH; purH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
UDA_2584c  apt; apt [KO:K00759] [EC:2.4.2.7]
UDA_3307  deoD; deoD [KO:K03783] [EC:2.4.2.1]
UDA_2149c  yfiH; yfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
UDA_3393  iunH; iunH [KO:K01239] [EC:3.2.2.1]
UDA_3624c  hpt; hpt [KO:K00760] [EC:2.4.2.8]
UDA_3410c  guaB3; guaB3 [KO:K00088] [EC:1.1.1.205]
UDA_3411c  guaB2; guaB2 [KO:K00088] [EC:1.1.1.205]
UDA_2445c  ndkA; ndkA [KO:K00940] [EC:2.7.4.6]
UDA_1341  unnamed protein product [KO:K01519] [EC:3.6.1.66]
UDA_3396c  guaA; guaA [KO:K01951] [EC:6.3.5.2]
UDA_1843c  guaB1; guaB1 [KO:K26110] [EC:1.7.1.7]
UDA_1389  gmk; gmk [KO:K00942] [EC:2.7.4.8]
UDA_3051c  nrdE; nrdE [KO:K00525] [EC:1.17.4.1]
UDA_0570  nrdZ; nrdZ [KO:K00525] [EC:1.17.4.1]
UDA_3048c  nrdF2; nrdF2 [KO:K00526] [EC:1.17.4.1]
UDA_0233  nrdB; nrdB [KO:K00526] [EC:1.17.4.1]
UDA_1981c  nrdF1; nrdF1 [KO:K00526] [EC:1.17.4.1]
UDA_2344c  dgt; dgt [KO:K01129] [EC:3.1.5.1]
UDA_2583c  relA; relA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
UDA_0496  unnamed protein product [KO:K01524] [EC:3.6.1.11 3.6.1.40]
UDA_1026  unnamed protein product [KO:K01524] [EC:3.6.1.11 3.6.1.40]
UDA_1264  unnamed protein product [KO:K01768] [EC:4.6.1.1]
UDA_1625c  cya; cya [KO:K01768] [EC:4.6.1.1]
UDA_3645  unnamed protein product [KO:K01768] [EC:4.6.1.1]
UDA_0357c  purA; purA [KO:K01939] [EC:6.3.4.4]
UDA_2202c  cbhK; cbhK [KO:K00856] [EC:2.7.1.20]
UDA_3313c  add; add [KO:K01488] [EC:3.5.4.4]
UDA_0733  adk; adk [KO:K00939] [EC:2.7.4.3]
UDA_1021  unnamed protein product [KO:K04765] [EC:3.6.1.9]
UDA_0805  unnamed protein product [KO:K03651] [EC:3.1.4.53]
UDA_2613c  unnamed protein product [KO:K19710] [EC:2.7.7.53]
UDA_1286  cysN; cysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
UDA_1285  cysD; cysD [KO:K00957] [EC:2.7.7.4]
UDA_1850  ureC; ureC [KO:K01428] [EC:3.5.1.5]
UDA_1849  ureB; ureB [KO:K01429] [EC:3.5.1.5]
UDA_1848  ureA; ureA [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mtd00030  Pentose phosphate pathway
mtd00220  Arginine biosynthesis
mtd00250  Alanine, aspartate and glutamate metabolism
mtd00260  Glycine, serine and threonine metabolism
mtd00340  Histidine metabolism
mtd00630  Glyoxylate and dicarboxylate metabolism
mtd00730  Thiamine metabolism
mtd00740  Riboflavin metabolism
mtd00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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