KEGG   PATHWAY: mtg00230
Entry
mtg00230                    Pathway                                
Name
Purine metabolism - Mycobacterium tuberculosis RGTB327
Class
Metabolism; Nucleotide metabolism
Pathway map
mtg00230  Purine metabolism
mtg00230

Module
mtg_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mtg00230]
mtg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mtg00230]
mtg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mtg00230]
Other DBs
GO: 0006163 0042278
Organism
Mycobacterium tuberculosis RGTB327 [GN:mtg]
Gene
MRGA327_18865  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
MRGA327_06385  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MRGA327_05060  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MRGA327_06010  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MRGA327_02460  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
MRGA327_04915  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
MRGA327_04920  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MRGA327_20160  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
MRGA327_04860  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MRGA327_04840  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MRGA327_06015  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MRGA327_15915  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MRGA327_20365  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
MRGA327_13260  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MRGA327_20945  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
MRGA327_22325  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MRGA327_21040  inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
MRGA327_21045  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
MRGA327_15085  ndk; mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase [KO:K00940] [EC:2.7.4.6]
MRGA327_08405  dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
MRGA327_20965  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
MRGA327_11405  inosine 5-monophosphate dehydrogenase [KO:K26110] [EC:1.7.1.7]
MRGA327_08705  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MRGA327_18745  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
MRGA327_01480  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MRGA327_12190  nrdF1; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MRGA327_14430  deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
MRGA327_06430  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MRGA327_03140  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MRGA327_07920  adenylyl cyclase [KO:K01768] [EC:4.6.1.1]
MRGA327_10080  membrane-anchored adenylyl cyclase CYA [KO:K01768] [EC:4.6.1.1]
MRGA327_20415  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MRGA327_04565  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
MRGA327_06405  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
MRGA327_05040  hypothetical protein [KO:K03651] [EC:3.1.4.53]
MRGA327_16095  hypothetical protein [KO:K19710] [EC:2.7.7.53]
MRGA327_08055  bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein [KO:K00955] [EC:2.7.7.4 2.7.1.25]
MRGA327_08050  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
MRGA327_11440  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
MRGA327_11435  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
MRGA327_11430  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mtg00030  Pentose phosphate pathway
mtg00220  Arginine biosynthesis
mtg00250  Alanine, aspartate and glutamate metabolism
mtg00260  Glycine, serine and threonine metabolism
mtg00340  Histidine metabolism
mtg00630  Glyoxylate and dicarboxylate metabolism
mtg00730  Thiamine metabolism
mtg00740  Riboflavin metabolism
mtg00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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