KEGG   PATHWAY: mtun00230
Entry
mtun00230                   Pathway                                
Name
Purine metabolism - Methylocella tundrae
Class
Metabolism; Nucleotide metabolism
Pathway map
mtun00230  Purine metabolism
mtun00230

Module
mtun_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mtun00230]
mtun_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mtun00230]
mtun_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mtun00230]
mtun_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mtun00230]
mtun_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mtun00230]
mtun_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mtun00230]
Other DBs
GO: 0006163 0042278
Organism
Methylocella tundrae [GN:mtun]
Gene
MTUNDRAET4_1288  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
MTUNDRAET4_2906  Phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
MTUNDRAET4_0215.1  Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MTUNDRAET4_0231  prsA; phosphoribosylpyrophosphate synthase [KO:K00948] [EC:2.7.6.1]
MTUNDRAET4_0849  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MTUNDRAET4_3966  purD; phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
MTUNDRAET4_0980  purN; phosphoribosylglycinamide formyltransferase 1 [KO:K11175] [EC:2.1.2.2]
MTUNDRAET4_0614  purL; Phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
MTUNDRAET4_0617  purS; Phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
MTUNDRAET4_0615  purQ; Phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MTUNDRAET4_0981  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
MTUNDRAET4_2594  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
MTUNDRAET4_2595  N5-carboxyaminoimidazole ribonucleotide mutase (modular protein) [KO:K01588] [EC:5.4.99.18]
MTUNDRAET4_3342  purC; putative phosphoribosylaminoimidazole-succinocarboxamide synthase 2 [KO:K01923] [EC:6.3.2.6]
MTUNDRAET4_0618  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase A [KO:K01923] [EC:6.3.2.6]
MTUNDRAET4_0729  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MTUNDRAET4_3579  purH; fused IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MTUNDRAET4_3688  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MTUNDRAET4_4003  surE; broad specificity 5'(3')-nucleotidase and polyphosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
MTUNDRAET4_0679  Polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MTUNDRAET4_4024  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
MTUNDRAET4_0979  putative Nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MTUNDRAET4_3683  dITP/XTP pyrophosphatase (fragment) [KO:K01519] [EC:3.6.1.66]
MTUNDRAET4_2029  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
MTUNDRAET4_1544  conserved protein of unknown function [KO:K11177] [EC:1.17.1.4]
MTUNDRAET4_1543  yagS; putative oxidoreductase with FAD-binding domain [KO:K11178] [EC:1.17.1.4]
MTUNDRAET4_1542  (2Fe-2S)-binding protein [KO:K13483]
MTUNDRAET4_2873  Glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
MTUNDRAET4_1654  guaA; GMP synthetase (glutamine aminotransferase) [KO:K01951] [EC:6.3.5.2]
MTUNDRAET4_1393  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MTUNDRAET4_0019.2  nrdA; Ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
MTUNDRAET4_0273.1  Vitamin B12-dependent ribonucleotide reductase (fragment) [KO:K00525] [EC:1.17.4.1]
MTUNDRAET4_0243  nrdJ; Vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
MTUNDRAET4_0020.2  nrdB; ribonucleoside-diphosphate reductase, beta subunit [KO:K00526] [EC:1.17.4.1]
MTUNDRAET4_1080  Deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
MTUNDRAET4_0049.2  conserved protein of unknown function [KO:K06952] [EC:3.1.3.89]
MTUNDRAET4_0719  protein of unknown function [KO:K06952] [EC:3.1.3.89]
MTUNDRAET4_1400  rsh; GTP pyrophosphokinase rsh [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MTUNDRAET4_4020  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MTUNDRAET4_1295  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MTUNDRAET4_0115  Family 3 adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MTUNDRAET4_3141  Adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MTUNDRAET4_0485  Ferredoxin [KO:K01768] [EC:4.6.1.1]
MTUNDRAET4_0823  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
MTUNDRAET4_3757  ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K09769] [EC:3.1.4.16]
MTUNDRAET4_1471  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
MTUNDRAET4_1127  mazG; Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
MTUNDRAET4_2399  nodQ; Sulfate adenylyltransferase subunit 1 / Adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
MTUNDRAET4_2398  cysD; sulfate adenylyltransferase subunit 2 (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase small subunit) [KO:K00957] [EC:2.7.7.4]
MTUNDRAET4_2851  ureC; urease alpha subunit [KO:K01428] [EC:3.5.1.5]
MTUNDRAET4_1848  ureC; Urease subunit alpha 1 [KO:K01428] [EC:3.5.1.5]
MTUNDRAET4_2850  ureB; urease beta subunit [KO:K01429] [EC:3.5.1.5]
MTUNDRAET4_2849  ureA; urease gamma subunit [KO:K01430] [EC:3.5.1.5]
MTUNDRAET4_1849  ureAB; Urease subunit gamma/beta [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mtun00030  Pentose phosphate pathway
mtun00220  Arginine biosynthesis
mtun00250  Alanine, aspartate and glutamate metabolism
mtun00260  Glycine, serine and threonine metabolism
mtun00340  Histidine metabolism
mtun00630  Glyoxylate and dicarboxylate metabolism
mtun00730  Thiamine metabolism
mtun00740  Riboflavin metabolism
mtun00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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