KEGG   PATHWAY: nad00630
Entry
nad00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Nocardia asteroides
Class
Metabolism; Carbohydrate metabolism
Pathway map
nad00630  Glyoxylate and dicarboxylate metabolism
nad00630

Module
nad_M00012  Glyoxylate cycle [PATH:nad00630]
nad_M00621  Glycine cleavage system [PATH:nad00630]
nad_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:nad00630]
Other DBs
GO: 0046487 0043648
Organism
Nocardia asteroides [GN:nad]
Gene
NCTC11293_00165  aceA; Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
NCTC11293_01095  acs_1; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
NCTC11293_02849  acsA_1; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
NCTC11293_05361  acs_3; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
NCTC11293_03742  glcB_2; Malate synthase G [KO:K01638] [EC:2.3.3.9]
NCTC11293_05012  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NCTC11293_01461  citA; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
NCTC11293_01464  gltA2; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
NCTC11293_05411  gltA; Citrate synthase [KO:K01659] [EC:2.3.3.5]
NCTC11293_04855  acnA; Aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
NCTC11293_00505  fadI_1; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NCTC11293_00666  Probable acetyl-CoA acyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC11293_01029  fadA_2; Putative acyltransferase Rv0859 [KO:K00626] [EC:2.3.1.9]
NCTC11293_01261  pcaF_1; Beta-ketoadipyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NCTC11293_01278  fadA_3; Putative acyltransferase Rv0859 [KO:K00626] [EC:2.3.1.9]
NCTC11293_01282  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC11293_01962  Probable acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC11293_03263  thlA_1; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC11293_03312  bktB; Beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
NCTC11293_04090  fadA_5; Putative acyltransferase Rv0859 [KO:K00626] [EC:2.3.1.9]
NCTC11293_06195  thlA_2; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NCTC11293_01961  4-hydroxyphenylpyruvate dioxygenase and related hemolysins [KO:K05606] [EC:5.1.99.1]
NCTC11293_01839  accA1_2; Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
NCTC11293_01844  accD5_3; Probable propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
NCTC11293_02579  accD5_4; Probable propionyl-CoA carboxylase beta chain 5 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
NCTC11293_03819  mutA; Methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
NCTC11293_03820  mutB; Methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
NCTC11293_01866  Uncharacterized FAD-linked oxidoreductase Rv2280 [KO:K00104] [EC:1.1.99.14]
NCTC11293_01070  katA; Catalase [KO:K03781] [EC:1.11.1.6]
NCTC11293_03226  katE; Catalase HPII [KO:K03781] [EC:1.11.1.6]
NCTC11293_02233  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
NCTC11293_04331  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
NCTC11293_05310  phnX; Phosphonoacetaldehyde hydrolase [KO:K01091] [EC:3.1.3.18]
NCTC11293_03969  cbbL; Ribulose bisphosphate carboxylase large chain [KO:K01601] [EC:4.1.1.39]
NCTC11293_03970  cbxSC; Ribulose bisphosphate carboxylase small chain, chromosomal [KO:K01602] [EC:4.1.1.39]
NCTC11293_02614  glnA_1; Probable glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
NCTC11293_02631  glnA_2; Glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
NCTC11293_03477  glnA_3; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
NCTC11293_06151  glyA1; Pyridoxal-phosphate-dependent serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
NCTC11293_03730  gcvP; Glycine dehydrogenase [decarboxylating] [KO:K00281] [EC:1.4.4.2]
NCTC11293_02740  gcvT; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
NCTC11293_00201  lpd; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NCTC11293_03724  gcvH; Glycine cleavage system H protein [KO:K02437]
NCTC11293_03314  Hgd_1; 2-(hydroxymethyl)glutarate dehydrogenase [KO:K00042] [EC:1.1.1.60]
NCTC11293_00554  glxK; Glycerate kinase [KO:K00865] [EC:2.7.1.165]
NCTC11293_03046  eda; Putative KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
NCTC11293_05991  kgd; 2-oxoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
NCTC11293_00140  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
nad00010  Glycolysis / Gluconeogenesis
nad00020  Citrate cycle (TCA cycle)
nad00030  Pentose phosphate pathway
nad00053  Ascorbate and aldarate metabolism
nad00071  Fatty acid degradation
nad00230  Purine metabolism
nad00250  Alanine, aspartate and glutamate metabolism
nad00260  Glycine, serine and threonine metabolism
nad00620  Pyruvate metabolism
nad00710  Carbon fixation by Calvin cycle
nad00750  Vitamin B6 metabolism
nad00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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