KEGG   PATHWAY: ncy00630
Entry
ncy00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Nocardia cyriacigeorgica
Class
Metabolism; Carbohydrate metabolism
Pathway map
ncy00630  Glyoxylate and dicarboxylate metabolism
ncy00630

Module
ncy_M00012  Glyoxylate cycle [PATH:ncy00630]
ncy_M00621  Glycine cleavage system [PATH:ncy00630]
ncy_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:ncy00630]
Other DBs
GO: 0046487 0043648
Organism
Nocardia cyriacigeorgica [GN:ncy]
Gene
NOCYR_5051  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
NOCYR_0331  ascA; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
NOCYR_1904  acsA; Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme) [KO:K01895] [EC:6.2.1.1]
NOCYR_3866  putative acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
NOCYR_2577  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
NOCYR_3552  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NOCYR_0665  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
NOCYR_0668  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
NOCYR_3909  prpC; Citrate synthase [KO:K01659] [EC:2.3.3.5]
NOCYR_2622  acnA; aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
NOCYR_0265  fadA; beta-ketoadipyl CoA thiolase [KO:K00626] [EC:2.3.1.9]
NOCYR_0518  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NOCYR_0530  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NOCYR_0534  putative lipid carrier protein or keto acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NOCYR_1610  lipid carrier protein or keto acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NOCYR_1155  phbA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NOCYR_2040  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NOCYR_2472  putative carnitinyl-CoA dehydratase (Crotonobetainyl-CoA hydratase) (modular protein) [KO:K00626] [EC:2.3.1.9]
NOCYR_2319  putative 3-ketoacyl-CoA thiolase 2, peroxisomal precursor (Beta-ketothiolase 2) (Acetyl-CoA acyltransferase 2) (Peroxisomal 3-oxoacyl-CoA thiolase 2) (Peroxisome defective protein 1) [KO:K00626] [EC:2.3.1.9]
NOCYR_4627  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NOCYR_5323  fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NOCYR_1154  mce; Methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
NOCYR_1052  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
NOCYR_1057  pccB; Propionyl-CoA carboxylase beta subunit [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
NOCYR_1673  pccB1; Propionyl-CoA carboxylase beta subunit [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
NOCYR_2640  mutA; methylmalonyl-CoA mutase beta subunit [KO:K01847] [EC:5.4.99.2]
NOCYR_2641  yliK; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
NOCYR_1071  putative oxidoreductase [KO:K00104] [EC:1.1.99.14]
NOCYR_0300  katA; Catalase (monofunctional heme-containing catalase) [KO:K03781] [EC:1.11.1.6]
NOCYR_2216  katA2; catalase (monofunctional heme-containing catalase) [KO:K03781] [EC:1.11.1.6]
NOCYR_3203  Putative hydrolase [KO:K01091] [EC:3.1.3.18]
NOCYR_3814  putative haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
NOCYR_3243  cbbL; Ribulose bisphosphate carboxylase large chain 2 (RuBisCO large subunit 2) [KO:K01601] [EC:4.1.1.39]
NOCYR_3242  Ribulose bisphosphate carboxylase small chain (RuBisCO small subunit) [KO:K01602] [EC:4.1.1.39]
NOCYR_1727  glnA; Glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NOCYR_1738  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
NOCYR_3021  glnA; Glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NOCYR_4589  glyA; Serine hydroxymethyltransferase (Serine methylase) (SHMT) [KO:K00600] [EC:2.1.2.1]
NOCYR_2568  gcvP; Glycine dehydrogenase [decarboxylating] (Glycine decarboxylase) (Glycine cleavage system P-protein) [KO:K00281] [EC:1.4.4.2]
NOCYR_1810  gcvT; Aminomethyltransferase (Glycine cleavage system T protein) [KO:K00605] [EC:2.1.2.10]
NOCYR_5082  lpd; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
NOCYR_2563  gcvH; Glycine cleavage system H protein [KO:K02437]
NOCYR_5372  glxK; Glycerate kinase [KO:K00865] [EC:2.7.1.165]
NOCYR_3761  Tartrate dehydrogenase/decarboxylase (TDH) (D-malate dehydrogenase [decarboxylating]) [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NOCYR_4437  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
NOCYR_5008  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ncy00010  Glycolysis / Gluconeogenesis
ncy00020  Citrate cycle (TCA cycle)
ncy00030  Pentose phosphate pathway
ncy00053  Ascorbate and aldarate metabolism
ncy00071  Fatty acid degradation
ncy00230  Purine metabolism
ncy00250  Alanine, aspartate and glutamate metabolism
ncy00260  Glycine, serine and threonine metabolism
ncy00620  Pyruvate metabolism
ncy00710  Carbon fixation by Calvin cycle
ncy00750  Vitamin B6 metabolism
ncy00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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