KEGG   PATHWAY: nfs00630
Entry
nfs00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Nonomuraea fuscirosea
Class
Metabolism; Carbohydrate metabolism
Pathway map
nfs00630  Glyoxylate and dicarboxylate metabolism
nfs00630

Module
nfs_M00012  Glyoxylate cycle [PATH:nfs00630]
nfs_M00621  Glycine cleavage system [PATH:nfs00630]
nfs_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:nfs00630]
Other DBs
GO: 0046487 0043648
Organism
Nonomuraea fuscirosea [GN:nfs]
Gene
OIE67_25600  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
OIE67_49430  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
OIE67_31455  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
OIE67_36550  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
OIE67_35070  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
OIE67_41435  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
OIE67_42530  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
OIE67_08860  citrate synthase [KO:K01647] [EC:2.3.3.1]
OIE67_17275  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
OIE67_25505  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
OIE67_41495  citrate synthase [KO:K01659] [EC:2.3.3.5]
OIE67_07695  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
OIE67_39830  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
OIE67_42460  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
OIE67_00290  acetyl-CoA synthetase [KO:K00626] [EC:2.3.1.9]
OIE67_00540  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
OIE67_54125  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
OIE67_19760  thiolase family protein [KO:K00626] [EC:2.3.1.9]
OIE67_36035  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
OIE67_37740  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
OIE67_05135  VOC family protein [KO:K05606] [EC:5.1.99.1]
OIE67_37745  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
OIE67_40955  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
OIE67_40725  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
OIE67_40730  acyl-CoA carboxylase subunit epsilon [KO:K27095]
OIE67_06700  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
OIE67_22425  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
OIE67_26635  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
OIE67_26640  methylmalonyl-CoA mutase subunit beta [KO:K01847] [EC:5.4.99.2]
OIE67_09130  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
OIE67_14070  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
OIE67_35075  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
OIE67_35080  FAD-binding oxidoreductase [KO:K11472] [EC:1.1.99.14]
OIE67_35085  heterodisulfide reductase-related iron-sulfur binding cluster [KO:K11473] [EC:1.1.99.14]
OIE67_45415  catalase [KO:K03781] [EC:1.11.1.6]
OIE67_01775  catalase [KO:K03781] [EC:1.11.1.6]
OIE67_51815  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
OIE67_23220  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
OIE67_32660  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
OIE67_08695  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
OIE67_27970  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
OIE67_29230  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
OIE67_29330  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
OIE67_31960  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
OIE67_37420  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
OIE67_08050  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
OIE67_37890  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
OIE67_23550  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
OIE67_37440  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
OIE67_51300  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
OIE67_29150  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
OIE67_37445  gcvH; glycine cleavage system protein GcvH [KO:K02437]
OIE67_34430  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
OIE67_00780  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
OIE67_34440  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
OIE67_00785  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
OIE67_34435  NAD(P)-dependent oxidoreductase [KO:K00042] [EC:1.1.1.60]
OIE67_28630  glycerate kinase [KO:K00865] [EC:2.7.1.165]
OIE67_52480  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
OIE67_25870  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
OIE67_25920  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
OIE67_00335  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
OIE67_50645  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
OIE67_50650  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
OIE67_12075  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
OIE67_14930  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
OIE67_50655  NADH-quinone oxidoreductase subunit F [KO:K00124]
OIE67_12070  4Fe-4S dicluster domain-containing protein [KO:K00124]
OIE67_50660  formate dehydrogenase subunit gamma [KO:K00127]
OIE67_15340  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
OIE67_05295  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
OIE67_15645  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
OIE67_34490  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
nfs00010  Glycolysis / Gluconeogenesis
nfs00020  Citrate cycle (TCA cycle)
nfs00030  Pentose phosphate pathway
nfs00053  Ascorbate and aldarate metabolism
nfs00071  Fatty acid degradation
nfs00230  Purine metabolism
nfs00250  Alanine, aspartate and glutamate metabolism
nfs00260  Glycine, serine and threonine metabolism
nfs00620  Pyruvate metabolism
nfs00710  Carbon fixation by Calvin cycle
nfs00750  Vitamin B6 metabolism
nfs00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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