KEGG   PATHWAY: nou00630
Entry
nou00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Natronococcus occultus
Class
Metabolism; Carbohydrate metabolism
Pathway map
nou00630  Glyoxylate and dicarboxylate metabolism
nou00630

Module
nou_M00621  Glycine cleavage system [PATH:nou00630]
nou_M00740  Methylaspartate cycle [PATH:nou00630]
nou_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:nou00630]
nou_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:nou00630]
Other DBs
GO: 0046487 0043648
Organism
Natronococcus occultus [GN:nou]
Gene
Natoc_1204  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
Natoc_2052  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
Natoc_3629  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
Natoc_1125  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Natoc_1127  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Natoc_0597  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
Natoc_1494  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
Natoc_4026  malate/lactate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Natoc_2190  citrate synthase [KO:K01647] [EC:2.3.3.1]
Natoc_2308  aconitase [KO:K01681] [EC:4.2.1.3]
Natoc_1554  aconitase [KO:K01681] [EC:4.2.1.3]
Natoc_1525  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Natoc_0546  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Natoc_2893  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Natoc_0758  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Natoc_3210  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Natoc_4292  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Natoc_4215  dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein [KO:K00023] [EC:1.1.1.36]
Natoc_1375  acyl dehydratase [KO:K17865] [EC:4.2.1.55]
Natoc_2976  acyl dehydratase [KO:K17865] [EC:4.2.1.55]
Natoc_1091  acyl dehydratase [KO:K17865] [EC:4.2.1.55]
Natoc_3595  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Natoc_1510  acyl dehydratase [KO:K14449] [EC:4.2.1.148]
Natoc_1449  acetyl/propionyl-CoA carboxylase, alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Natoc_1452  acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Natoc_1451  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
Natoc_0541  methylmalonyl-CoA mutase family protein [KO:K01849] [EC:5.4.99.2]
Natoc_3591  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
Natoc_1012  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
Natoc_1512  Glutamate mutase subunit E [KO:K19268] [EC:5.4.99.1]
Natoc_1513  glutamate mutase subunit S [KO:K01846] [EC:5.4.99.1]
Natoc_1511  methylaspartate ammonia-lyase [KO:K04835] [EC:4.3.1.2]
Natoc_1514  putative acyl-CoA transferase/carnitine dehydratase [KO:K19280] [EC:2.8.3.26]
Natoc_1509  citrate lyase beta subunit [KO:K19281] [EC:4.1.3.24]
Natoc_4308  citrate lyase beta subunit [KO:K19282] [EC:4.1.3.24 3.1.2.30]
Natoc_3642  catalase [KO:K03781] [EC:1.11.1.6]
Natoc_2031  putative phosphatase [KO:K01091] [EC:3.1.3.18]
Natoc_2792  putative phosphatase [KO:K01091] [EC:3.1.3.18]
Natoc_1316  haloacid dehalogenase superfamily enzyme, subfamily IA [KO:K01091] [EC:3.1.3.18]
Natoc_2642  sucrose-phosphate phosphatase-like hydrolase, Archaeal [KO:K22223] [EC:3.1.3.18]
Natoc_1744  serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Natoc_2112  glutamate synthase family protein [KO:K00284] [EC:1.4.7.1]
Natoc_3355  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Natoc_3304  glycine/serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Natoc_3112  glycine/serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Natoc_1537  glycine/serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Natoc_2849  glycine cleavage system protein P [KO:K00282] [EC:1.4.4.2]
Natoc_4334  glycine cleavage system protein P [KO:K00282] [EC:1.4.4.2]
Natoc_2848  glycine cleavage system protein P [KO:K00283] [EC:1.4.4.2]
Natoc_4335  glycine cleavage system protein P [KO:K00283] [EC:1.4.4.2]
Natoc_2385  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Natoc_2858  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Natoc_4332  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Natoc_3843  pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component [KO:K00382] [EC:1.8.1.4]
Natoc_4336  pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component [KO:K00382] [EC:1.8.1.4]
Natoc_2859  glycine cleavage system H protein [KO:K02437]
Natoc_4333  glycine cleavage system H protein [KO:K02437]
Natoc_4314  putative glycerate kinase [KO:K11529] [EC:2.7.1.165]
Natoc_1971  glycerol dehydrogenase-like oxidoreductase [KO:K26209] [EC:1.1.1.-]
Natoc_1855  haloacid dehalogenase superfamily enzyme, subfamily IA [KO:K26210] [EC:3.1.3.109]
Natoc_1263  ribulose-5-phosphate 4-epimerase-like epimerase or aldolase [KO:K01636] [EC:4.1.2.-]
Natoc_1854  ribulose-5-phosphate 4-epimerase-like epimerase or aldolase [KO:K01636] [EC:4.1.2.-]
Natoc_4310  isocitrate/isopropylmalate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Natoc_2545  2-keto-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Natoc_3317  putative anaerobic dehydrogenase [KO:K00123] [EC:1.17.1.9]
Natoc_0752  formate dehydrogenase, alpha subunit, archaeal-type [KO:K00123] [EC:1.17.1.9]
Natoc_2093  anaerobic dehydrogenase, typically selenocysteine-containing [KO:K00123] [EC:1.17.1.9]
Natoc_2094  Fe-S-cluster-containing hydrogenase subunit [KO:K00124]
Natoc_3316  Fe-S-cluster-containing hydrogenase subunit [KO:K00124]
Natoc_3303  formyltetrahydrofolate hydrolase [KO:K01433] [EC:3.5.1.10]
Natoc_0478  formyltetrahydrofolate hydrolase [KO:K01433] [EC:3.5.1.10]
Natoc_0098  putative acetamidase/formamidase [KO:K01455] [EC:3.5.1.49]
Natoc_4281  putative acetamidase/formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
nou00010  Glycolysis / Gluconeogenesis
nou00020  Citrate cycle (TCA cycle)
nou00030  Pentose phosphate pathway
nou00053  Ascorbate and aldarate metabolism
nou00071  Fatty acid degradation
nou00230  Purine metabolism
nou00250  Alanine, aspartate and glutamate metabolism
nou00260  Glycine, serine and threonine metabolism
nou00620  Pyruvate metabolism
nou00710  Carbon fixation by Calvin cycle
nou00750  Vitamin B6 metabolism
nou00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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