KEGG   PATHWAY: now00630
Entry
now00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Nonomuraea phyllanthi
Class
Metabolism; Carbohydrate metabolism
Pathway map
now00630  Glyoxylate and dicarboxylate metabolism
now00630

Module
now_M00012  Glyoxylate cycle [PATH:now00630]
now_M00621  Glycine cleavage system [PATH:now00630]
now_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:now00630]
Other DBs
GO: 0046487 0043648
Organism
Nonomuraea phyllanthi [GN:now]
Gene
GBF35_20300  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
GBF35_10075  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
GBF35_02025  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
GBF35_11205  malate synthase A [KO:K01638] [EC:2.3.3.9]
GBF35_05660  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
GBF35_31475  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
GBF35_35835  helix-turn-helix domain-containing protein [KO:K01647] [EC:2.3.3.1]
GBF35_04495  citrate synthase [KO:K01647] [EC:2.3.3.1]
GBF35_05615  citrate synthase [KO:K01659] [EC:2.3.3.5]
GBF35_37035  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
GBF35_43235  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
GBF35_25040  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GBF35_45055  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GBF35_14505  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
GBF35_04570  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GBF35_07145  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
GBF35_08760  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GBF35_39460  hypothetical protein [KO:K05606] [EC:5.1.99.1]
GBF35_08755  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
GBF35_13605  acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
GBF35_06045  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
GBF35_06285  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
GBF35_06280  acyl-CoA carboxylase subunit epsilon [KO:K27095]
GBF35_13360  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
GBF35_40150  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
GBF35_38100  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
GBF35_19390  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GBF35_19395  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GBF35_35580  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
GBF35_11200  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
GBF35_11195  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
GBF35_11190  4Fe-4S dicluster domain-containing protein [KO:K11473] [EC:1.1.99.14]
GBF35_37755  catalase [KO:K03781] [EC:1.11.1.6]
GBF35_27450  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
GBF35_47760  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
GBF35_30390  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
GBF35_06850  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
GBF35_16430  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
GBF35_20670  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
GBF35_17015  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GBF35_36015  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GBF35_09090  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GBF35_17085  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GBF35_18545  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GBF35_36635  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
GBF35_08605  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GBF35_21900  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
GBF35_09060  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
GBF35_48185  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GBF35_17170  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GBF35_09055  gcvH; glycine cleavage system protein GcvH [KO:K02437]
GBF35_11950  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
GBF35_11940  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
GBF35_13905  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
GBF35_13910  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
GBF35_11945  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
GBF35_17905  glycerate kinase [KO:K00865] [EC:2.7.1.165]
GBF35_20045  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GBF35_20115  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GBF35_15235  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GBF35_43515  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
GBF35_29430  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
GBF35_33390  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
GBF35_16055  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
GBF35_33395  4Fe-4S dicluster domain-containing protein [KO:K00124]
GBF35_39330  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
GBF35_11890  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
now00010  Glycolysis / Gluconeogenesis
now00020  Citrate cycle (TCA cycle)
now00030  Pentose phosphate pathway
now00053  Ascorbate and aldarate metabolism
now00071  Fatty acid degradation
now00230  Purine metabolism
now00250  Alanine, aspartate and glutamate metabolism
now00260  Glycine, serine and threonine metabolism
now00620  Pyruvate metabolism
now00710  Carbon fixation by Calvin cycle
now00750  Vitamin B6 metabolism
now00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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