KEGG   PATHWAY: obr00053
Entry
obr00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Oryza brachyantha (malo sina)
Class
Metabolism; Carbohydrate metabolism
Pathway map
obr00053  Ascorbate and aldarate metabolism
obr00053

Module
obr_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:obr00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Oryza brachyantha (malo sina) [GN:obr]
Gene
102708867  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
102723033  UDP-glucose 6-dehydrogenase 2 [KO:K00012] [EC:1.1.1.22]
102703473  UDP-glucose 6-dehydrogenase 3 [KO:K00012] [EC:1.1.1.22]
102707448  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
102707729  UDP-glucose 6-dehydrogenase 5 [KO:K00012] [EC:1.1.1.22]
102704348  UDP-sugar pyrophosphorylase [KO:K12447] [EC:2.7.7.64]
102700277  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
102721453  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
102708756  aldo-keto reductase family 4 member C10-like isoform X5 [KO:K00002] [EC:1.1.1.2]
102722494  aldose reductase [KO:K00002] [EC:1.1.1.2]
102709039  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
102709607  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
102710982  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
102704284  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
102714071  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
102717331  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
102715368  L-gulonolactone oxidase 5-like [KO:K00103] [EC:1.1.3.8]
102718199  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
102714961  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
102718679  GDP-mannose 3,5-epimerase 1 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
102720297  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
102721498  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
102720660  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
102705514  inositol monophosphatase 3 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
102719163  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
102719064  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
102701949  L-galactono-1,4-lactone dehydrogenase 2, mitochondrial isoform X1 [KO:K00225] [EC:1.3.2.3]
102720290  L-galactono-1,4-lactone dehydrogenase 2, mitochondrial isoform X1 [KO:K00225] [EC:1.3.2.3]
102720866  40S ribosomal protein S20-1-like [KO:K08679] [EC:5.1.3.6]
102705099  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
102720403  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
107303961  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
102701001  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
102721106  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
102704954  uncharacterized protein LOC102704954 [KO:K08232] [EC:1.6.5.4]
102710804  monodehydroascorbate reductase 5, chlorplastic [KO:K08232] [EC:1.6.5.4]
102719416  monodehydroascorbate reductase 4, cytosolic [KO:K08232] [EC:1.6.5.4]
102716626  monodehydroascorbate reductase 3, cytosolic [KO:K08232] [EC:1.6.5.4]
102713598  probable L-ascorbate peroxidase 8, chloroplastic [KO:K00434] [EC:1.11.1.11]
102702265  L-ascorbate peroxidase 1, cytosolic [KO:K00434] [EC:1.11.1.11]
102703203  probable L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
102702954  L-ascorbate peroxidase 2, cytosolic [KO:K00434] [EC:1.11.1.11]
102714726  probable L-ascorbate peroxidase 7, chloroplastic [KO:K00434] [EC:1.11.1.11]
102713566  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
102719916  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
102709006  probable glutathione S-transferase DHAR2, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
102719584  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
102718659  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
102702982  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
102718934  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
102704421  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
102709054  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
102711774  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
102712051  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
102706376  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
102704156  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
102712119  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
102718507  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
102721194  aldehyde dehydrogenase family 7 member A1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
obr00020  Citrate cycle (TCA cycle)
obr00040  Pentose and glucuronate interconversions
obr00051  Fructose and mannose metabolism
obr00520  Amino sugar and nucleotide sugar metabolism
obr00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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