KEGG   PATHWAY: palx00630
Entry
palx00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Ponticoccus alexandrii
Class
Metabolism; Carbohydrate metabolism
Pathway map
palx00630  Glyoxylate and dicarboxylate metabolism
palx00630

Module
palx_M00373  Ethylmalonyl pathway [PATH:palx00630]
palx_M00621  Glycine cleavage system [PATH:palx00630]
palx_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:palx00630]
Other DBs
GO: 0046487 0043648
Organism
Ponticoccus alexandrii [GN:palx]
Gene
GQA70_21350  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
GQA70_07115  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
GQA70_11135  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
GQA70_13855  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
GQA70_00135  malate synthase G [KO:K01638] [EC:2.3.3.9]
GQA70_15685  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
GQA70_23080  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
GQA70_08410  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
GQA70_12555  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
GQA70_23240  sucD; succinate--CoA ligase subunit alpha [KO:K08692] [EC:6.2.1.9]
GQA70_23235  malate--CoA ligase subunit beta [KO:K14067] [EC:6.2.1.9]
GQA70_03265  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GQA70_18770  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GQA70_18985  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
GQA70_11770  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GQA70_16355  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GQA70_16360  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
GQA70_03200  (R)-hydratase [KO:K17865] [EC:4.2.1.55]
GQA70_04865  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
GQA70_01515  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
GQA70_04875  protein meaA [KO:K14447] [EC:5.4.99.63]
GQA70_15605  acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
GQA70_04805  hypothetical protein [KO:K14449] [EC:4.2.1.148]
GQA70_23220  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
GQA70_15345  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
GQA70_04790  CoA ester lyase [KO:K14451] [EC:3.1.2.30]
GQA70_11420  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01965] [EC:6.4.1.3]
GQA70_11445  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
GQA70_11395  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GQA70_01080  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
GQA70_01075  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
GQA70_01065  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
GQA70_10825  catalase [KO:K03781] [EC:1.11.1.6]
GQA70_18445  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
GQA70_23435  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
GQA70_14305  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
GQA70_16825  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
GQA70_05075  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
GQA70_05800  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
GQA70_11180  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
GQA70_00120  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
GQA70_07185  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GQA70_12950  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GQA70_12960  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GQA70_14490  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GQA70_02395  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GQA70_20975  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GQA70_23255  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GQA70_19035  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
GQA70_19045  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
GQA70_23210  tdm; trimethylamine-oxide aldolase Tdm [KO:K00605] [EC:2.1.2.10]
GQA70_23290  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
GQA70_01330  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GQA70_21810  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GQA70_12335  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GQA70_15740  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GQA70_19040  gcvH; glycine cleavage system protein GcvH [KO:K02437]
GQA70_21760  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
GQA70_23215  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
GQA70_09410  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
GQA70_23420  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
GQA70_07435  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GQA70_21835  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
GQA70_00670  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
GQA70_02980  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
GQA70_21845  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
GQA70_23190  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
GQA70_23185  NADH-quinone oxidoreductase subunit F [KO:K22515] [EC:1.17.1.9]
GQA70_13340  NADH-quinone oxidoreductase subunit F [KO:K22515] [EC:1.17.1.9]
GQA70_00675  4Fe-4S dicluster domain-containing protein [KO:K00124]
GQA70_21850  formate dehydrogenase [KO:K00124]
GQA70_00680  formate dehydrogenase subunit gamma [KO:K00127]
GQA70_21855  formate dehydrogenase subunit gamma [KO:K00127]
GQA70_18450  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
GQA70_20965  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
GQA70_19950  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
palx00010  Glycolysis / Gluconeogenesis
palx00020  Citrate cycle (TCA cycle)
palx00030  Pentose phosphate pathway
palx00053  Ascorbate and aldarate metabolism
palx00071  Fatty acid degradation
palx00230  Purine metabolism
palx00250  Alanine, aspartate and glutamate metabolism
palx00260  Glycine, serine and threonine metabolism
palx00620  Pyruvate metabolism
palx00710  Carbon fixation by Calvin cycle
palx00750  Vitamin B6 metabolism
palx00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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