KEGG   PATHWAY: pcax00230
Entry
pcax00230                   Pathway                                
Name
Purine metabolism - Pseudomonas carboxydohydrogena
Class
Metabolism; Nucleotide metabolism
Pathway map
pcax00230  Purine metabolism
pcax00230

Module
pcax_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pcax00230]
pcax_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pcax00230]
pcax_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pcax00230]
pcax_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pcax00230]
pcax_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pcax00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas carboxydohydrogena [GN:pcax]
Gene
AFIC_000531  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
AFIC_002739  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
AFIC_001924  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
AFIC_002780  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
AFIC_001888  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
AFIC_001189  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
AFIC_001186  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
AFIC_001188  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
AFIC_001887  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
AFIC_000848  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
AFIC_000849  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
AFIC_001185  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
AFIC_001200  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
AFIC_000234  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
AFIC_002388  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
AFIC_001643  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AFIC_002737  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
AFIC_001952  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
AFIC_001892  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
AFIC_000169  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
AFIC_001249  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
AFIC_001277  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
AFIC_001278  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
AFIC_001279  (2Fe-2S)-binding protein [KO:K13483]
AFIC_001949  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
AFIC_001907  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
AFIC_001855  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
AFIC_002227  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
AFIC_000241  ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
AFIC_001632  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
AFIC_002337  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
AFIC_001469  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
AFIC_001883  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
AFIC_001955  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
AFIC_001719  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
AFIC_002457  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
AFIC_002694  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
AFIC_002830  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
AFIC_001347  adenylate kinase [KO:K00939] [EC:2.7.4.3]
AFIC_001743  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
AFIC_000611  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
AFIC_000612  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
AFIC_002369  gamma-glutamyltransferase family protein [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pcax00030  Pentose phosphate pathway
pcax00220  Arginine biosynthesis
pcax00250  Alanine, aspartate and glutamate metabolism
pcax00260  Glycine, serine and threonine metabolism
pcax00340  Histidine metabolism
pcax00630  Glyoxylate and dicarboxylate metabolism
pcax00730  Thiamine metabolism
pcax00740  Riboflavin metabolism
pcax00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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