KEGG   PATHWAY: pda00053
Entry
pda00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Phoenix dactylifera (date palm)
Class
Metabolism; Carbohydrate metabolism
Pathway map
pda00053  Ascorbate and aldarate metabolism
pda00053

Module
pda_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:pda00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Phoenix dactylifera (date palm) [GN:pda]
Gene
103704461  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
103709251  UDP-glucose 6-dehydrogenase 5 [KO:K00012] [EC:1.1.1.22]
103718180  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
103695952  UDP-glucose 6-dehydrogenase 5 [KO:K00012] [EC:1.1.1.22]
103713110  UDP-sugar pyrophosphorylase [KO:K12447] [EC:2.7.7.64]
103696387  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
103702825  glucuronokinase 1-like isoform X2 [KO:K16190] [EC:2.7.1.43]
103713452  probable inositol oxygenase isoform X2 [KO:K00469] [EC:1.13.99.1]
103718566  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
120107551  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
120112536  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
103716765  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
103716780  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
103714379  aldose reductase-like isoform X1 [KO:K00002] [EC:1.1.1.2]
103714380  aldose reductase isoform X1 [KO:K00002] [EC:1.1.1.2]
103697990  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
103706838  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
103696384  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
103707507  probable L-gulonolactone oxidase 4 [KO:K00103] [EC:1.1.3.8]
103718012  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
103716162  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
103695731  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
103700830  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
103710494  GDP-L-galactose phosphorylase 1-like isoform X1 [KO:K14190] [EC:2.7.7.69]
103711043  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
103717173  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
103717921  GDP-L-galactose phosphorylase 1-like isoform X2 [KO:K14190] [EC:2.7.7.69]
103720528  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
103697686  inositol monophosphatase 3 isoform X1 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
103711558  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
103707620  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
103720720  L-galactono-1,4-lactone dehydrogenase 2, mitochondrial [KO:K00225] [EC:1.3.2.3]
103701187  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
103710462  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
103710561  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
103709399  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
103710614  UDP-glucuronate 4-epimerase 6-like isoform X1 [KO:K08679] [EC:5.1.3.6]
103700226  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
120109412  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
120110904  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
103701999  monodehydroascorbate reductase 2, peroxisomal-like isoform X1 [KO:K08232] [EC:1.6.5.4]
103711527  monodehydroascorbate reductase 2, peroxisomal [KO:K08232] [EC:1.6.5.4]
103715398  monodehydroascorbate reductase 3, cytosolic [KO:K08232] [EC:1.6.5.4]
103715799  monodehydroascorbate reductase 5, chlorplastic isoform X1 [KO:K08232] [EC:1.6.5.4]
103701344  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
103709007  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
103706176  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
103702852  L-ascorbate peroxidase 1, cytosolic [KO:K00434] [EC:1.11.1.11]
103708739  LOW QUALITY PROTEIN: putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
103719946  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
103720470  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
103706644  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
103706622  probable glutathione S-transferase DHAR1, cytosolic isoform X2 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
103710555  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
103719938  probable glutathione S-transferase DHAR2, chloroplastic isoform X1 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
103709578  L-ascorbate oxidase isoform X1 [KO:K00423] [EC:1.10.3.3]
103709696  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
103705900  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
103702183  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
103717889  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
103701342  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
103701633  aldehyde dehydrogenase family 2 member B7, mitochondrial [KO:K00128] [EC:1.2.1.3]
103710071  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
103710055  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
103717123  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
103709342  aldehyde dehydrogenase family 7 member A1 isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
pda00020  Citrate cycle (TCA cycle)
pda00040  Pentose and glucuronate interconversions
pda00051  Fructose and mannose metabolism
pda00520  Amino sugar and nucleotide sugar metabolism
pda00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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