KEGG   PATHWAY: peu00053
Entry
peu00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Populus euphratica (Euphrates poplar)
Class
Metabolism; Carbohydrate metabolism
Pathway map
peu00053  Ascorbate and aldarate metabolism
peu00053

Module
peu_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:peu00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Populus euphratica (Euphrates poplar) [GN:peu]
Gene
105133519  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
105116487  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
105121402  UDP-glucose 6-dehydrogenase 5 [KO:K00012] [EC:1.1.1.22]
105113943  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
105127743  UDP-sugar pyrophosphorylase [KO:K12447] [EC:2.7.7.64]
105109945  glucuronokinase 1 [KO:K16190] [EC:2.7.1.43]
105123266  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
105114144  inositol oxygenase 2 [KO:K00469] [EC:1.13.99.1]
105126235  inositol oxygenase 1 [KO:K00469] [EC:1.13.99.1]
105116690  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
105116692  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
105123673  alcohol dehydrogenase [NADP(+)]-like [KO:K00002] [EC:1.1.1.2]
105115253  LOW QUALITY PROTEIN: 3-oxo-5-beta-steroid 4-dehydrogenase-like [KO:K00002] [EC:1.1.1.2]
105126230  alcohol dehydrogenase [NADP(+)]-like [KO:K00002] [EC:1.1.1.2]
105112384  aldo-keto reductase family 4 member C9-like [KO:K00002] [EC:1.1.1.2]
105119262  alcohol dehydrogenase [NADP(+)]-like [KO:K00002] [EC:1.1.1.2]
105126260  uncharacterized protein LOC105126260 [KO:K00103] [EC:1.1.3.8]
105126261  uncharacterized protein LOC105126261 [KO:K00103] [EC:1.1.3.8]
105127151  L-gulonolactone oxidase [KO:K00103] [EC:1.1.3.8]
105135414  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
105131235  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
105141239  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
105123485  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
105138436  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
105114198  inositol-phosphate phosphatase-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
105136524  inositol monophosphatase 3-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
105120157  bifunctional phosphatase IMPL2, chloroplastic-like [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
105142070  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
105109729  L-galactose dehydrogenase-like [KO:K17744] [EC:1.1.1.316]
105129751  L-galactose dehydrogenase-like [KO:K17744] [EC:1.1.1.316]
105131724  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
105129553  UDP-glucuronate 4-epimerase 2-like [KO:K08679] [EC:5.1.3.6]
105110320  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
105118523  UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
105120800  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
105132379  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
105118597  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
105119760  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
105121236  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
105137922  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
105132241  UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
105115356  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
105111476  probable monodehydroascorbate reductase, cytoplasmic isoform 2 [KO:K08232] [EC:1.6.5.4]
105129106  monodehydroascorbate reductase, chloroplastic [KO:K08232] [EC:1.6.5.4]
105121800  monodehydroascorbate reductase-like [KO:K08232] [EC:1.6.5.4]
105127784  probable L-ascorbate peroxidase 6, chloroplastic isoform X1 [KO:K00434] [EC:1.11.1.11]
105140948  L-ascorbate peroxidase 3, peroxisomal-like [KO:K00434] [EC:1.11.1.11]
105142465  L-ascorbate peroxidase 2, cytosolic [KO:K00434] [EC:1.11.1.11]
105114120  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
105107245  probable L-ascorbate peroxidase 6, chloroplastic isoform X1 [KO:K00434] [EC:1.11.1.11]
105136153  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
105138704  L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
105141227  L-ascorbate peroxidase 3, peroxisomal-like [KO:K00434] [EC:1.11.1.11]
105110717  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
105127481  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
105123341  glutathione S-transferase DHAR2-like isoform X1 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
105123470  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
105126061  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
105138917  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
105142272  L-ascorbate oxidase homolog isoform X1 [KO:K00423] [EC:1.10.3.3]
105142273  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
105112161  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
105127783  aldehyde dehydrogenase family 3 member H1 [KO:K00128] [EC:1.2.1.3]
105139547  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
105139548  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
105109973  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
105128564  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
105112268  aldehyde dehydrogenase family 3 member F1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
105130341  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
105107247  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
105109452  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
105110194  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
105126661  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
105133969  aldehyde dehydrogenase family 7 member B4-like [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
105133435  aldehyde dehydrogenase family 7 member B4 isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
peu00020  Citrate cycle (TCA cycle)
peu00040  Pentose and glucuronate interconversions
peu00051  Fructose and mannose metabolism
peu00520  Amino sugar and nucleotide sugar metabolism
peu00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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