KEGG   PATHWAY: pfr00230
Entry
pfr00230                    Pathway                                
Name
Purine metabolism - Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1
Class
Metabolism; Nucleotide metabolism
Pathway map
pfr00230  Purine metabolism
pfr00230

Module
pfr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pfr00230]
pfr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pfr00230]
pfr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pfr00230]
Other DBs
GO: 0006163 0042278
Organism
Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1 [GN:pfr]
Gene
PFREUD_10610  pgm1; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
PFREUD_17400  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
PFREUD_22260  ribose-phosphate pyrophosphokinase (RPPK) (Phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase) [KO:K00948] [EC:2.7.6.1]
PFREUD_04770  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
PFREUD_04000  purD; Phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
PFREUD_06820  purN; 5-phosphoribosylglycinamide formyltransferase (phosphoribosylglycinamide formyltransferase) [KO:K11175] [EC:2.1.2.2]
PFREUD_04680  purL; Phosphoribosylformylglycinamidine synthase II (FGAM synthase II) [KO:K23269] [EC:6.3.5.3]
PFREUD_04040  purS; Phosphoribosylformylglycinamidine synthetase PurS [KO:K23264] [EC:6.3.5.3]
PFREUD_04050  purL_purQ; Phosphoribosylformylglycinamidine synthase 1 (Phosphoribosylformylglycinamidine synthase I) (FGAM synthase I) [KO:K23265] [EC:6.3.5.3 3.5.1.2]
PFREUD_04780  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
PFREUD_07300  purK; Phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
PFREUD_07310  purE; Phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
PFREUD_04010  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
PFREUD_06830  purH; Phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) [KO:K00602] [EC:2.1.2.3 3.5.4.10]
PFREUD_11660  apt; Adenine phosphoribosyltransferase (AMP:diphosphate phospho-D-ribosyltransferase) [KO:K00759] [EC:2.4.2.7]
PFREUD_15460  Hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
PFREUD_19310  iunH; Inosine/uridine-preferring nucleoside hydrolase (purine nucleosidase) [KO:K01239] [EC:3.2.2.1]
PFREUD_20330  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
PFREUD_06480  guaB1; Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase) [KO:K00088] [EC:1.1.1.205]
PFREUD_06490  guaB2; Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase [KO:K00088] [EC:1.1.1.205]
PFREUD_08360  ndk; Nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
PFREUD_07600  HAM1, NTPase/HAM1 [KO:K01519] [EC:3.6.1.66]
PFREUD_06680  guaA; GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase) [KO:K01951] [EC:6.3.5.2]
PFREUD_22250  guA; Glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
PFREUD_15850  guaB3; Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase [KO:K26110] [EC:1.7.1.7]
PFREUD_11430  gmk; Guanylate kinase, Guanosine monophosphate kinase (GMP kinase) [KO:K00942] [EC:2.7.4.8]
PFREUD_13010  nrdJ; Vitamin B12-dependent ribonucleotide reductase (Ribonucleoside-diphosphate reductase NrdJ) [KO:K00525] [EC:1.17.4.1]
PFREUD_09280  dgt; Deoxyguanosinetriphosphate triphosphohydrolase (dGTPase) [KO:K01129] [EC:3.1.5.1]
PFREUD_11650  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
PFREUD_17290  ppx; Ppx/GppA phosphatase family [KO:K01524] [EC:3.6.1.11 3.6.1.40]
PFREUD_19280  purA; Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase) [KO:K01939] [EC:6.3.4.4]
PFREUD_04380  add; Adenosine deaminase (Adenosine aminohydrolase) [KO:K01488] [EC:3.5.4.4]
PFREUD_05980  adk; Adenylate kinase (EC 2.7.4.3) (ATP-AMP transphosphorylase) [KO:K00939] [EC:2.7.4.3]
PFREUD_08780  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
PFREUD_12430  HIT family protein [KO:K19710] [EC:2.7.7.53]
PFREUD_21650  cysN; Sulfate adenylyltransferase, large subunit/ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase) [KO:K00956] [EC:2.7.7.4]
PFREUD_21640  mmcV_cysD; Sulfate adenylyltransferase subunit 2 (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase small subunit) (Mitomycin biosynthesis protein V) [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pfr00030  Pentose phosphate pathway
pfr00220  Arginine biosynthesis
pfr00250  Alanine, aspartate and glutamate metabolism
pfr00260  Glycine, serine and threonine metabolism
pfr00340  Histidine metabolism
pfr00630  Glyoxylate and dicarboxylate metabolism
pfr00730  Thiamine metabolism
pfr00740  Riboflavin metabolism
pfr00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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