KEGG   PATHWAY: pkc00630
Entry
pkc00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas knackmussii
Class
Metabolism; Carbohydrate metabolism
Pathway map
pkc00630  Glyoxylate and dicarboxylate metabolism
pkc00630

Module
pkc_M00621  Glycine cleavage system [PATH:pkc00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas knackmussii [GN:pkc]
Gene
PKB_3392  Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
PKB_4231  acsA; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
PKB_1583  acsA1; Acetyl-coenzyme A synthetase 1 [KO:K01895] [EC:6.2.1.1]
PKB_3135  putative AMP-binding protein [KO:K01895] [EC:6.2.1.1]
PKB_4953  acsA2; Acetyl-coenzyme A synthetase 2 [KO:K01895] [EC:6.2.1.1]
PKB_0496  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
PKB_2037  gltA; Citrate synthase [KO:K01647] [EC:2.3.3.1]
PKB_4870  prpC; 2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
PKB_2162  acna1; Aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
PKB_1971  acnB; Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
PKB_4245  fada9; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
PKB_4258  paaj3; 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoAthiolase [KO:K00626] [EC:2.3.1.9]
PKB_1919  fada1; Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
PKB_3133  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PKB_4955  atob3; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PKB_2842  atob1; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PKB_5110  fadI; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
PKB_4386  catF; Beta-ketoadipyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
PKB_4656  thlA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PKB_1522  phaJ1; (R)-specific enoyl-CoA hydratase [KO:K17865] [EC:4.2.1.55]
PKB_5685  glcD; Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
PKB_5684  glcE; Glycolate oxidase subunit glcE [KO:K11472] [EC:1.1.99.14]
PKB_5683  glcF; Glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
PKB_2400  catalase [KO:K03781] [EC:1.11.1.6]
PKB_2707  catalase [KO:K03781] [EC:1.11.1.6]
PKB_0945  ghrB; Glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
PKB_4660  hprA; glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
PKB_0560  gph1; Phosphoglycolate phosphatase 1 [KO:K01091] [EC:3.1.3.18]
PKB_3745  putative hydrolase [KO:K01091] [EC:3.1.3.18]
PKB_0090  5'-nucleotidase [KO:K01091] [EC:3.1.3.18]
PKB_1628  hypothetical protein [KO:K01915] [EC:6.3.1.2]
PKB_0131  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PKB_0142  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PKB_0520  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PKB_2193  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PKB_2320  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PKB_5411  glnA; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PKB_5594  spuB; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PKB_5596  puuA; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
PKB_0188  glyA1; Serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
PKB_2331  glyA1; Serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
PKB_4823  glyA2; Serine hydroxymethyltransferase 3 [KO:K00600] [EC:2.1.2.1]
PKB_1348  gcvP1; Glycine dehydrogenase [decarboxylating] 1 [KO:K00281] [EC:1.4.4.2]
PKB_0358  gcvP2; Glycine dehydrogenase [decarboxylating] 2 [KO:K00281] [EC:1.4.4.2]
PKB_2332  gcvP1; Glycine dehydrogenase [decarboxylating] 1 [KO:K00281] [EC:1.4.4.2]
PKB_1349  gcvt3; Aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
PKB_0356  gcvt1; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
PKB_2329  gcvt5; Aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
PKB_2044  lpdG; Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
PKB_3488  lpd3; Dihydrolipoyl dehydrogenase 3 [KO:K00382] [EC:1.8.1.4]
PKB_2851  lpdV; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
PKB_1347  Conserved hypothetical protein [KO:K02437]
PKB_0357  gcvH2; Glycine cleavage system H protein 2 [KO:K02437]
PKB_2333  Conserved hypothetical protein [KO:K02437]
PKB_5121  hypothetical protein [KO:K02437]
PKB_1792  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
PKB_1791  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
PKB_1514  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
PKB_1790  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
PKB_1481  glxK; Glycerate kinase [KO:K00865] [EC:2.7.1.165]
PKB_1789  ttuD; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
PKB_3916  eda; 2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
PKB_2393  hypothetical protein [KO:K00126] [EC:1.17.1.9]
PKB_2394  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
PKB_5138  fdog1; Formate dehydrogenase-O major subunit [KO:K00123] [EC:1.17.1.9]
PKB_5139  fdog3; Formate dehydrogenase-O major subunit [KO:K00123] [EC:1.17.1.9]
PKB_2395  NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [KO:K00124]
PKB_5137  fdoH; Formate dehydrogenase-O iron-sulfur subunit [KO:K00124]
PKB_2396  fdsG; formate dehydrogenase, gamma subunit [KO:K00127]
PKB_5136  fdoI; Formate dehydrogenase, cytochrome(fdo) subunit [KO:K00127]
PKB_3255  Conserved hypothetical protein [KO:K01432] [EC:3.5.1.9]
PKB_3603  Conserved hypothetical protein [KO:K01432] [EC:3.5.1.9]
PKB_0183  puru1; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
PKB_4688  puru3; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
PKB_5389  hutG; N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pkc00010  Glycolysis / Gluconeogenesis
pkc00020  Citrate cycle (TCA cycle)
pkc00030  Pentose phosphate pathway
pkc00053  Ascorbate and aldarate metabolism
pkc00071  Fatty acid degradation
pkc00230  Purine metabolism
pkc00250  Alanine, aspartate and glutamate metabolism
pkc00260  Glycine, serine and threonine metabolism
pkc00620  Pyruvate metabolism
pkc00710  Carbon fixation by Calvin cycle
pkc00750  Vitamin B6 metabolism
pkc00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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