KEGG   PATHWAY: ppug00330
Entry
ppug00330                   Pathway                                
Name
Arginine and proline metabolism - Pungitius pungitius (ninespine stickleback)
Class
Metabolism; Amino acid metabolism
Pathway map
ppug00330  Arginine and proline metabolism
ppug00330

Module
ppug_M00015  Proline biosynthesis, glutamate => proline [PATH:ppug00330]
ppug_M00047  Creatine pathway [PATH:ppug00330]
ppug_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:ppug00330]
ppug_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:ppug00330]
ppug_M00970  Proline degradation, proline => glutamate [PATH:ppug00330]
ppug_M00972  Proline metabolism [PATH:ppug00330]
Other DBs
GO: 0006525 0006560
Organism
Pungitius pungitius (ninespine stickleback) [GN:ppug]
Gene
119225866  gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
119216832  gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
119226393  ckmt2a; creatine kinase, mitochondrial 2a (sarcomeric) isoform X1 [KO:K00933] [EC:2.7.3.2]
119227844  ckba; creatine kinase, brain a [KO:K00933] [EC:2.7.3.2]
119194705  ckbb; creatine kinase, brain b [KO:K00933] [EC:2.7.3.2]
119196373  creatine kinase U-type, mitochondrial-like [KO:K00933] [EC:2.7.3.2]
119225682  creatine kinase U-type, mitochondrial-like [KO:K00933] [EC:2.7.3.2]
119215752  ckmb; creatine kinase, muscle b isoform X1 [KO:K27382] [EC:2.7.3.2]
119215190  ckma; creatine kinase, muscle a [KO:K27382] [EC:2.7.3.2]
119217638  zgc:172076 [KO:K27382] [EC:2.7.3.2]
119220263  ornithine decarboxylase-like [KO:K01581] [EC:4.1.1.17]
119227742  odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
119223428  srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
119215611  sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
119195204  amd1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
119198447  aoc1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
119218349  smox; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
119220989  aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
119215523  aldh3a2b; aldehyde dehydrogenase family 3 member A2b [KO:K00128] [EC:1.2.1.3]
119221571  aldehyde dehydrogenase, dimeric NADP-preferring-like [KO:K00128] [EC:1.2.1.3]
119218555  aldehyde dehydrogenase family 3 member A2-like [KO:K00128] [EC:1.2.1.3]
119197682  aldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
119216332  aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
119209085  aldh9a1b; 4-trimethylaminobutyraldehyde dehydrogenase B [KO:K00149] [EC:1.2.1.47 1.2.1.3]
119216616  aldh9a1a.1; 4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
119219246  cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
119198997  diamine acetyltransferase 1-like [KO:K00657] [EC:2.3.1.57]
119215810  sat2b; diamine acetyltransferase 2b [KO:K00657] [EC:2.3.1.57]
119223218  thialysine N-epsilon-acetyltransferase-like [KO:K00657] [EC:2.3.1.57]
119229068  mao; amine oxidase [flavin-containing] [KO:K00274] [EC:1.4.3.4]
119226222  si:ch211-127i16.2; probable flavin-containing monoamine oxidase A isoform X1 [KO:K00274] [EC:1.4.3.4]
119223359  agmat; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
119225179  nos1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
119227527  arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
119212461  arg1; arginase-1 [KO:K01476] [EC:3.5.3.1]
119212517  oat; ornithine aminotransferase, mitochondrial isoform X1 [KO:K00819] [EC:2.6.1.13]
119220347  pyrroline-5-carboxylate reductase 1, mitochondrial-like isoform X1 [KO:K00286] [EC:1.5.1.2]
119217264  pycr3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
119218156  pycr1b; pyrroline-5-carboxylate reductase 1b [KO:K00286] [EC:1.5.1.2]
119226700  prodha; proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
119229444  aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
119214436  delta-1-pyrroline-5-carboxylate synthase-like [KO:K12657] [EC:2.7.2.11 1.2.1.41]
119213008  aldh18a1; delta-1-pyrroline-5-carboxylate synthase [KO:K12657] [EC:2.7.2.11 1.2.1.41]
119218572  lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
119214295  p4ha1b; prolyl 4-hydroxylase subunit alpha-1b isoform X1 [KO:K00472] [EC:1.14.11.2]
119215724  p4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
119218944  p4ha3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
119212632  prodh2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
119214194  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
119224573  got1l1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
119218019  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
119229772  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
119218010  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
119224724  D-amino-acid oxidase-like [KO:K00273] [EC:1.4.3.3]
119195400  trans-L-3-hydroxyproline dehydratase [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
ppug00020  Citrate cycle (TCA cycle)
ppug00220  Arginine biosynthesis
ppug00250  Alanine, aspartate and glutamate metabolism
ppug00260  Glycine, serine and threonine metabolism
ppug00270  Cysteine and methionine metabolism
ppug00310  Lysine degradation
ppug00410  beta-Alanine metabolism
ppug00470  D-Amino acid metabolism
ppug00480  Glutathione metabolism
ppug00630  Glyoxylate and dicarboxylate metabolism
ppug00650  Butanoate metabolism
ppug00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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