KEGG   PATHWAY: ppx00630
Entry
ppx00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas putida DOT-T1E
Class
Metabolism; Carbohydrate metabolism
Pathway map
ppx00630  Glyoxylate and dicarboxylate metabolism
ppx00630

Module
ppx_M00012  Glyoxylate cycle [PATH:ppx00630]
ppx_M00621  Glycine cleavage system [PATH:ppx00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas putida DOT-T1E [GN:ppx]
Gene
T1E_5014  aceA; Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
T1E_0550  acsA; AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
T1E_0628  acsB; Acetyl-coenzyme A synthetase 2 [KO:K01895] [EC:6.2.1.1]
T1E_4053  Acetyl-coenzyme A synthetase 1 [KO:K01895] [EC:6.2.1.1]
T1E_2197  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
T1E_0782  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
T1E_0434  gltA; Citrate synthase [KO:K01647] [EC:2.3.3.1]
T1E_5347  prpC; methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
T1E_5164  acnA; Aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
T1E_5343  acnB; Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
T1E_0548  thio; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
T1E_0149  thlA; beta-ketothiolase [KO:K00626] [EC:2.3.1.9]
T1E_3753  fadI; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
T1E_3602  pkt3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
T1E_3097  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
T1E_0140  glcD; Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
T1E_0141  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
T1E_0142  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
T1E_4765  catC; Catalase HPII [KO:K03781] [EC:1.11.1.6]
T1E_1657  srpA; catalase domain-containing protein [KO:K03781] [EC:1.11.1.6]
T1E_3479  Catalase [KO:K03781] [EC:1.11.1.6]
T1E_1575  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
T1E_0952  hprA; glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
T1E_2137  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
T1E_0919  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
T1E_1286  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
T1E_0178  glnA; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
T1E_4443  glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
T1E_4444  glutamine synthetase, putative [KO:K01915] [EC:6.3.1.2]
T1E_0852  puuA; glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
T1E_1075  glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
T1E_2050  glnT; glutamine synthetase, type III [KO:K01915] [EC:6.3.1.2]
T1E_1260  glutamine synthetase, putative [KO:K01915] [EC:6.3.1.2]
T1E_4014  glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
T1E_5097  glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
T1E_0766  glyA; Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
T1E_3549  glyA-1; Serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
T1E_5528  Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
T1E_4435  gcvP-2; Glycine dehydrogenase [decarboxylating] 2 [KO:K00281] [EC:1.4.4.2]
T1E_1964  gcvP-1; Glycine dehydrogenase [decarboxylating] 1 [KO:K00281] [EC:1.4.4.2]
T1E_4433  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
T1E_1962  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
T1E_0427  lpdG; Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
T1E_3946  lpd3; Dihydrolipoyl dehydrogenase 3 [KO:K00382] [EC:1.8.1.4]
T1E_5102  lpdV; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
T1E_4434  Glycine cleavage system H protein 2 [KO:K02437]
T1E_1965  gcvH; Glycine cleavage system H protein 1 [KO:K02437]
T1E_3071  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
T1E_3072  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
T1E_3073  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
T1E_1046  glxK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
T1E_3075  ttuD; hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
T1E_1253  ttdA; tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
T1E_1252  ttdB; L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
T1E_2001  keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
T1E_1269  formate dehydrogenase, delta subunit, putative [KO:K00126] [EC:1.17.1.9]
T1E_3488  fdoG; molybdopterin oxidoreductase Fe4S4 region [KO:K00123] [EC:1.17.1.9]
T1E_3489  Formate dehydrogenase-O major subunit [KO:K00123] [EC:1.17.1.9]
T1E_1268  yjgC; formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
T1E_1267  nuoF2; NADH dehydrogenase [KO:K00124]
T1E_3490  fdoH; formate dehydrogenase, beta subunit [KO:K00124]
T1E_1266  formate dehydrogenase subunit gamma [KO:K00127]
T1E_3491  fdoI; formate dehydrogenase, gamma subunit [KO:K00127]
T1E_0221  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
T1E_2048  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
T1E_3544  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
T1E_2484  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ppx00010  Glycolysis / Gluconeogenesis
ppx00020  Citrate cycle (TCA cycle)
ppx00030  Pentose phosphate pathway
ppx00053  Ascorbate and aldarate metabolism
ppx00071  Fatty acid degradation
ppx00230  Purine metabolism
ppx00250  Alanine, aspartate and glutamate metabolism
ppx00260  Glycine, serine and threonine metabolism
ppx00620  Pyruvate metabolism
ppx00710  Carbon fixation by Calvin cycle
ppx00750  Vitamin B6 metabolism
ppx00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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