KEGG   PATHWAY: psat00053
Entry
psat00053                   Pathway                                
Name
Ascorbate and aldarate metabolism - Pisum sativum (pea)
Class
Metabolism; Carbohydrate metabolism
Pathway map
psat00053  Ascorbate and aldarate metabolism
psat00053

Module
psat_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:psat00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Pisum sativum (pea) [GN:psat]
Gene
127073744  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
127119642  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
127081129  uncharacterized protein LOC127081129 [KO:K00012] [EC:1.1.1.22]
127128613  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
127082747  UDP-sugar pyrophospharylase [KO:K12447] [EC:2.7.7.64]
127118915  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
127108399  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
127076450  inositol oxygenase 1-like isoform X1 [KO:K00469] [EC:1.13.99.1]
127091984  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127074891  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127074892  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127122359  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127100515  LOW QUALITY PROTEIN: NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127101009  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
127101010  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127101012  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127101918  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127127576  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
127103422  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127129212  aldose reductase [KO:K00002] [EC:1.1.1.2]
127105400  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127136688  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
127076131  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
127129437  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
127132180  L-gulonolactone oxidase 5-like [KO:K00103] [EC:1.1.3.8]
127091812  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
127132236  GDP-mannose 3,5-epimerase 2 isoform X1 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
127117675  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
127084878  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
127076822  inositol-phosphate phosphatase [KO:K10047] [EC:3.1.3.25 3.1.3.93]
127083375  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
127108282  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
127098460  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
127074107  UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
127120660  UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
127127974  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
127083184  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
127107547  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
127138483  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
127092723  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
127100829  monodehydroascorbate reductase, chloroplastic/mitochondrial [KO:K08232] [EC:1.6.5.4]
127128010  monodehydroascorbate reductase 4, peroxisomal isoform X1 [KO:K08232] [EC:1.6.5.4]
127087660  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
127120134  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
127082822  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
127105270  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
127107321  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
127098111  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
127126936  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
127083802  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
127083234  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
127083556  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
127107702  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
127107703  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
127087220  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
127113365  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
127087516  betaine aldehyde dehydrogenase, chloroplastic-like [KO:K00128] [EC:1.2.1.3]
127118315  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
127073904  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
127092318  aldehyde dehydrogenase family 3 member H1 isoform X1 [KO:K00128] [EC:1.2.1.3]
127074638  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
127093277  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
127075101  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
127075102  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
127122061  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
127080002  betaine aldehyde dehydrogenase, chloroplastic-like [KO:K00128] [EC:1.2.1.3]
127082829  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
127102697  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
127105093  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
127130575  uncharacterized protein LOC127130575 [KO:K00128] [EC:1.2.1.3]
127106799  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
127107376  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
127136968  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
127108262  uncharacterized protein LOC127108262 [KO:K00128] [EC:1.2.1.3]
127135842  aldehyde dehydrogenase family 7 member A1 isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
psat00020  Citrate cycle (TCA cycle)
psat00040  Pentose and glucuronate interconversions
psat00051  Fructose and mannose metabolism
psat00520  Amino sugar and nucleotide sugar metabolism
psat00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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