KEGG   PATHWAY: pset00310
Entry
pset00310                   Pathway                                
Name
Lysine degradation - Pseudomonas sp. TCU-HL1
Class
Metabolism; Amino acid metabolism
Pathway map
pset00310  Lysine degradation
pset00310

Module
pset_M00957  Lysine degradation, bacteria, L-lysine => glutarate => succinate/acetyl-CoA [PATH:pset00310]
pset_M00960  Lysine degradation, bacteria, L-lysine => D-lysine => succinate [PATH:pset00310]
Other DBs
GO: 0006554
Organism
Pseudomonas sp. TCU-HL1 [GN:pset]
Gene
THL1_2745  L-pipecolate dehydrogenase [KO:K26061]
THL1_5180  aldehyde dehydrogenase [KO:K26061]
THL1_2743  4-aminobutyrate aminotransferase [KO:K26062] [EC:2.6.1.39]
THL1_2178  2-oxoglutarate dehydrogenase E2 component [KO:K00658] [EC:2.3.1.61]
THL1_2179  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
THL1_2431  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
THL1_110  glutaryl-CoA dehydrogenase [KO:K00252] [EC:1.3.8.6]
THL1_3529  glutaryl-CoA dehydrogenase [KO:K00252] [EC:1.3.8.6]
THL1_3186  2,3-dehydroadipyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
THL1_2288  enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
THL1_4237  enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
THL1_3537  enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
THL1_3165  enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
THL1_2125  multifunctional fatty acid oxidation complex subunit alpha [KO:K01825] [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
THL1_2276  3-hydroxyacyl-CoA dehydrogenase [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
THL1_4219  3-hydroxyacyl-CoA dehydrogenase [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
THL1_5072  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
THL1_4177  beta-ketothiolase [KO:K00626] [EC:2.3.1.9]
THL1_3167  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
THL1_1418  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
THL1_1428  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
THL1_2275  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
THL1_3229  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
THL1_3486  beta-ketothiolase [KO:K00626] [EC:2.3.1.9]
THL1_4220  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
THL1_4239  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
THL1_4793  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
THL1_442  amine oxidase [KO:K00468] [EC:1.13.12.2]
THL1_441  carbon-nitrogen hydrolase [KO:K01506] [EC:3.5.1.30]
THL1_5288  racemase [KO:K25316] [EC:5.1.1.10]
THL1_2972  alanine racemase [KO:K25317] [EC:5.1.1.10]
THL1_4632  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
THL1_4637  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
THL1_1957  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
THL1_2262  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
THL1_564  5-aminovalerate aminotransferase [KO:K14268] [EC:2.6.1.48 2.6.1.19]
THL1_118  4-aminobutyrate aminotransferase [KO:K14268] [EC:2.6.1.48 2.6.1.19]
THL1_1566  3-amino-2-methylpropionate transaminase [KO:K14268] [EC:2.6.1.48 2.6.1.19]
THL1_563  succinate-semialdehyde dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
THL1_117  succinate-semialdehyde dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
THL1_1565  succinate-semialdehyde dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
THL1_561  protein CsiD [KO:K15737] [EC:1.14.11.64]
THL1_1563  protein CsiD [KO:K15737] [EC:1.14.11.64]
THL1_562  hydroxyglutarate oxidase [KO:K15736] [EC:1.1.5.13]
THL1_1564  hydroxyglutarate oxidase [KO:K15736] [EC:1.1.5.13]
THL1_2740  hypothetical protein [KO:K25986] [EC:1.13.11.93]
THL1_2742  glycolate dehydrogenase [KO:K26063] [EC:1.1.-.-]
THL1_111  CoA-transferase [KO:K01041] [EC:2.8.3.-]
THL1_215  amino acid dehydrogenase [KO:K26064]
THL1_210  lactate dehydrogenase [KO:K13609] [EC:1.5.1.21]
THL1_3349  oxidoreductase [KO:K13609] [EC:1.5.1.21]
THL1_5179  FAD-dependent oxidoreductase [KO:K26065]
THL1_2746  FAD-dependent oxidoreductase [KO:K26065]
THL1_4224  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
THL1_3996  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
Compound
C00024  Acetyl-CoA
C00026  2-Oxoglutarate
C00037  Glycine
C00042  Succinate
C00047  L-Lysine
C00068  Thiamin diphosphate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00322  2-Oxoadipate
C00332  Acetoacetyl-CoA
C00408  L-Pipecolate
C00431  5-Aminopentanoate
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00450  (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
C00487  Carnitine
C00489  Glutarate
C00527  Glutaryl-CoA
C00739  D-Lysine
C00877  Crotonoyl-CoA
C00956  L-2-Aminoadipate
C00990  5-Aminopentanamide
C01087  (R)-2-Hydroxyglutarate
C01142  (3S)-3,6-Diaminohexanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01149  4-Trimethylammoniobutanal
C01181  4-Trimethylammoniobutanoate
C01186  (3S,5S)-3,5-Diaminohexanoate
C01211  Procollagen 5-hydroxy-L-lysine
C01259  (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
C01672  Cadaverine
C02188  Protein lysine
C02727  N6-Acetyl-L-lysine
C03087  5-Acetamidopentanoate
C03196  (S)-2-Hydroxyglutarate
C03239  6-Amino-2-oxohexanoate
C03273  5-Oxopentanoate
C03366  5-Phosphooxy-L-lysine
C03656  (S)-5-Amino-3-oxohexanoic acid
C03793  N6,N6,N6-Trimethyl-L-lysine
C04020  D-Lysopine
C04076  L-2-Aminoadipate 6-semialdehyde
C04092  Delta1-Piperideine-2-carboxylate
C04487  5-(D-Galactosyloxy)-L-lysine-procollagen
C05161  (2R,5S)-2,5-Diaminohexanoate
C05231  L-3-Aminobutyryl-CoA
C05544  Protein N6-methyl-L-lysine
C05545  Protein N6,N6-dimethyl-L-lysine
C05546  Protein N6,N6,N6-trimethyl-L-lysine
C05548  6-Acetamido-2-oxohexanoate
C05825  2-Amino-5-oxohexanoate
C06157  [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
C12455  5-Aminopentanal
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16741  L-Hydroxylysine
C22667  4-Carboxy-1-hydroxybutyryl-ThPP
Reference
PMID:11802770
  Authors
Vaz FM, Wanders RJ.
  Title
Carnitine biosynthesis in mammals.
  Journal
Biochem J 361:417-29 (2002)
DOI:10.1042/bj3610417
Reference
PMID:1682209
  Authors
Large PJ, Robertson A.
  Title
The route of lysine breakdown in Candida tropicalis.
  Journal
FEMS Microbiol Lett 66:209-13 (1991)
DOI:10.1111/j.1574-6968.1990.tb03998.x
Related
pathway
pset00020  Citrate cycle (TCA cycle)
pset00300  Lysine biosynthesis
pset00311  Penicillin and cephalosporin biosynthesis
pset00780  Biotin metabolism
KO pathway
ko00310   
LinkDB

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