KEGG   PATHWAY: pvy00053
Entry
pvy00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Pistacia vera (pistachio)
Class
Metabolism; Carbohydrate metabolism
Pathway map
pvy00053  Ascorbate and aldarate metabolism
pvy00053

Module
pvy_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:pvy00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Pistacia vera (pistachio) [GN:pvy]
Gene
116115621  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
116116788  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
116124753  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
116127859  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
116140087  UDP-sugar pyrophosphorylase-like [KO:K12447] [EC:2.7.7.64]
116116047  UDP-sugar pyrophosphorylase-like [KO:K12447] [EC:2.7.7.64]
116118346  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
116116069  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
116121261  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
116121267  inositol oxygenase 2-like [KO:K00469] [EC:1.13.99.1]
116112925  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
116113107  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
116139026  inositol oxygenase 1-like isoform X1 [KO:K00469] [EC:1.13.99.1]
116143432  LOW QUALITY PROTEIN: aldose reductase [KO:K00002] [EC:1.1.1.2]
116114970  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
116114971  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
116114984  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
116114986  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
116114987  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
116114988  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
116111971  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
116113983  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
116114638  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
116109016  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
116131114  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
116127273  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
116140860  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
116145226  GDP-L-galactose phosphorylase 2 [KO:K14190] [EC:2.7.7.69]
116117924  LOW QUALITY PROTEIN: GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
116107393  GDP-L-galactose phosphorylase 2-like isoform X1 [KO:K14190] [EC:2.7.7.69]
116115806  inositol-phosphate phosphatase [KO:K10047] [EC:3.1.3.25 3.1.3.93]
116110131  LOW QUALITY PROTEIN: bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
116135288  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
116145983  L-galactono-1,4-lactone dehydrogenase, mitochondrial-like [KO:K00225] [EC:1.3.2.3]
116132103  L-galactono-1,4-lactone dehydrogenase, mitochondrial-like [KO:K00225] [EC:1.3.2.3]
116143757  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
116117205  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
116124301  UDP-glucuronate 4-epimerase 2-like isoform X1 [KO:K08679] [EC:5.1.3.6]
116112229  UDP-glucuronate 4-epimerase 2-like [KO:K08679] [EC:5.1.3.6]
116128194  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
116134133  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
116136395  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
116136397  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
116136398  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
116136399  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
116136400  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
116131868  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
116131869  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
116119683  monodehydroascorbate reductase, seedling isozyme-like [KO:K08232] [EC:1.6.5.4]
116122994  monodehydroascorbate reductase 4, peroxisomal-like [KO:K08232] [EC:1.6.5.4]
116123711  monodehydroascorbate reductase 4, peroxisomal-like [KO:K08232] [EC:1.6.5.4]
116107428  monodehydroascorbate reductase, chloroplastic/mitochondrial [KO:K08232] [EC:1.6.5.4]
116107508  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
116138091  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
116145613  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
116131607  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
116124157  L-ascorbate peroxidase 3 isoform X1 [KO:K00434] [EC:1.11.1.11]
116126833  L-ascorbate peroxidase 2, cytosolic [KO:K00434] [EC:1.11.1.11]
116129839  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
116129862  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
116115920  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
116126915  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
116142154  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
116122674  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
116135665  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
116131598  aldehyde dehydrogenase family 3 member H1 isoform X1 [KO:K00128] [EC:1.2.1.3]
116118005  aldehyde dehydrogenase family 3 member H1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
116118956  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
116121347  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
116122879  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
116112922  aldehyde dehydrogenase family 3 member I1, chloroplastic-like [KO:K00128] [EC:1.2.1.3]
116120273  aldehyde dehydrogenase family 7 member B4 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
pvy00020  Citrate cycle (TCA cycle)
pvy00040  Pentose and glucuronate interconversions
pvy00051  Fructose and mannose metabolism
pvy00520  Amino sugar and nucleotide sugar metabolism
pvy00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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