KEGG   PATHWAY: sanu00230
Entry
sanu00230                   Pathway                                
Name
Purine metabolism - Streptomyces angustmyceticus
Class
Metabolism; Nucleotide metabolism
Pathway map
sanu00230  Purine metabolism
sanu00230

Module
sanu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sanu00230]
sanu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sanu00230]
sanu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sanu00230]
sanu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sanu00230]
sanu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sanu00230]
sanu_M00546  Purine degradation, xanthine => urea [PATH:sanu00230]
sanu_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sanu00230]
sanu_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:sanu00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces angustmyceticus [GN:sanu]
Gene
K7396_21705  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
K7396_00320  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
K7396_19200  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
K7396_19110  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
K7396_14220  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
K7396_19180  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
K7396_19170  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
K7396_19175  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
K7396_19205  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
K7396_22070  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
K7396_22075  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
K7396_19125  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
K7396_02340  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
K7396_14215  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
K7396_29510  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
K7396_00330  hypothetical protein [KO:K00759] [EC:2.4.2.7]
K7396_15235  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
K7396_29215  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
K7396_23020  HAD-IIA family hydrolase [KO:K02566] [EC:3.1.3.5]
K7396_13600  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
K7396_26540  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
K7396_04105  nucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
K7396_15885  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
K7396_20530  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
K7396_20535  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
K7396_23965  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
K7396_22845  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
K7396_00800  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
K7396_01345  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
K7396_04730  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
K7396_00795  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
K7396_01350  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
K7396_04735  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
K7396_00790  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
K7396_01355  (2Fe-2S)-binding protein [KO:K13483]
K7396_14375  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
K7396_29745  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
K7396_30485  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
K7396_29685  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
K7396_09455  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
K7396_12125  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
K7396_12130  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
K7396_11110  dgt; dNTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
K7396_24720  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
K7396_09510  HD domain-containing protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
K7396_29515  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
K7396_15620  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
K7396_21820  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
K7396_13510  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
K7396_19020  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
K7396_26165  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
K7396_13695  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
K7396_20125  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
K7396_24710  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
K7396_26930  5'-nucleotidase C-terminal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
K7396_20320  adenylate kinase [KO:K00939] [EC:2.7.4.3]
K7396_29420  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
K7396_08245  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
K7396_33630  adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
K7396_08255  50S ribosome-binding GTPase [KO:K00956] [EC:2.7.7.4]
K7396_08250  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
K7396_07820  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
K7396_07825  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
K7396_07830  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
K7396_13855  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
K7396_07760  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
K7396_23805  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
K7396_10660  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
K7396_02180  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
K7396_02185  urease subunit beta [KO:K01429] [EC:3.5.1.5]
K7396_02190  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
K7396_10665  ureA; urease subunit gamma [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sanu00030  Pentose phosphate pathway
sanu00220  Arginine biosynthesis
sanu00250  Alanine, aspartate and glutamate metabolism
sanu00260  Glycine, serine and threonine metabolism
sanu00340  Histidine metabolism
sanu00630  Glyoxylate and dicarboxylate metabolism
sanu00730  Thiamine metabolism
sanu00740  Riboflavin metabolism
sanu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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