KEGG   PATHWAY: sdd00230
Entry
sdd00230                    Pathway                                
Name
Purine metabolism - Streptomyces dangxiongensis
Class
Metabolism; Nucleotide metabolism
Pathway map
sdd00230  Purine metabolism
sdd00230

Module
sdd_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sdd00230]
sdd_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sdd00230]
sdd_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sdd00230]
sdd_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sdd00230]
sdd_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sdd00230]
sdd_M00546  Purine degradation, xanthine => urea [PATH:sdd00230]
sdd_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sdd00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces dangxiongensis [GN:sdd]
Gene
D9753_33670  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
D9753_20835  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
D9753_18565  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
D9753_18470  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
D9753_13830  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
D9753_18545  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
D9753_18535  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
D9753_18540  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
D9753_18570  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
D9753_21205  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
D9753_21210  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
D9753_18490  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
D9753_30620  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
D9753_13825  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
D9753_29365  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
D9753_19005  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
D9753_22200  HAD family hydrolase [KO:K02566] [EC:3.1.3.5]
D9753_13285  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
D9753_26295  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D9753_15630  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
D9753_14025  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
D9753_14030  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
D9753_15910  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
D9753_23645  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
D9753_22050  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
D9753_04300  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
D9753_34705  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
D9753_04305  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
D9753_34700  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
D9753_04310  oxidoreductase [KO:K13483]
D9753_34695  (2Fe-2S)-binding protein [KO:K13483]
D9753_13970  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
D9753_29595  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
D9753_29535  guanylate kinase [KO:K00942] [EC:2.7.4.8]
D9753_09035  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
D9753_11925  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
D9753_11930  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
D9753_24315  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
D9753_09155  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
D9753_15395  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
D9753_20985  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
D9753_02220  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
D9753_13230  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
D9753_16515  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
D9753_15825  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
D9753_25920  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
D9753_13360  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
D9753_14480  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
D9753_33035  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
D9753_23970  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
D9753_26595  twin-arginine translocation signal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
D9753_14275  adenylate kinase [KO:K00939] [EC:2.7.4.3]
D9753_29285  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
D9753_07485  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
D9753_07495  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
D9753_07490  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
D9753_06965  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
D9753_06970  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
D9753_06975  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
D9753_13505  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
D9753_06755  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
D9753_06750  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
D9753_10410  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
D9753_30735  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
D9753_30730  urease subunit beta [KO:K01429] [EC:3.5.1.5]
D9753_30725  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
D9753_10415  ureA; urease subunit gamma [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sdd00030  Pentose phosphate pathway
sdd00220  Arginine biosynthesis
sdd00250  Alanine, aspartate and glutamate metabolism
sdd00260  Glycine, serine and threonine metabolism
sdd00340  Histidine metabolism
sdd00630  Glyoxylate and dicarboxylate metabolism
sdd00730  Thiamine metabolism
sdd00740  Riboflavin metabolism
sdd00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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