KEGG   PATHWAY: taes00130
Entry
taes00130                   Pathway                                
Name
Ubiquinone and other terpenoid-quinone biosynthesis - Triticum aestivum (bread wheat)
Description
Ubiquinone (UQ), also called coenzyme Q, and plastoquinone (PQ) are electron carriers in oxidative phosphorylation and photosynthesis, respectively. The quinoid nucleus of ubiquinone is derived from the shikimate pathway; 4-hydroxybenzoate is directly formed from chorismate in bacteria, while it can be formed from either chorismate or tyrosine in yeast. The following biosynthesis of terpenoid moiety involves reactions of prenylation, decarboxylation, and three hydroxylations alternating with three methylations. The order of these reactions are somewhat different between bacteria and yeast. Phylloquinone (vitamin K1), menaquinone (vitamin K2), and tocopherol (vitamin E) are fat-soluble vitamins. Phylloquinone is a compound present in all photosynthetic plants serving as a cofactor for photosystem I-mediated electron transport. Menaquinone is an obligatory component of the electron-transfer pathway in bacteria.
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
taes00130  Ubiquinone and other terpenoid-quinone biosynthesis
taes00130

Module
taes_M00112  Tocopherol/tocotorienol biosynthesis, homogentisate + phytyl/geranylgeranyl-PP => tocopherol/tocotorienol [PATH:taes00130]
taes_M00932  Phylloquinone biosynthesis, chorismate (+ phytyl-PP) => phylloquinol [PATH:taes00130]
taes_M00933  Plastoquinone biosynthesis, homogentisate + solanesyl-PP => plastoquinol [PATH:taes00130]
Other DBs
GO: 0006744 0009234 0042372
Organism
Triticum aestivum (bread wheat) [GN:taes]
Gene
123058708  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123128624  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123145756  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123165172  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123147760  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123167180  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123097263  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123132659  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123136751  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123085991  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123138505  nicotianamine aminotransferase 1-like isoform X1 [KO:K00815] [EC:2.6.1.5]
123091579  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123091651  probable aminotransferase TAT2 isoform X1 [KO:K00815] [EC:2.6.1.5]
123144236  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123162344  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123109698  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
123077675  trans-cinnamate 4-monooxygenase [KO:K00487] [EC:1.14.14.91]
123060617  trans-cinnamate 4-monooxygenase-like [KO:K00487] [EC:1.14.14.91]
123166406  cytochrome P450 CYP73A100-like [KO:K00487] [EC:1.14.14.91]
123079573  trans-cinnamate 4-monooxygenase [KO:K00487] [EC:1.14.14.91]
123148431  cytochrome P450 CYP73A100-like [KO:K00487] [EC:1.14.14.91]
123062435  trans-cinnamate 4-monooxygenase-like [KO:K00487] [EC:1.14.14.91]
123048956  cytochrome P450 CYP73A100-like [KO:K00487] [EC:1.14.14.91]
123099110  trans-cinnamate 4-monooxygenase-like [KO:K00487] [EC:1.14.14.91]
123191571  cytochrome P450 CYP73A100-like [KO:K00487] [EC:1.14.14.91]
123069147  trans-cinnamate 4-monooxygenase-like [KO:K00487] [EC:1.14.14.91]
123053304  trans-cinnamate 4-monooxygenase-like [KO:K00487] [EC:1.14.14.91]
123159216  cytochrome P450 CYP73A100-like [KO:K00487] [EC:1.14.14.91]
123071222  trans-cinnamate 4-monooxygenase [KO:K00487] [EC:1.14.14.91]
123089637  trans-cinnamate 4-monooxygenase-like [KO:K00487] [EC:1.14.14.91]
123040936  cytochrome P450 CYP73A100-like [KO:K00487] [EC:1.14.14.91]
123108467  trans-cinnamate 4-monooxygenase-like [KO:K00487] [EC:1.14.14.91]
123044016  4-coumarate--CoA ligase 5 isoform X1 [KO:K01904] [EC:6.2.1.12]
123093174  4-coumarate--CoA ligase-like 1 [KO:K01904] [EC:6.2.1.12]
123128073  4-coumarate--CoA ligase 2-like [KO:K01904] [EC:6.2.1.12]
123187773  4-coumarate--CoA ligase 5-like [KO:K01904] [EC:6.2.1.12]
123045214  4-coumarate--CoA ligase-like 9 [KO:K01904] [EC:6.2.1.12]
123188959  4-coumarate--CoA ligase-like 9 [KO:K01904] [EC:6.2.1.12]
123132517  4-coumarate--CoA ligase 3 [KO:K01904] [EC:6.2.1.12]
123149370  4-coumarate--CoA ligase 4-like [KO:K01904] [EC:6.2.1.12]
123169286  4-coumarate--CoA ligase 4-like [KO:K01904] [EC:6.2.1.12]
123098443  4-coumarate--CoA ligase-like 1 [KO:K01904] [EC:6.2.1.12]
123084909  4-coumarate--CoA ligase-like 1 [KO:K01904] [EC:6.2.1.12]
123136589  4-coumarate--CoA ligase 3-like [KO:K01904] [EC:6.2.1.12]
123050793  4-coumarate--CoA ligase-like 3 [KO:K01904] [EC:6.2.1.12]
123051893  4-coumarate--CoA ligase 5-like [KO:K01904] [EC:6.2.1.12]
123137862  4-coumarate--CoA ligase 2-like [KO:K01904] [EC:6.2.1.12]
123053047  4-coumarate--CoA ligase-like 9 [KO:K01904] [EC:6.2.1.12]
123181502  4-coumarate--CoA ligase-like 3 [KO:K01904] [EC:6.2.1.12]
123091620  4-coumarate--CoA ligase-like 3 [KO:K01904] [EC:6.2.1.12]
123144103  4-coumarate--CoA ligase 3-like [KO:K01904] [EC:6.2.1.12]
123145165  4-coumarate--CoA ligase 2 [KO:K01904] [EC:6.2.1.12]
123063356  4-coumarate--CoA ligase-like 7 isoform X1 [KO:K01904] [EC:6.2.1.12]
123072335  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123091112  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123099572  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123117904  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123126311  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123082271  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123080020  4-coumarate--CoA ligase-like 5 [KO:K01904] [EC:6.2.1.12]
123099571  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123086869  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123080021  4-coumarate--CoA ligase-like 5 [KO:K01904] [EC:6.2.1.12]
123094476  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123086870  4-coumarate--CoA ligase-like 5 [KO:K01904] [EC:6.2.1.12]
123091109  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123096111  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
123071672  4-coumarate--CoA ligase-like 5 [KO:K01904] [EC:6.2.1.12]
123062828  4-coumarate--CoA ligase-like 5 [KO:K01904] [EC:6.2.1.12]
123062827  4-coumarate--CoA ligase-like 5 [KO:K01904] [EC:6.2.1.12]
123129153  4-hydroxybenzoate polyprenyltransferase, mitochondrial-like isoform X1 [KO:K06125] [EC:2.5.1.39]
123117613  4-hydroxybenzoate polyprenyltransferase, mitochondrial-like [KO:K06125] [EC:2.5.1.39]
123135239  4-hydroxybenzoate polyprenyltransferase, mitochondrial-like [KO:K06125] [EC:2.5.1.39]
123142252  4-hydroxybenzoate polyprenyltransferase, mitochondrial-like [KO:K06125] [EC:2.5.1.39]
123114196  ubiquinone biosynthesis monooxygenase COQ6, mitochondrial-like isoform X1 [KO:K06126] [EC:1.14.13.-]
123084128  ubiquinone biosynthesis monooxygenase COQ6, mitochondrial-like [KO:K06126] [EC:1.14.13.-]
123087733  ubiquinone biosynthesis monooxygenase COQ6, mitochondrial-like [KO:K06126] [EC:1.14.13.-]
123123683  ubiquinone biosynthesis monooxygenase COQ6, mitochondrial-like isoform X1 [KO:K06126] [EC:1.14.13.-]
123165173  ubiquinone biosynthesis O-methyltransferase, mitochondrial-like [KO:K00591] [EC:2.1.1.114 2.1.1.64]
123151503  ubiquinone biosynthesis O-methyltransferase, mitochondrial-like [KO:K00591] [EC:2.1.1.114 2.1.1.64]
123160250  ubiquinone biosynthesis O-methyltransferase, mitochondrial-like [KO:K00591] [EC:2.1.1.114 2.1.1.64]
123047002  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial-like [KO:K06127] [EC:2.1.1.201]
123190680  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial-like [KO:K06127] [EC:2.1.1.201]
123054837  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial [KO:K06127] [EC:2.1.1.201]
123111778  isochorismate synthase 2, chloroplastic-like [KO:K02552] [EC:5.4.4.2]
123121341  isochorismate synthase 2, chloroplastic-like [KO:K02552] [EC:5.4.4.2]
123103578  isochorismate synthase 2, chloroplastic-like [KO:K02552] [EC:5.4.4.2]
123137052  protein PHYLLO, chloroplastic-like isoform X1 [KO:K14759] [EC:5.4.4.2 2.2.1.9 4.2.99.20 4.2.1.113]
123144651  protein PHYLLO, chloroplastic-like isoform X1 [KO:K14759] [EC:5.4.4.2 2.2.1.9 4.2.99.20 4.2.1.113]
123127572  protein PHYLLO, chloroplastic-like isoform X1 [KO:K14759] [EC:5.4.4.2 2.2.1.9 4.2.99.20 4.2.1.113]
123167290  2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomal-like [KO:K14760] [EC:6.2.1.26]
123150942  2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomal-like [KO:K14760] [EC:6.2.1.26]
123162101  2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomal-like isoform X1 [KO:K14760] [EC:6.2.1.26]
123078727  1,4-dihydroxy-2-naphthoyl-CoA synthase, peroxisomal-like [KO:K01661] [EC:4.1.3.36]
123061656  1,4-dihydroxy-2-naphthoyl-CoA synthase, peroxisomal-like [KO:K01661] [EC:4.1.3.36]
123070278  1,4-dihydroxy-2-naphthoyl-CoA synthase, peroxisomal-like [KO:K01661] [EC:4.1.3.36]
123077142  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123060136  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123094283  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123094284  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123165528  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123096523  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123099407  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123099408  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123068611  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123180170  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123087233  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like isoform X1 [KO:K19222] [EC:3.1.2.28]
123087235  uncharacterized protein LOC123087235 isoform X1 [KO:K19222] [EC:3.1.2.28]
123087805  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123158988  uncharacterized protein LOC123158988 [KO:K19222] [EC:3.1.2.28]
123105615  uncharacterized protein LOC123105615 isoform X1 [KO:K19222] [EC:3.1.2.28]
123106266  1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1-like [KO:K19222] [EC:3.1.2.28]
123124847  LOW QUALITY PROTEIN: uncharacterized protein LOC123124847 [KO:K19222] [EC:3.1.2.28]
123043710  uncharacterized protein LOC123043710 isoform X1 [KO:K23094] [EC:2.5.1.130]
123093450  2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic-like [KO:K23094] [EC:2.5.1.130]
123168616  2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic-like [KO:K23094] [EC:2.5.1.130]
123098729  2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic-like [KO:K23094] [EC:2.5.1.130]
123088098  2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic-like isoform X1 [KO:K23094] [EC:2.5.1.130]
123066137  2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic-like isoform X1 [KO:K23094] [EC:2.5.1.130]
123148304  alternative NAD(P)H-ubiquinone oxidoreductase C1, chloroplastic/mitochondrial-like isoform X1 [KO:K17872] [EC:1.6.5.12]
123161869  alternative NAD(P)H-ubiquinone oxidoreductase C1, chloroplastic/mitochondrial-like isoform X1 [KO:K17872] [EC:1.6.5.12]
123164500  alternative NAD(P)H-ubiquinone oxidoreductase C1, chloroplastic/mitochondrial-like isoform X1 [KO:K17872] [EC:1.6.5.12]
123045984  2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplastic-like isoform X1 [KO:K23095] [EC:2.1.1.329]
123189733  2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplastic-like isoform X1 [KO:K23095] [EC:2.1.1.329]
123189751  2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplastic-like [KO:K23095] [EC:2.1.1.329]
123053859  2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplastic-like isoform X1 [KO:K23095] [EC:2.1.1.329]
123043477  probable NAD(P)H dehydrogenase (quinone) FQR1-like 1 [KO:K03809] [EC:1.6.5.2]
123043824  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123094951  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123061454  NAD(P)H dehydrogenase (quinone) FQR1-like [KO:K03809] [EC:1.6.5.2]
123079401  NAD(P)H dehydrogenase (quinone) FQR1-like [KO:K03809] [EC:1.6.5.2]
123113309  probable NAD(P)H dehydrogenase (quinone) FQR1-like 1 [KO:K03809] [EC:1.6.5.2]
123062269  NAD(P)H dehydrogenase (quinone) FQR1-like [KO:K03809] [EC:1.6.5.2]
123168358  NAD(P)H dehydrogenase (quinone) FQR1-like [KO:K03809] [EC:1.6.5.2]
123081838  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123169998  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123048813  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123049278  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123049279  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123100024  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123119003  probable NAD(P)H dehydrogenase (quinone) FQR1-like 1 [KO:K03809] [EC:1.6.5.2]
123152487  NAD(P)H dehydrogenase (quinone) FQR1-like [KO:K03809] [EC:1.6.5.2]
123153312  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123051690  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123138602  NAD(P)H dehydrogenase (quinone) FQR1-like [KO:K03809] [EC:1.6.5.2]
123180873  probable NAD(P)H dehydrogenase (quinone) FQR1-like 1 [KO:K03809] [EC:1.6.5.2]
123122824  probable NAD(P)H dehydrogenase (quinone) FQR1-like 1 [KO:K03809] [EC:1.6.5.2]
123071027  NAD(P)H dehydrogenase (quinone) FQR1-like [KO:K03809] [EC:1.6.5.2]
123105020  probable NAD(P)H dehydrogenase (quinone) FQR1-like 1 [KO:K03809] [EC:1.6.5.2]
123161194  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123161883  NAD(P)H dehydrogenase (quinone) FQR1-like [KO:K03809] [EC:1.6.5.2]
123182518  NAD(P)H dehydrogenase (quinone) FQR1-like [KO:K03809] [EC:1.6.5.2]
123041286  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123184820  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123184821  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123185340  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123185341  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123185342  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123185343  quinone-oxidoreductase QR2-like [KO:K03809] [EC:1.6.5.2]
123075985  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
123166129  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
123132423  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
123136502  4-hydroxyphenylpyruvate dioxygenase-like isoform X1 [KO:K00457] [EC:1.13.11.27]
780622  4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
123065273  probable homogentisate phytyltransferase 2, chloroplastic [KO:K12501] [EC:2.5.1.117]
123142883  probable homogentisate phytyltransferase 2, chloroplastic [KO:K12501] [EC:2.5.1.117]
123182829  probable homogentisate phytyltransferase 2, chloroplastic [KO:K12501] [EC:2.5.1.117]
123095599  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 2, chloroplastic-like [KO:K12502] [EC:2.1.1.295]
123119319  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 2, chloroplastic-like [KO:K12502] [EC:2.1.1.295]
123102141  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 2, chloroplastic-like [KO:K12502] [EC:2.1.1.295]
123137605  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 1, chloroplastic-like [KO:K12502] [EC:2.1.1.295]
123087377  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 2, chloroplastic-like [KO:K12502] [EC:2.1.1.295]
123090555  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 2, chloroplastic-like [KO:K12502] [EC:2.1.1.295]
100415847  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 2, chloroplastic [KO:K12502] [EC:2.1.1.295]
123127840  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 1, chloroplastic-like [KO:K12502] [EC:2.1.1.295]
123144936  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 1, chloroplastic [KO:K12502] [EC:2.1.1.295]
123165791  probable homogentisate phytyltransferase 1, chloroplastic [KO:K09833] [EC:2.5.1.115 2.5.1.116]
123166512  homogentisate geranylgeranyltransferase-like isoform X1 [KO:K09833] [EC:2.5.1.115 2.5.1.116]
123149361  probable homogentisate phytyltransferase 1, chloroplastic [KO:K09833] [EC:2.5.1.115 2.5.1.116]
543094  homogentisate geranylgeranyltransferase isoform X1 [KO:K09833] [EC:2.5.1.115 2.5.1.116]
780685  probable homogentisate phytyltransferase 1, chloroplastic [KO:K09833] [EC:2.5.1.115 2.5.1.116]
123128989  probable tocopherol cyclase, chloroplastic [KO:K09834] [EC:5.5.1.24]
123052679  probable tocopherol cyclase, chloroplastic [KO:K09834] [EC:5.5.1.24]
123181719  probable tocopherol cyclase, chloroplastic isoform X1 [KO:K09834] [EC:5.5.1.24]
123128104  probable tocopherol O-methyltransferase, chloroplastic [KO:K05928] [EC:2.1.1.95]
123137891  probable tocopherol O-methyltransferase, chloroplastic [KO:K05928] [EC:2.1.1.95]
780621  probable tocopherol O-methyltransferase, chloroplastic [KO:K05928] [EC:2.1.1.95]
Compound
C00082  L-Tyrosine
C00156  4-Hydroxybenzoate
C00223  p-Coumaroyl-CoA
C00251  Chorismate
C00341  Geranyl diphosphate
C00353  Geranylgeranyl diphosphate
C00390  Ubiquinol
C00423  trans-Cinnamate
C00544  Homogentisate
C00811  4-Coumarate
C00828  Menaquinone
C00885  Isochorismate
C01179  3-(4-Hydroxyphenyl)pyruvate
C02059  Phylloquinone
C02477  alpha-Tocopherol
C02483  gamma-Tocopherol
C02730  2-Succinylbenzoate
C02949  4-Hydroxybenzoyl-CoA
C03160  2-Succinylbenzoyl-CoA
C03313  Phylloquinol
C03657  1,4-Dihydroxy-2-naphthoate
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C03993  4-(beta-D-Glucosyloxy)benzoate
C04145  all-trans-Nonaprenyl diphosphate
C05427  Phytyl diphosphate
C05807  2-Polyprenylphenol
C05817  (1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate
C05819  Menaquinol
C05847  all-trans-Polyprenyl diphosphate
C05848  4-Hydroxy-3-polyprenylbenzoate
C05849  Vitamin K1 epoxide
C06986  Spirodilactone
C10793  Geranylhydroquinone
C13309  2-Phytyl-1,4-naphthoquinone
C14151  delta-Tocopherol
C14152  beta-Tocopherol
C14153  alpha-Tocotrienol
C14154  beta-Tocotrienol
C14155  gamma-Tocotrienol
C14156  delta-Tocotrienol
C15547  1,4-Dihydroxy-2-naphthoyl-CoA
C15882  2-Methyl-6-phytylquinol
C15883  2,3-Dimethyl-5-phytylquinol
C16519  2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate
C16695  Plastoquinol-9
C16999  Futalosine
C17010  Dehypoxanthine futalosine
C17017  Cyclic dehypoxanthine futalosine
C17018  1,4-Dihydroxy-6-naphthoate
C17412  Shikonin
C17551  2-Polyprenyl-6-hydroxyphenol
C17552  2-Polyprenyl-6-methoxyphenol
C17554  3,4-Dihydroxy-5-polyprenylbenzoate
C17559  3-Methoxy-4-hydroxy-5-polyprenylbenzoate
C17570  2-Methyl-6-solanyl-1,4-benzoquinol
C18131  Geranyl-hydroxybenzoate
C18132  3''-Hydroxy-geranylhydroquinone
C18133  Deoxyshikonin
C18134  Dihydroechinofuran
C18135  Dihydroshikonofuran
C19847  Demethylmenaquinol
C19858  2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol
C19859  6-Methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol
C20265  2,3-Epoxymenaquinone
C20737  6-Geranylgeranyl-2-methylbenzene-1,4-diol
C20738  6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol
C20772  3-[(1-Carboxyvinyl)oxy]benzoate
C20773  6-Amino-6-deoxyfutalosine
C21084  Demethylphylloquinol
C21860  3-Demethylubiquinol
C22039  2-Carboxy-1,4-naphthoquinone
Reference
PMID:12908086
  Authors
Ward MJ, Fu QS, Rhoads KR, Yeung CH, Spormann AM, Criddle CS.
  Title
A derivative of the menaquinone precursor 1,4-dihydroxy-2-naphthoate is involved in the reductive transformation of carbon tetrachloride by aerobically grown Shewanella oneidensis MR-1.
  Journal
Appl Microbiol Biotechnol 63:571-7 (2004)
DOI:10.1007/s00253-003-1407-3
Reference
PMID:14499605
  Authors
Monzingo AF, Gao J, Qiu J, Georgiou G, Robertus JD.
  Title
The X-ray structure of Escherichia coli RraA (MenG), A protein inhibitor of RNA processing.
  Journal
J Mol Biol 332:1015-24 (2003)
DOI:10.1016/S0022-2836(03)00970-7
Reference
PMID:11470786
  Authors
Johnson TW, Zybailov B, Jones AD, Bittl R, Zech S, Stehlik D, Golbeck JH, Chitnis PR.
  Title
Recruitment of a foreign quinone into the A1 site of photosystem I. In vivo replacement of plastoquinone-9 by media-supplemented naphthoquinones in phylloquinone biosynthetic pathway mutants of Synechocystis sp. PCC 6803.
  Journal
J Biol Chem 276:39512-21 (2001)
DOI:10.1074/jbc.M104040200
Reference
PMID:12615349
  Authors
Wade Johnson T, Naithani S, Stewart C Jr, Zybailov B, Daniel Jones A, Golbeck JH, Chitnis PR.
  Title
The menD and menE homologs code for 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylate synthase and O-succinylbenzoic acid-CoA synthase in the phylloquinone biosynthetic pathway of Synechocystis sp. PCC 6803.
  Journal
Biochim Biophys Acta 1557:67-76 (2003)
DOI:10.1016/S0005-2728(02)00396-1
Reference
PMID:12721307
  Authors
Gin P, Hsu AY, Rothman SC, Jonassen T, Lee PT, Tzagoloff A, Clarke CF.
  Title
The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis.
  Journal
J Biol Chem 278:25308-16 (2003)
DOI:10.1074/jbc.M303234200
Reference
PMID:18284213
  Authors
Jiang M, Chen X, Guo ZF, Cao Y, Chen M, Guo Z.
  Title
Identification and Characterization of (1R,6R)-2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate Synthase in the Menaquinone Biosynthesis of Escherichia coli.
  Journal
Biochemistry 47:3426-34 (2008)
DOI:10.1021/bi7023755
Reference
PMID:17760421
  Authors
Jiang M, Cao Y, Guo ZF, Chen M, Chen X, Guo Z.
  Title
Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity.
  Journal
Biochemistry 46:10979-89 (2007)
DOI:10.1021/bi700810x
Reference
PMID:17956107
  Authors
Jiang M, Chen M, Cao Y, Yang Y, Sze KH, Chen X, Guo Z.
  Title
Determination of the stereochemistry of 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate, a key intermediate in menaquinone biosynthesis.
  Journal
Org Lett 9:4765-7 (2007)
DOI:10.1021/ol702126m
Reference
PMID:18801996
  Authors
Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T
  Title
An alternative menaquinone biosynthetic pathway operating in microorganisms.
  Journal
Science 321:1670-3 (2008)
DOI:10.1126/science.1160446
Reference
PMID:12232327
  Authors
Loscher R, Heide L
  Title
Biosynthesis of p-Hydroxybenzoate from p-Coumarate and p-Coumaroyl-Coenzyme A in Cell-Free Extracts of Lithospermum erythrorhizon Cell Cultures.
  Journal
Plant Physiol 106:271-279 (1994)
DOI:10.1104/pp.106.1.271
Reference
PMID:11583838
  Authors
Meganathan R
  Title
Ubiquinone biosynthesis in microorganisms.
  Journal
FEMS Microbiol Lett 203:131-9 (2001)
DOI:10.1111/j.1574-6968.2001.tb10831.x
Reference
PMID:14508009
  Authors
Cheng Z, Sattler S, Maeda H, Sakuragi Y, Bryant DA, DellaPenna D
  Title
Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes.
  Journal
Plant Cell 15:2343-56 (2003)
DOI:10.1105/tpc.013656
Reference
PMID:16989822
  Authors
Sadre R, Gruber J, Frentzen M
  Title
Characterization of homogentisate prenyltransferases involved in plastoquinone-9 and tocochromanol biosynthesis.
  Journal
FEBS Lett 580:5357-62 (2006)
DOI:10.1016/j.febslet.2006.09.002
Reference
PMID:12523993
  Authors
Hofius D, Sonnewald U.
  Title
Vitamin E biosynthesis: biochemistry meets cell biology.
  Journal
Trends Plant Sci 8:6-8 (2003)
DOI:10.1016/S1360-1385(02)00002-X
Reference
PMID:16233343
  Authors
Kawamukai M
  Title
Biosynthesis, bioproduction and novel roles of ubiquinone.
  Journal
J Biosci Bioeng 94:511-7 (2002)
DOI:10.1016/S1389-1723(02)80188-8
Reference
PMID:21239697
  Authors
Tie JK, Jin DY, Straight DL, Stafford DW
  Title
Functional study of the vitamin K cycle in mammalian cells.
  Journal
Blood 117:2967-74 (2011)
DOI:10.1182/blood-2010-08-304303
Reference
PMID:23113660
  Authors
Zhou L, Wang JY, Wu J, Wang J, Poplawsky A, Lin S, Zhu B, Chang C, Zhou T, Zhang LH, He YW
  Title
The diffusible factor synthase XanB2 is a bifunctional chorismatase that links the shikimate pathway to ubiquinone and xanthomonadins biosynthetic pathways.
  Journal
Mol Microbiol 87:80-93 (2013)
DOI:10.1111/mmi.12084
Related
pathway
taes00190  Oxidative phosphorylation
taes00400  Phenylalanine, tyrosine and tryptophan biosynthesis
taes00900  Terpenoid backbone biosynthesis
taes00940  Phenylpropanoid biosynthesis
KO pathway
ko00130   
LinkDB

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