KEGG   PATHWAY: tec00630
Entry
tec00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Thioclava electrotropha
Class
Metabolism; Carbohydrate metabolism
Pathway map
tec00630  Glyoxylate and dicarboxylate metabolism
tec00630

Module
tec_M00373  Ethylmalonyl pathway [PATH:tec00630]
tec_M00621  Glycine cleavage system [PATH:tec00630]
tec_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:tec00630]
Other DBs
GO: 0046487 0043648
Organism
Thioclava electrotropha [GN:tec]
Gene
AKL02_004555  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
AKL02_011465  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
AKL02_016510  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
AKL02_012610  malate synthase G [KO:K01638] [EC:2.3.3.9]
AKL02_002845  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
AKL02_005510  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
AKL02_013710  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
AKL02_011830  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
AKL02_000915  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
AKL02_001015  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
AKL02_008360  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AKL02_016740  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
AKL02_016995  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
AKL02_018870  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
AKL02_017000  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
AKL02_007510  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
AKL02_018635  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
AKL02_016040  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
AKL02_018630  protein meaA [KO:K14447] [EC:5.4.99.63]
AKL02_018800  acyl-CoA/acyl-ACP dehydrogenase [KO:K14448] [EC:1.3.8.12]
AKL02_005540  MaoC family dehydratase [KO:K14449] [EC:4.2.1.148]
AKL02_016915  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
AKL02_005525  CoA ester lyase [KO:K14451] [EC:3.1.2.30]
AKL02_012760  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
AKL02_012785  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
AKL02_012745  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
AKL02_014080  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
AKL02_014075  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
AKL02_014070  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
AKL02_004785  catalase [KO:K03781] [EC:1.11.1.6]
AKL02_016100  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
AKL02_015385  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
AKL02_002815  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
AKL02_007125  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
AKL02_010415  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
AKL02_016565  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
AKL02_010375  form I ribulose bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
AKL02_010380  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
AKL02_015700  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
AKL02_017520  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
AKL02_000205  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AKL02_004235  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AKL02_005755  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AKL02_011720  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
AKL02_016200  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AKL02_017155  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AKL02_005840  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
AKL02_005830  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
AKL02_005470  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
AKL02_006470  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
AKL02_007890  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
AKL02_005835  gcvH; glycine cleavage system protein GcvH [KO:K02437]
AKL02_019495  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
AKL02_003640  NAD(P)-dependent oxidoreductase [KO:K00042] [EC:1.1.1.60]
AKL02_013795  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
AKL02_004360  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
AKL02_013465  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
AKL02_017260  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
AKL02_017270  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
AKL02_017275  formate dehydrogenase [KO:K00124]
AKL02_017280  formate dehydrogenase subunit gamma [KO:K00127]
AKL02_008550  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
AKL02_005985  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
AKL02_003365  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
tec00010  Glycolysis / Gluconeogenesis
tec00020  Citrate cycle (TCA cycle)
tec00030  Pentose phosphate pathway
tec00053  Ascorbate and aldarate metabolism
tec00071  Fatty acid degradation
tec00230  Purine metabolism
tec00250  Alanine, aspartate and glutamate metabolism
tec00260  Glycine, serine and threonine metabolism
tec00620  Pyruvate metabolism
tec00710  Carbon fixation by Calvin cycle
tec00750  Vitamin B6 metabolism
tec00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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